Hydrogel-based Drug Delivery System Market Worth $10.6 Billion By 2028

July 2021 | Report Format: Electronic (PDF)

Hydrogel-based Drug Delivery System Market Growth & Trends

The global hydrogel-based drug delivery system market size is anticipated to reach USD 10.6 billion by 2028, according to a new report by Grand View Research, Inc. The market is expected to expand at a CAGR of 7.5% from 2021 to 2028. Hydrogels help in achieving spatial and temporal control over the release of the incorporated drug. Therefore, the surging demand for controlled releases drug delivery system across many therapeutic areas is a key factor expected to contribute to market growth during the forecast period.

Hydrogel-based drug delivery systems deliver the therapeutic drug directly at the target site and in a sustained manner. This can leverage beneficial outcomes such as improved efficacy, reduced side effects, and decreased dosage for patients and formulators. Hydrogel-based drug delivery systems are appealing and have been used in many branches of medicine such as oncology, pain management, immunology, cardiology, and wound management.

The unique physical properties of hydrogel attract their interest in use for drug delivery applications. The porosity and drug loading capacity of hydrogels can be adjusted by modifying the density of cross-linking. This helps them to protect liable large drug molecules from degradation increasing the half-life. Many research studies have been carried out to examining the delivery of insulin orally using hydrogel systems. As patient compliance issues are frequently reported with injectable insulins such innovation is expected to be a disruptive technology in the diabetes care market.

There are numerous clinical studies underway specific to hydrogel-based drug delivery systems and various hydrogel technologies have already received regulatory approval for biomedical application. However, the technological challenges including the absence of defined regulatory guidelines, chemistry, complex manufacturing and control paraments, and practical adaptability are major roadblocks in the successful implementation in drug delivery use. For instance, the fabrication of hydrogel is complex and varies significantly depending upon the hydrogel systems.

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Hydrogel-based Drug Delivery System Market Report Highlights

  • Based on polymer origin, the synthetic segment held the largest proportion of market share in 2020

  • The hybrid segment is expected to witness the fastest growth rate over the forecast period owing to the development of stimuli-responsive hydrogel technology

  • The synthetic segment is anticipated to grow fast over the forecast period compared to natural hydrogels due to their high drug loading capacity and improved mechanical strength

  • Based on delivery route, the ocular segment accounted for the largest revenue share in 2020

  • The subcutaneous segment is expected to grow at a healthy rate over the forecast period owing to the increasing number of clinical and pre-clinical studies carried out

  • North America holds the largest revenue share in this market due to the presence of key companies in the region doing R&D on specific hydrogel-based drug delivery systems

  • In Asia Pacific, the market is expected to grow at the fastest rate over the forecast period due to large patient base, improving healthcare infrastructure, and surging demand for modern therapies

Hydrogel-based Drug Delivery System Market Segmentation

Grand View Research has segmented the global hydrogel-based drug delivery system market on the basis of polymer origin, delivery route, and region:

Hydrogel-based Drug Delivery System Polymer Origin Outlook (Revenue, USD Million, 2016 - 2028)

  • Natural

  • Synthetic

  • Hybrid

Hydrogel-based Drug Delivery System Delivery Route Outlook (Revenue, USD Million, 2016 - 2028)

  • Subcutaneous

  • Ocular

  • Oral Cavity

  • Topical

  • Other

Hydrogel-based Drug Delivery System Region Outlook (Revenue, USD Million, 2016 - 2028)

  • North America

    • U.S.

    • Canada

  • Europe

    • U.K.

    • Germany

    • France

    • Italy

    • Spain

  • Asia Pacific

    • China

    • Japan

    • India

    • Thailand

    • South Korea

  • Latin America

    • Brazil

    • Mexico

    • Argentina

  • Middle East & Africa

    • South Africa

    • Saudi Arabia

    • UAE

List of Key Players of Hydrogel-based Drug Delivery System Market


  • Blairex Laboratories, Inc.

  • Johnson & Johnson

  • Bausch and Lomb

  • Medtronic

  • Ocular Therapeutix, Inc.

  • Ferring B.V.

  • Endo International plc

  • Akorn, Incorporated

  • Tolmar Pharmaceuticals, Inc.

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