D-dimer is a protein fragment which has two cross linked D fragment of protein called fibrin. It is a fibrin degradation product (FDP) which is found in human blood sample after the blood clot is degraded by fibrinolysis. They are present in blood plasma only when blood coagulation system has been activated due to presence of disseminated intravascular coagulation or thrombosis. D-dimers are responsible for activation of the haemostatic system. Driving factors for the growth of this market are increasing occurrence of various pulmonary and cardiovascular diseases which can cause various life threatening issues due to blood clot formation in the pulmonary and arterial pathway. Increasing incidence of pulmonary embolisms and heart strokes and rising demand for advanced coagulation testing techniques which brings more revenues to this market. It examines overall market applications of monoclonal antibodies, chromogenic substrates, DNA probes, immunoassays, biochips/microarrays, IT and other technologies.
On the basis of disease diagnoses, the D-dimer market can be classified into three major segments namely deep venous thrombosis (DVT), pulmonary embolism (PE)and venous thromboembolism (VTE). Standardized D-Dimer is expected to offer opportunities for quality control products, services and is highly useful in the setting of emergency department. There are different D-dimer assays qualitative and quantitative and both tests are highly sensitive and show predictive values. The level of D-dimer is higher in non-pathological conditions such as pregnancy, age specially in geriatric , cigarette smoking, race, post-operatively, functional impairment, genetic factors and in pathological conditions such as acute coronary syndromes, aortic dissection, acute upper gastrointestinal hemorrhage, atrial fibrillation, arterial or venous thromboembolism, infection, consumptive coagulopathy such as VICC and DIC, pre-eclampsia, malignancy, stroke, sickle cell disease, trauma and superficial thrombophlebitis.
The D-dimer market is segmented into four major regions such as Europe, North America, Asia- Pacific and RoW. North American market dominates the global market followed by European market due increasing technology and rising clinical trial studies and medical practices. Asia-Pacific region shows the fastest growth rate due to rising incidence rates of cardiovascular diseases due to changing lifestyle and habits, increasing competition. Some of the key players operating in this market include Abbott Laboratories, Inc., Becton, Bio/Data Corporation, Beckman Coulter Inc., Dickinson & Company, Corgenix, F. Nanogen, Hoffmann-La Roche Ltd., Siemens Healthcare, Trinity Biotech plc., Thermo & Fischer Scientific, Inc.
This report by Grand View Research provides complete market estimates and forecasts up to 2020. The study also explains in detail various market dynamics including key drivers, restraints, growth opportunities and competitive landscape. Key questions answered by the report include:
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