North America Glp-1 Agonists Weight Loss Drugs Market Size & Outlook

The glp-1 agonists weight loss drugs market in North America is expected to reach a projected revenue of US$ 38,813.6 million by 2030. A compound annual growth rate of 19.2% is expected of North America glp-1 agonists weight loss drugs market from 2025 to 2030.
Revenue, 2024 (US$M)
$10,451.7
Forecast, 2030 (US$M)
$38,813.6
CAGR, 2025 - 2030
19.2%
Report Coverage
North America

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North America glp-1 agonists weight loss drugs market, 2018-2030 (US$M)

North America glp-1 agonists weight loss drugs market, 2018-2030 (US$M)

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Related Markets

North America glp-1 agonists weight loss drugs market highlights

  • The North America glp-1 agonists weight loss drugs market generated a revenue of USD 10,451.7 million in 2024.
  • The market is expected to grow at a CAGR of 19.2% from 2025 to 2030.
  • In terms of segment, semaglutide (wegovy) was the largest revenue generating drug in 2024.
  • Tirzepatide (Zepbound) is the most lucrative drug segment registering the fastest growth during the forecast period.
  • Country-wise, U.S. is expected to register the highest CAGR from 2025 to 2030.


North America data book summary

Market revenue in 2024USD 10,451.7 million
Market revenue in 2030USD 38,813.6 million
Growth rate19.2% (CAGR from 2025 to 2030)
Largest segmentSemaglutide (wegovy)
Fastest growing segmentTirzepatide (Zepbound)
Historical data covered2018 - 2023
Base year for estimation2024
Forecast period covered2025 - 2030
Quantitative unitsRevenue in USD million
Market segmentationSemaglutide (Wegovy), Liraglutide (Saxenda), Tirzepatide (Zepbound), Other Drugs


Other key industry trends

  • In terms of revenue, North America region accounted for 75.5% of the global glp-1 agonists weight loss drugs market in 2024.
  • Globally, North America is projected to lead the regional market in terms of revenue in 2030.
  • North America is the fastest growing regional market and is projected to reach USD 38,813.6 million by 2030.

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GLP-1 Agonists Weight Loss Drugs Market Companies

Name Profile # Employees HQ Website
Eli Lilly and Company View profile - - -
Structure Therapeutics View profile 101-250 South San Francisco, California, United States, North America https://structuretx.com/
Viking Therapeutics Inc View profile 28 9920 Pacific Heights Boulevard, Suite 350, San Diego, CA, United States, 92121 https://www.vikingtherapeutics.com
Novo Nordisk A/S ADR View profile 66015 Novo Alle 1, Bagsvaerd, Denmark, 2880 https://www.novonordisk.com
Pfizer Inc View profile 88000 66 Hudson Boulevard East, New York, NY, United States, 10001-2192 https://www.pfizer.com

North America glp-1 agonists weight loss drugs market outlook

The databook is designed to serve as a comprehensive guide to navigating this sector. The databook focuses on market statistics denoted in the form of revenue and y-o-y growth and CAGR across the globe and regions. A detailed competitive and opportunity analyses related to glp-1 agonists weight loss drugs market will help companies and investors design strategic landscapes.


Semaglutide (wegovy) was the largest segment with a revenue share of 93.15% in 2024. Horizon Databook has segmented the North America glp-1 agonists weight loss drugs market based on semaglutide (wegovy), liraglutide (saxenda), tirzepatide (zepbound), other drugs covering the revenue growth of each sub-segment from 2018 to 2030.


North America dominated the GLP-1 agonists weight loss drugs market with the largest revenue share of 75.50% in 2024. 

Driven by the increasing prevalence of obesity and related conditions, the demand for GLP-1 agonists, such as Semaglutide (Wegovy), Liraglutide (Saxenda), and Tirzepatide (Zepbound), is rising. 

The market is also benefiting from a shift toward more accessible treatment options, with both parenteral and oral formulations available in retail and hospital pharmacies.

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Horizon Databook provides a detailed overview of continent-level data and insights on the North America glp-1 agonists weight loss drugs market , including forecasts for subscribers. This continent databook contains high-level insights into North America glp-1 agonists weight loss drugs market from 2018 to 2030, including revenue numbers, major trends, and company profiles.

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North America glp-1 agonists weight loss drugs market size, by country, 2018-2030 (US$M)

North America GLP-1 Agonists Weight Loss Drugs Market Outlook Share, 2024 & 2030 (US$M)

North America glp-1 agonists weight loss drugs market size, by country, 2018-2030 (US$M)

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