Chromatography resins are media used to capture and polish mAbs, antibody fragments, vaccines, and other biomolecules using a stationary phase. Chromatography resins can be categorized into two types:
Natural resins: These resins are extracted from plants. They comprise an ambiguous mixture of Carboxylic acids, essential oils, and isoprene-based hydrocarbons.
Rosins - It is derived from the pitch of pine trees.
Oleoresins - These resins contain the essential oils of plants.
Gum resins - They are the natural mixtures of true gum and resins including natural rubber, gamboge, myrrh, and olibanum.
Synthetic resins: Synthetics resins are produced polymerization involving the formation of chain-linked polymers.
The global chromatography resins market was valued at ~USD2 billion in 2020 and it is expected to grow at a CAGR of 7-8% from 2020 to 2027 due to increasing demand from the pharmaceutical sector, for drug discovery. The pharmaceutical sector is the largest end-user segment with more than 85% revenue share. The pharmaceutical industry extensively uses chromatography resins in inspecting and cleaning compounds to remove contamination. Natural resins are the leading product segment and they accounted for more than 50% of revenue share in the global chromatography resins market. North America is the largest geographic segment in the market with more than 30% revenue share. However, the shifting of production base to APAC by leading pharmaceutical companies is expected to bolster the growth rate of chromatography resins in the region during the forecast period.
The cost components of procuring natural resins and synthetic resins are different. Natural resins are typically extracted from trees like pines and firs. Hence, the processing cost plays a huge role in determining the cost of natural resin production. Whereas, synthetic resins are manufactured industrially via the process of polymerization with help of a chemically processed source of Naphtha, a residual part of crude oil. In this case, the cost of raw material is the key cost component of resin production. Synthetic resin production costs largely depend on the availability of raw materials and crude oil prices.
The Covid-19 pandemic has negatively affected the global chromatography resins industry in 2020. Many countries were forced to temporarily halt all types of industrial operations and restrict international trade during the pandemic. It created a supply shortage of raw materials for synthetic resins production. Moreover, regulations on using a limited number of laborers at production sites reduced the output in the last two years.
Exxon Mobil, Lyondell Basell, Dow Chemical, SABIC, INEOS, Merck KGaA, Bio-Rad Laboratories, Inc., Purolite, W. R. Grace & Co.-Conn., Mitsubishi Chemical Corporation, Danaher, are some of the key suppliers of chromatography resins. The global chromatography resin industry features a moderately consolidated landscape with leading players contributing around 65% of the market share. Industry leaders are strengthening their presence through multiple mergers and acquisitions. Grand View Research will help our client identify the best-suited suppliers by mapping their core capabilities and operational efficiency.
Component wise cost break down for better negotiation for the client, highlights the key cost drivers in the market with future price fluctuation for different materials (e.g.: steel, aluminum, etc.) used in the production process
Offering cost transparency for different products / services procured by the client. A typical report involves 2-3 case scenarios helping clients to select the best suited engagement with the supplier
Determining and forecasting salaries for specific skill set labor to make decision on outsourcing vs in-house.
A typical newsletter study by capturing latest information for specific suppliers related to: M&As, technological innovations, expansion, litigations, bankruptcy etc.
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