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U.S. Long Read Sequencing Market Size & Outlook, 2026-2033

The long read sequencing market in the United States is expected to reach a projected revenue of US$ 1,302.6 million by 2033. A compound annual growth rate of 21.44% is expected of the United States long read sequencing market from 2026 to 2033.

  • Biotechnology
    • Sequencing technology
      • Long Read Sequencing Market Outlook
Revenue, 2025 (US$M)
$284.6
Estimate, 2026 (US$M)
$334.4
Forecast, 2033 (US$M)
$1,302.6
CAGR, 2026 - 2033
21.4%
U.S. Long Read Sequencing Market, 2021-2033 (US$M)

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Every figure cited from GVR research

U.S. long read sequencing market highlights

  • The U.S. long read sequencing market generated a revenue of USD 284.6 million in 2025 and is expected to reach USD 1,302.6 million by 2033.
  • The U.S. market is expected to grow at a CAGR of 21.44% from 2026 to 2033.
  • In terms of segment, sequencing was the largest revenue generating workflow in 2025.
  • Data Analysis is the most lucrative workflow segment registering the fastest growth during the forecast period.


Long read sequencing market data book summary

Market revenue in 2025USD 284.6 million
Market revenue in 2033USD 1,302.6 million
Growth rate21.44% (CAGR from 2026 to 2033)
Largest segmentSequencing
Fastest growing segmentData Analysis
Historical data2021 - 2024
Base year2025
Forecast period2026 - 2033
Quantitative unitsRevenue in USD million
Market segmentationData Analysis, Pre-sequencing, Sequencing
Key market players worldwidePacific Biosciences of California Inc, Oxford Nanopore Technologies PLC, Eurofins Scientific SE, Roche Holding AG ADR, New England Biolabs, Huawei Technologies, BGI Group, Quantapore, Element Biosciences, MicrobesNG


Other key industry trends

  • In terms of revenue, U.S. accounted for 46.5% of the global long read sequencing market in 2025.
  • Country-wise, U.S. is expected to lead the global market in terms of revenue in 2033.
  • In North America, U.S. long read sequencing market is projected to lead the regional market in terms of revenue in 2033.
  • Canada is the fastest growing regional market in North America and is projected to reach USD 127.7 million by 2033.

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Publish Date: Jul 01, 2026

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Long Read Sequencing Market Companies

NameProfile# EmployeesHQWebsite
Roche Holding AG ADRView profile 103,605Grenzacherstrasse 124, Basel, Switzerland, 4070www.roche.com
Eurofins Scientific SEView profile 61,79823 Val Fleuri, Luxembourg, Luxembourg, L-1526www.eurofins.com
New England BiolabsView profile 501-1000Ipswich, Massachusetts, United States, North Americaneb.com
Pacific Biosciences of California IncView profile 7961305 O’Brien Drive, Menlo Park, CA, United States, 94025www.pacb.com
Huawei TechnologiesView profile 10001+Shenzhen, Guangdong, China, Asiahuawei.com
Oxford Nanopore Technologies PLCView profile 1,133Edmund Halley Road, Gosling Building, Oxford Science Park, Oxford, Oxfordshire, United Kingdom, OX4 4DQwww.nanoporetech.com
BGI GroupView profile 5001-10000Shenzhen, Guangdong, China, Asiawww.genomics.cn/
QuantaporeView profile 1-10Menlo Park, California, United States, North Americawww.quantapore.com/
Element BiosciencesView profile 251-500San Diego, California, United States, North Americawww.elementbiosciences.com
MicrobesNGView profile 11-50Birmingham, Birmingham, United Kingdom, Europemicrobesng.com

U.S. Long Read Sequencing Market Outlook

The databook is designed to serve as a comprehensive guide to navigating this sector. The databook focuses on market statistics denoted in the form of revenue and y-o-y growth and CAGR across the globe and regions. A detailed competitive and opportunity analyses related to Long Read Sequencing Market Outlook will help companies and investors design strategic landscapes.


Sequencing was the largest segment with a revenue share of 73.37% in 2025.

Horizon Databook has segmented the U.S. long read sequencing market based on data analysis, pre-sequencing, sequencing covering the revenue growth of each sub-segment from 2021 to 2033.


  • U.S. Long Read Sequencing Market Workflow Outlook (Revenue, USD Million , 2021-2033)
    • Pre-sequencing
    • Data Analysis
    • Sequencing
  • U.S. Long Read Sequencing Market Product Outlook (Revenue, USD Million , 2021-2033)
    • Instruments
    • Consumables
    • Services
  • U.S. Long Read Sequencing Market End Use Outlook (Revenue, USD Million , 2021-2033)
    • Academic & Research Institutes
    • Pharmaceutical & Biotechnology Companies
    • Hospitals & Clinics
    • Others
  • U.S. Long Read Sequencing Market Technology Outlook (Revenue, USD Million , 2021-2033)
    • Nanopore Sequencing
    • Single Molecule Real Time Sequencing
    • Others
  • U.S. Long Read Sequencing Market Application Outlook (Revenue, USD Million , 2021-2033)
    • Whole Genome Sequencing
    • Targeted Sequencing
    • Metagenomics
    • Others
    • RNA Sequencing
    • Epigenetics

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  • Our clientele includes a mix of Long Read Sequencing Market Outlook companies, investment firms, advisory firms & academic institutions.
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  • Approximately 65% of our revenue is generated working with competitive intelligence & market intelligence teams of market participants (manufacturers, service providers, etc.).
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Horizon Databook provides a detailed overview of country-level data and insights on the U.S. Long Read Sequencing Market Outlook, including forecasts for subscribers. This country databook contains high-level insights into U.S. Long Read Sequencing Market Outlook from 2021 to 2033, including revenue numbers, major trends, and company profiles.

U.S. Long Read Sequencing Market, 2021-2033 (US$M)

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US Workflow - Long Read Sequencing Market Statistics, 2025 - 2033 (US$M)

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US Workflow - Long Read Sequencing Market Statistics, 2025 - 2033 (USD Million)

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