South Africa Hereditary Angioedema Therapeutics Market Size & Outlook
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South Africa hereditary angioedema therapeutics market highlights
- The South Africa hereditary angioedema therapeutics market generated a revenue of USD 28.9 million in 2025 and is expected to reach USD 74.3 million by 2033.
- The South Africa market is expected to grow at a CAGR of 12.1% from 2026 to 2033.
- In terms of segment, kallikrein inhibitor was the largest revenue generating treatment in 2025.
- Kallikrein inhibitor is the most lucrative treatment segment registering the fastest growth during the forecast period.
Hereditary angioedema therapeutics market data book summary
| Market revenue in 2025 | USD 28.9 million |
| Market revenue in 2033 | USD 74.3 million |
| Growth rate | 12.1% (CAGR from 2026 to 2033) |
| Largest segment | Kallikrein inhibitor |
| Fastest growing segment | Kallikrein inhibitor |
| Historical data | 2021 - 2024 |
| Base year | 2025 |
| Forecast period | 2026 - 2033 |
| Quantitative units | Revenue in USD million |
| Market segmentation | C1-Inhibitor Concentrates, Bradykinin B2 receptor antagonist, Kallikrein inhibitor |
| Key market players worldwide | BioCryst Pharmaceuticals Inc, Ionis Pharmaceuticals Inc, CSL Ltd, Adverum Biotechnologies Inc, KalVista Pharmaceuticals Inc, Takeda Pharmaceutical Co Ltd, Pharming Group, Attune Pharmaceuticals |
Other key industry trends
- In terms of revenue, South Africa accounted for 0.8% of the global hereditary angioedema therapeutics market in 2025.
- Country-wise, U.S. is expected to lead the global market in terms of revenue in 2033.
- In Middle East & Africa, Saudi Arabia hereditary angioedema therapeutics market is projected to lead the regional market in terms of revenue in 2033.
- South Africa is the fastest growing regional market in Middle East & Africa and is projected to reach USD 74.3 million by 2033.
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Hereditary Angioedema Therapeutics Market Scope
Hereditary Angioedema Therapeutics Market Companies
| Name | Profile | # Employees | HQ | Website |
|---|---|---|---|---|
| Attune Pharmaceuticals | View profile | 1-10 | New York, New York, United States, North America | http://attunepharma.com/ |
| Pharming Group | View profile | 382 | Darwinweg 24, Leiden, ZH, Netherlands, 2333 CR | https://www.pharming.com |
| KalVista Pharmaceuticals Inc | View profile | 118 | 55 Cambridge Parkway, Suite 901 East, Cambridge, MA, United States, 02142 | https://www.kalvista.com |
| Adverum Biotechnologies Inc | View profile | 121 | 100 Cardinal Way, Redwood CIty, CA, United States, 94063 | https://www.adverum.com |
| BioCryst Pharmaceuticals Inc | View profile | 531 | 4505 Emperor Boulevard, Suite 200, Durham, NC, United States, 27703 | https://www.biocryst.com |
| Ionis Pharmaceuticals Inc | View profile | 927 | 2855 Gazelle Court, Carlsbad, CA, United States, 92010 | https://www.ionispharma.com |
| Takeda Pharmaceutical Co Ltd | View profile | 49095 | 1-1, Nihonbashi-Honcho 2-Chome, Chuo-ku, Tokyo, Japan, 103-8668 | https://www.takeda.com |
| CSL Ltd | View profile | 32000 | 655 Elizabeth Street, Melbourne, VIC, Australia, 3000 | https://www.csl.com |
South Africa hereditary angioedema therapeutics market outlook
The databook is designed to serve as a comprehensive guide to navigating this sector. The databook focuses on market statistics denoted in the form of revenue and y-o-y growth and CAGR across the globe and regions. A detailed competitive and opportunity analyses related to hereditary angioedema therapeutics market will help companies and investors design strategic landscapes.
Kallikrein inhibitor was the largest segment with a revenue share of 54.33% in 2025. Horizon Databook has segmented the South Africa hereditary angioedema therapeutics market based on c1-inhibitor concentrates, bradykinin b2 receptor antagonist, kallikrein inhibitor covering the revenue growth of each sub-segment from 2021 to 2033.
South Africa's hereditary angioedema therapeutics market is expected to witness lucrative growth over the forecast period, owing to the increasing prevalence of HAE, supportive government initiatives, and increased demand for effective therapeutics.
According to a review article published by the Division of Allergology and Clinical Immunology, the estimated prevalence of HAE in the country is 1 per 150,000 cases, close to 400 cases of HAE. Several initiatives enabling better and affordable access to treatment are being taken in the country.
For instance, in February 2023, Sinovuyo South African Virtual Angioedema Centre, a newly established medical help platform, was launched at UCT to provide affordable access to HAE treatment nationwide.
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Horizon Databook provides a detailed overview of country-level data and insights on the South Africa hereditary angioedema therapeutics market, including forecasts for subscribers. This country databook contains high-level insights into South Africa hereditary angioedema therapeutics market from 2021 to 2033, including revenue numbers, major trends, and company profiles.
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South Africa hereditary angioedema hae therapeutics market size, by treatment, 2021-2033 (US$M)
South Africa Hereditary Angioedema Therapeutics Market Share, 2025 & 2033 (US$M)
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