CRISPR And Cas Genes Market Size, Share & Trends Report

CRISPR And Cas Genes Market Size, Share & Trends Analysis Report By Product & Service, By Application (Biomedical, Agricultural), By End-use (Biotechnology & Pharmaceutical Companies), By Region, And Segment Forecasts, 2023 - 2030

Report ID: GVR-1-68038-375-1
Number of Pages: 140
Format: Electronic (PDF)

Historical Range: 2018 - 2021
Industry: Healthcare

Market Segmentation

CRISPR & Cas Genes Product & Service Outlook (Revenue, USD Million, 2018 - 2030)
- By Product
  - Kits & Enzymes
    - Vector-based Cas
    - DNA-free Cas
  - Libraries
  - Design Tool
  - Antibodies
  - Others
- By Service
  - Cell Line Engineering
  - gRNA Design
  - Microbial Gene Editing
  - DNA synthesis
CRISPR & Cas Genes Application Outlook (Revenue, USD Million, 2018 - 2030)
- Biomedical
  - Genome Engineering
  - Disease Model Studies
  - Functional Genomics
  - Epigenetics
  - Others
- Agricultural
CRISPR & Cas Genes End-use Outlook (Revenue, USD Million, 2018 - 2030)
- Biotechnology & Pharmaceutical Companies
- Academics & Government Research Institutes
- Contract Research Organizations (CROs)
CRISPR & Cas Genes Regional Outlook (Revenue, USD Million, 2018 - 2030)
- North America
  - North America CRISPR and Cas Genes Market, By Product & Service
    - By Product
      - Kits & Enzymes
        
        Vector-based Cas9
        
        DNA-free Cas9
      - Libraries
      - Design Tool
      - Antibodies
      - Others
    - By Service
      - Cell Line Engineering
      - gRNA Design
      - Microbial Gene Editing
      - DNA synthesis
  - North America CRISPR and Cas Genes Market, By Application
    - Biomedical
      - Genome Engineering
      - Disease Model Studies
      - Functional Genomics
      - Epigenetics
      - Others
    - Agricultural
  - North America CRISPR and Cas Genes Market, By End-use
    - Biotechnology & Pharmaceutical Companies
    - Academics & Government Research Institutes
    - Contract Research Organizations (CROs)
  - U.S.
  - Canada
    - Canada CRISPR and Cas Genes Market, By Product & Service
      - By Product
        
        Kits & Enzymes
        
        Vector-based Cas9
        
        DNA-free Cas9
        
        Libraries
        
        Design Tool
        
        Antibodies
        
        Others
      - By Service
        
        Cell Line Engineering
        
        gRNA Design
        
        Microbial Gene Editing
        
        DNA synthesis
    - Canada CRISPR and Cas Genes Market, By Application
      - Biomedical
        
        Genome Engineering
        
        Disease Model Studies
        
        Functional Genomics
        
        Epigenetics
        
        Others
      - Agricultural
    - Canada CRISPR and Cas Genes Market, By End-use
      - Biotechnology & Pharmaceutical Companies
      - Academics & Government Research Institutes
      - Contract Research Organizations (CROs)
- Europe
  - Europe CRISPR and Cas Genes Market, By Product & Service
    - By Product
      - Kits & Enzymes
        
        Vector-based Cas9
        
        DNA-free Cas9
      - Libraries
      - Design Tool
      - Antibodies
      - Others
    - By Service
      - Cell Line Engineering
      - gRNA Design
      - Microbial Gene Editing
      - DNA synthesis
  - Europe CRISPR and Cas Genes Market, By Application
    - Biomedical
      - Genome Engineering
      - Disease Model Studies
      - Functional Genomics
      - Epigenetics
      - Others
    - Agricultural
  - Europe CRISPR and Cas Genes Market, By End-use
    - Biotechnology & Pharmaceutical Companies
    - Academics & Government Research Institutes
    - Contract Research Organizations (CROs)
  - Germany
    - Germany CRISPR and Cas Genes Market, By Product & Service
      - By Product
        
        Kits & Enzymes
        
        Vector-based Cas9
        
        DNA-free Cas9
        
        Libraries
        
        Design Tool
        
        Antibodies
        
        Others
      - By Service
        
        Cell Line Engineering
        
        gRNA Design
        
        Microbial Gene Editing
        
        DNA synthesis
    - Germany CRISPR and Cas Genes Market, By Application
      - Biomedical
        
        Genome Engineering
        
        Disease Model Studies
        
        Functional Genomics
        
        Epigenetics
        
        Others
      - Agricultural
    - Germany CRISPR and Cas Genes Market, By End-use
      - Biotechnology & Pharmaceutical Companies
      - Academics & Government Research Institutes
      - Contract Research Organizations (CROs)
  - France
    - France CRISPR and Cas Genes Market, By Product & Service
      - By Product
        
        Kits & Enzymes
        
        Vector-based Cas9
        
        DNA-free Cas9
        
        Libraries
        
        Design Tool
        
        Antibodies
        
        Others
      - By Service
        
        Cell Line Engineering
        
        gRNA Design
        
        Microbial Gene Editing
        
        DNA synthesis
    - France CRISPR and Cas Genes Market, By Application
      - Biomedical
        
        Genome Engineering
        
        Disease Model Studies
        
        Functional Genomics
        
        Epigenetics
        
        Others
      - Agricultural
    - France CRISPR and Cas Genes Market, By End-use
      - Biotechnology & Pharmaceutical Companies
      - Academics & Government Research Institutes
      - Contract Research Organizations (CROs)
  - Italy
    - Italy CRISPR and Cas Genes Market, By Product & Service
      - By Product
        
        Kits & Enzymes
        
        Vector-based Cas9
        
        DNA-free Cas9
        
        Libraries
        
        Design Tool
        
        Antibodies
        
        Others
      - By Service
        
        Cell Line Engineering
        
        gRNA Design
        
        Microbial Gene Editing
        
        DNA synthesis
    - Italy CRISPR and Cas Genes Market, By Application
      - Biomedical
        
        Genome Engineering
        
        Disease Model Studies
        
        Functional Genomics
        
        Epigenetics
        
        Others
      - Agricultural
    - Italy CRISPR and Cas Genes Market, By End-use
      - Biotechnology & Pharmaceutical Companies
      - Academics & Government Research Institutes
      - Contract Research Organizations (CROs)
  - Spain
    - Spain CRISPR and Cas Genes Market, By Product & Service
      - By Product
        
        Kits & Enzymes
        
        Vector-based Cas9
        
        DNA-free Cas9
        
        Libraries
        
        Design Tool
        
        Antibodies
        
        Others
      - By Service
        
        Cell Line Engineering
        
        gRNA Design
        
        Microbial Gene Editing
        
        DNA synthesis
    - Spain CRISPR and Cas Genes Market, By Application
      - Biomedical
        
        Genome Engineering
        
        Disease Model Studies
        
        Functional Genomics
        
        Epigenetics
        
        Others
      - Agricultural
    - Spain CRISPR and Cas Genes Market, By End-use
      - Biotechnology & Pharmaceutical Companies
      - Academics & Government Research Institutes
      - Contract Research Organizations (CROs)
  - U.K.
    - U.K. CRISPR and Cas Genes Market, By Product & Service
      - By Product
        
        Kits & Enzymes
        
        Vector-based Cas9
        
        DNA-free Cas9
        
        Libraries
        
        Design Tool
        
        Antibodies
        
        Others
      - By Service
        
        Cell Line Engineering
        
        gRNA Design
        
        Microbial Gene Editing
        
        DNA synthesis
    - U.K. CRISPR and Cas Genes Market, By Application
      - Biomedical
        
        Genome Engineering
        
        Disease Model Studies
        
        Functional Genomics
        
        Epigenetics
        
        Others
      - Agricultural
    - U.K. CRISPR and Cas Genes Market, By End-use
      - Biotechnology & Pharmaceutical Companies
      - Academics & Government Research Institutes
      - Contract Research Organizations (CROs)
  - Denmark
    - Denmark CRISPR and Cas Genes Market, By Product & Service
      - By Product
        
        Kits & Enzymes
        
        Vector-based Cas9
        
        DNA-free Cas9
        
        Libraries
        
        Design Tool
        
        Antibodies
        
        Others
      - By Service
        
        Cell Line Engineering
        
        gRNA Design
        
        Microbial Gene Editing
        
        DNA synthesis
    - Denmark CRISPR and Cas Genes Market, By Application
      - Biomedical
        
        Genome Engineering
        
        Disease Model Studies
        
        Functional Genomics
        
        Epigenetics
        
        Others
      - Agricultural
    - Denmark CRISPR and Cas Genes Market, By End-use
      - Biotechnology & Pharmaceutical Companies
      - Academics & Government Research Institutes
      - Contract Research Organizations (CROs)
  - Sweden
    - Sweden CRISPR and Cas Genes Market, By Product & Service
      - By Product
        
        Kits & Enzymes
        
        Vector-based Cas9
        
        DNA-free Cas9
        
        Libraries
        
        Design Tool
        
        Antibodies
        
        Others
      - By Service
        
        Cell Line Engineering
        
        gRNA Design
        
        Microbial Gene Editing
        
        DNA synthesis
    - Sweden CRISPR and Cas Genes Market, By Application
      - Biomedical
        
        Genome Engineering
        
        Disease Model Studies
        
        Functional Genomics
        
        Epigenetics
        
        Others
      - Agricultural
    - Sweden CRISPR and Cas Genes Market, By End-use
      - Biotechnology & Pharmaceutical Companies
      - Academics & Government Research Institutes
      - Contract Research Organizations (CROs)
  - Norway
    - Norway CRISPR and Cas Genes Market, By Product & Service
      - By Product
        
        Kits & Enzymes
        
        Vector-based Cas9
        
        DNA-free Cas9
        
        Libraries
        
        Design Tool
        
        Antibodies
        
        Others
      - By Service
        
        Cell Line Engineering
        
        gRNA Design
        
        Microbial Gene Editing
        
        DNA synthesis
    - Norway CRISPR and Cas Genes Market, By Application
      - Biomedical
        
        Genome Engineering
        
        Disease Model Studies
        
        Functional Genomics
        
        Epigenetics
        
        Others
      - Agricultural
    - Norway CRISPR and Cas Genes Market, By End-use
      - Biotechnology & Pharmaceutical Companies
      - Academics & Government Research Institutes
      - Contract Research Organizations (CROs)
- Asia Pacific
- Latin America
  - Latin America CRISPR and Cas Genes Market, By Product & Service
    - By Product
      - Kits & Enzymes
        
        Vector-based Cas9
        
        DNA-free Cas9
      - Libraries
      - Design Tool
      - Antibodies
      - Others
    - By Service
      - Cell Line Engineering
      - gRNA Design
      - Microbial Gene Editing
      - DNA synthesis
  - Latin America CRISPR and Cas Genes Market, By Application
    - Biomedical
      - Genome Engineering
      - Disease Model Studies
      - Functional Genomics
      - Epigenetics
      - Others
    - Agricultural
  - Latin America CRISPR and Cas Genes Market, By End-use
    - Biotechnology & Pharmaceutical Companies
    - Academics & Government Research Institutes
    - Contract Research Organizations (CROs)
  - Brazil
    - Brazil CRISPR and Cas Genes Market, By Product & Service
      - By Product
        
        Kits & Enzymes
        
        Vector-based Cas9
        
        DNA-free Cas9
        
        Libraries
        
        Design Tool
        
        Antibodies
        
        Others
      - By Service
        
        Cell Line Engineering
        
        gRNA Design
        
        Microbial Gene Editing
        
        DNA synthesis
    - Brazil CRISPR and Cas Genes Market, By Application
      - Biomedical
        
        Genome Engineering
        
        Disease Model Studies
        
        Functional Genomics
        
        Epigenetics
        
        Others
      - Agricultural
    - Brazil CRISPR and Cas Genes Market, By End-use
      - Biotechnology & Pharmaceutical Companies
      - Academics & Government Research Institutes
      - Contract Research Organizations (CROs)
  - Mexico
    - Mexico CRISPR and Cas Genes Market, By Product & Service
      - By Product
        
        Kits & Enzymes
        
        Vector-based Cas9
        
        DNA-free Cas9
        
        Libraries
        
        Design Tool
        
        Antibodies
        
        Others
      - By Service
        
        Cell Line Engineering
        
        gRNA Design
        
        Microbial Gene Editing
        
        DNA synthesis
    - Mexico CRISPR and Cas Genes Market, By Application
      - Biomedical
        
        Genome Engineering
        
        Disease Model Studies
        
        Functional Genomics
        
        Epigenetics
        
        Others
      - Agricultural
    - Mexico CRISPR and Cas Genes Market, By End-use
      - Biotechnology & Pharmaceutical Companies
      - Academics & Government Research Institutes
      - Contract Research Organizations (CROs)
  - Argentina
    - Argentina CRISPR and Cas Genes Market, By Product & Service
      - By Product
        
        Kits & Enzymes
        
        Vector-based Cas9
        
        DNA-free Cas9
        
        Libraries
        
        Design Tool
        
        Antibodies
        
        Others
      - By Service
        
        Cell Line Engineering
        
        gRNA Design
        
        Microbial Gene Editing
        
        DNA synthesis
    - Argentina CRISPR and Cas Genes Market, By Application
      - Biomedical
        
        Genome Engineering
        
        Disease Model Studies
        
        Functional Genomics
        
        Epigenetics
        
        Others
      - Agricultural
    - Argentina CRISPR and Cas Genes Market, By End-use
      - Biotechnology & Pharmaceutical Companies
      - Academics & Government Research Institutes
      - Contract Research Organizations (CROs)
- Middle East & Africa

CRISPR And Cas Genes Market Dynamics

Driver: Rising adoption in the field of epigenetics

CRISPR and Cas genes enable targeted manipulation of epigenetic marks that help in studying the relationship between epigenomic and transcriptional control. They also allow precise control over cell phenotype. Increased use of CRISPR to shape epigenetic processes regulating gene expression is expected to fuel demand for the technology. Rise in the interest of bioresearches to study epigenetic processes and understand gene expression to gain insights into correlation with mental health, heart diseases, cancer, and the aging process pronounces epigenetics to play a critical role in solving major public health problems. Moreover, millions of epigenetic markers are identified that rely on statistical association with gene expression. The earlier known gene editing tools, i.e., ZFNs and TALENs could be used for deacetylation, demethylation, and histone methylation, but no method existed for target histone acetylation. Histone acetylation is strongly associated with regulatory and gene enhancer elements that can be efficiently targeted using CRISPR and Cas genes. Using this technology, researchers have gained unprecedented control over specific promotor or enhancer genes. Thus, increased adoption of CRISPR and Cas genes for gene enhancement and regulatory control in epigenetics is expected to boost market growth. Epigenome editing technologies exhibit significant potential for future R&D in chromatin biology and personalized medicine. Innovations and important breakthroughs in this area would help establish a solid foundation to advance human disease management.

Restraint: Off-target effects of CRISPR technology

Owing to its off-target effects, implementation of CRISPR technology is limited in clinical applications. Off-target effects in gene editing may lead to uncontrollable and unpredictable consequences in humans. These may affect transcription or gene functions that are desired to be imposed by CRISPR, thus limiting its applications for medicine and therapy in humans. Moreover, algorithms that can predict off-target effects such as one from MIT and one called E-CRISP, have failed to detect a significant number of off-target effects. Ongoing efforts to reduce these off-target effects such as modification, construction, design, and optimization of various elements involved in the procedure are expected to harness profits in the future.

Opportunity: Expanding cell & gene therapy space

Conventional genome editing technologies are not capable of keeping pace with the rapid progress of genome modification because these technologies are inefficient, time-consuming, and labor-intensive. Advent of CRISPR/Cas9 nuclease allows easy & precise genome editing. Being one of the primary applications of gene editing technologies, the gene and cell therapy arena would directly impact the use of CRISPR technology. A substantial number of cell and gene therapies are expected to be launched in the next 5 to 10 years. MIT NEWDIGS researchers estimated that around 40 gene therapies might have received approved by the end of 2022. In addition, several in-house facilities and CDMOs for gene therapy manufacturing have begun investing to enhance their production capacity, which in turn is anticipated to create lucrative opportunities for market players. For instance, FUJIFILM Diosynth Biotechnologies announced an expansion of its gene therapy manufacturing capacity at Texas in February 2020. Similarly, Thermo Fisher Scientific, Inc., in December 2019, established a 50,000 sq. ft. viral vector CDMO site in Lexington, Massachusetts.

What Does This Report Include?

This section will provide insights into the contents included in this CRISPR and cas genes market report and help gain clarity on the structure of the report to assist readers in navigating smoothly.

CRISPR and cas genes market qualitative analysis

Industry overview
Industry trends
Market drivers and restraints
Market size
Growth prospects
Porter’s analysis
PESTEL analysis
Key market opportunities prioritized
Competitive landscape
- Company overview
- Financial performance
- Product benchmarking
- Latest strategic developments

CRISPR and cas genes market quantitative analysis

Market size, estimates, and forecast from 2018 to 2030
Market estimates and forecast for product segments up to 2030
Regional market size and forecast for product segments up to 2030
Market estimates and forecast for application segments up to 2030
Regional market size and forecast for application segments up to 2030
Company financial performance

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