Global Hereditary Angioedema Therapeutics Market Size & Outlook

The global hereditary angioedema therapeutics market size was estimated at USD 3,600.4 million in 2025 and is projected to reach USD 8,182.0 million by 2033, growing at a CAGR of 10.4% from 2026 to 2033.
Revenue, 2025 (US$M)
$3,600.4
Forecast, 2033 (US$M)
$8,182.0
CAGR, 2026 - 2033
10.4%
Report Coverage
Worldwide

Global hereditary angioedema therapeutics market, 2021-2033 (US$M)

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Global hereditary angioedema therapeutics market highlights

  • The global hereditary angioedema therapeutics market generated a revenue of USD 3,600.4 million in 2025 and is expected to reach USD 8,182.0 million by 2033.
  • The market is expected to grow at a CAGR (2026 - 2033) of 10.4% by 2033.
  • In terms of segment, kallikrein inhibitor accounted for a revenue of USD 1,912.6 million in 2025.
  • Kallikrein inhibitor is the most lucrative treatment segment registering the fastest growth during the forecast period.
  • In terms of region, North America was the largest revenue generating market in 2025.
  • Country-wise, India is expected to register the highest CAGR from 2026 to 2033.

Global data book summary

Market revenue in 2025USD 3,600.4 million
Market revenue in 2033USD 8,182.0 million
Growth rate10.4% (CAGR from 2026 to 2033)
Largest segmentKallikrein inhibitor
Fastest growing segmentKallikrein inhibitor
Historical data covered2021 - 2024
Base year for estimation2025
Forecast period covered2026 - 2033
Quantitative unitsRevenue in USD million
Market segmentationC1-Inhibitor Concentrates, Bradykinin B2 receptor antagonist, Kallikrein inhibitor

Other key industry trends

  • In terms of revenue, the North America accounted for 39.5% of the global hereditary angioedema therapeutics market in 2025.
  • By country, the U.S. is projected to lead the global market in terms of revenue in 2033.
  • By country, India is the fastest growing regional market and is projected to reach USD 304.6 million by 2033.

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Hereditary Angioedema Therapeutics Market Companies

Name Profile # Employees HQ Website
Attune Pharmaceuticals View profile 1-10 New York, New York, United States, North America http://attunepharma.com/
Pharming Group View profile 382 Darwinweg 24, Leiden, ZH, Netherlands, 2333 CR https://www.pharming.com
KalVista Pharmaceuticals Inc View profile 118 55 Cambridge Parkway, Suite 901 East, Cambridge, MA, United States, 02142 https://www.kalvista.com
Adverum Biotechnologies Inc View profile 121 100 Cardinal Way, Redwood CIty, CA, United States, 94063 https://www.adverum.com
BioCryst Pharmaceuticals Inc View profile 531 4505 Emperor Boulevard, Suite 200, Durham, NC, United States, 27703 https://www.biocryst.com
Ionis Pharmaceuticals Inc View profile 927 2855 Gazelle Court, Carlsbad, CA, United States, 92010 https://www.ionispharma.com
Takeda Pharmaceutical Co Ltd View profile 49095 1-1, Nihonbashi-Honcho 2-Chome, Chuo-ku, Tokyo, Japan, 103-8668 https://www.takeda.com
CSL Ltd View profile 32000 655 Elizabeth Street, Melbourne, VIC, Australia, 3000 https://www.csl.com

Global hereditary angioedema therapeutics market outlook

The databook is designed to serve as a comprehensive guide to navigating this sector. The databook focuses on market statistics denoted in the form of revenue and y-o-y growth and CAGR across the globe and regions. A detailed competitive and opportunity analyses related to hereditary angioedema therapeutics market will help companies and investors design strategic landscapes.


Kallikrein inhibitor was the largest segment with a revenue share of 53.12% in 2025. Horizon Databook has segmented the Global hereditary angioedema therapeutics market based on c1-inhibitor concentrates, bradykinin b2 receptor antagonist, kallikrein inhibitor covering the revenue growth of each sub-segment from 2021 to 2033.


  • Global Hereditary Angioedema Therapeutics Treatment Outlook (Revenue, USD Million, 2021-2033)
    • Bradykinin B2 receptor antagonist
    • Others
    • C1-Inhibitor Concentrates
    • Kallikrein inhibitor
  • Global Hereditary Angioedema Therapeutics End Use Outlook (Revenue, USD Million, 2021-2033)
    • Prophylaxis
    • On-demand
  • Global Hereditary Angioedema Therapeutics Route of Administration Outlook (Revenue, USD Million, 2021-2033)
    • Intravenous
    • Oral
    • Subcutaneous

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Horizon Databook provides a detailed overview of global-level data and insights on the Global hereditary angioedema therapeutics market, including forecasts for subscribers. This global databook contains high-level insights into Global hereditary angioedema therapeutics market from 2021 to 2033, including revenue numbers, major trends, and company profiles.

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Global hereditary angioedema therapeutics market, by region, 2025 (US$M)

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