U.S. Cancer Immunotherapy Market Size & Outlook, 2026-2033
Related Markets
U.S. cancer immunotherapy market highlights
- The U.S. cancer immunotherapy market generated a revenue of USD 59,686.5 million in 2025 and is expected to reach USD 111,366.4 million by 2033.
- The U.S. market is expected to grow at a CAGR of 8.2% from 2026 to 2033.
- In terms of segment, monoclonal antibodies was the largest revenue generating product in 2025.
- Oncolytic Viral Therapies and Cancer Vaccines is the most lucrative product segment registering the fastest growth during the forecast period.
Cancer immunotherapy market data book summary
| Market revenue in 2025 | USD 59,686.5 million |
| Market revenue in 2033 | USD 111,366.4 million |
| Growth rate | 8.2% (CAGR from 2026 to 2033) |
| Largest segment | Monoclonal antibodies |
| Fastest growing segment | Oncolytic Viral Therapies and Cancer Vaccines |
| Historical data | 2021 - 2024 |
| Base year | 2025 |
| Forecast period | 2026 - 2033 |
| Quantitative units | Revenue in USD million |
| Market segmentation | Monoclonal Antibodies, Check Point Inhibitors, Oncolytic Viral Therapies and Cancer Vaccines |
| Key market players worldwide | Pfizer Inc, AstraZeneca PLC, Merck & Co Inc, Roche Holding AG, Bristol-Myers Squibb Co, Novartis AG ADR, Eli Lilly and Co, Johnson & Johnson, Immunocore Holdings PLC ADR |
Other key industry trends
- In terms of revenue, U.S. accounted for 38.9% of the global cancer immunotherapy market in 2025.
- Country-wise, U.S. is expected to lead the global market in terms of revenue in 2033.
- In North America, U.S. cancer immunotherapy market is projected to lead the regional market in terms of revenue in 2033.
- Mexico is the fastest growing regional market in North America and is projected to reach USD 4,412.2 million by 2033.
Monoclonal antibodies was the largest segment with a revenue share of 63.08% in 2025. Horizon Databook has segmented the U.S. cancer immunotherapy market based on monoclonal antibodies, check point inhibitors, oncolytic viral therapies and cancer vaccines covering the revenue growth of each sub-segment from 2021 to 2033.
Cancer immunotherapy market in the U.S. is driven primarily by the high incidence of cancer, advancements in medical science, increased funding for R&D in oncology, high consumer awareness, and proactive government initiatives. Some of the latest market trends in cancer immunotherapy in the U.S., in 2019, were.
Checkpoint immunotherapy raising the long-term survival bar: for instance, combination of CTLA-4 and PD-1 inhibitor has shown double response rate than PD-1 monotherapy in liver cancer. Introduction of immunotherapy in the earlier stages of treatment can yield better results: for instance, PD-1 immunotherapy, in combination with chemotherapy, can double the survival rate when used as first-line.
No credit card required*
Horizon in a snapshot
- 30K+ Global Market Reports
- 120K+ Country Reports
- 1.2M+ Market Statistics
- 200K+ Company Profiles
- Industry insights and more
Cancer Immunotherapy Market Scope
Cancer Immunotherapy Market Companies
| Name | Profile | # Employees | HQ | Website |
|---|---|---|---|---|
| Immunocore Holdings PLC ADR | View profile | 497 | 92 Park Drive, Milton Park, Abingdon, Oxfordshire, United Kingdom, OX14 4RY | https://www.immunocore.com |
| AstraZeneca PLC | View profile | 89900 | 1 Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge, United Kingdom, CB2 0AA | https://www.astrazeneca.com |
| Eli Lilly and Co | View profile | 43000 | Lilly Corporate Center, Indianapolis, IN, United States, 46285 | https://www.lilly.com |
| Bristol-Myers Squibb Co | View profile | 34100 | Route 206 and Province Line Road, Princeton, New Jersey, NJ, United States, 08543 | https://www.bms.com |
| Merck & Co Inc | View profile | 72000 | 126 East Lincoln Avenue, Rahway, NJ, United States, 07065 | https://www.merck.com |
| Roche Holding AG | View profile | 103605 | Grenzacherstrasse 124, Basel, Switzerland, 4070 | https://www.roche.com |
| Pfizer Inc | View profile | 88000 | 66 Hudson Boulevard East, New York, NY, United States, 10001-2192 | https://www.pfizer.com |
| Novartis AG ADR | View profile | 76057 | Lichtstrasse 35, Basel, Switzerland, 4056 | https://www.novartis.com |
| Johnson & Johnson | View profile | 134400 | One Johnson and Johnson Plaza, New Brunswick, NJ, United States, 08933 | https://www.jnj.com |
U.S. cancer immunotherapy market size, by product, 2021-2033 (US$M)
U.S. Cancer Immunotherapy Market Outlook Share, 2025 & 2033 (US$M)
Related industry reports
Related statistics
No records
No related statistics found.
Sign up - it's easy, and free!
Sign up and get instant basic access to databook, upgrade
when ready, or enjoy our
free plan indefinitely.
Included in Horizon account
- 30K+ Global Market Reports
- 120K+ Country Reports
- 1.2M+ Market Statistics
- 200K+ Company Profiles
- Industry insights and more
