U.S. Semaglutide Market Size & Outlook, 2024-2035
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U.S. semaglutide market highlights
- The U.S. semaglutide market generated a revenue of USD 19,826.5 million in 2024 and is expected to reach USD 57,964.7 million by 2035.
- The U.S. market is expected to grow at a CAGR of 9.5% from 2025 to 2035.
- In terms of segment, ozempic (semaglutide) was the largest revenue generating product in 2024.
- Ozempic (semaglutide) is the most lucrative product segment registering the fastest growth during the forecast period.
Semaglutide market data book summary
| Market revenue in 2024 | USD 19,826.5 million |
| Market revenue in 2035 | USD 57,964.7 million |
| Growth rate | 9.5% (CAGR from 2025 to 2035) |
| Largest segment | Ozempic (semaglutide) |
| Fastest growing segment | Ozempic (semaglutide) |
| Historical data | 2018 - 2023 |
| Base year | 2024 |
| Forecast period | 2025 - 2035 |
| Quantitative units | Revenue in USD million |
| Market segmentation | Ozempic (semaglutide), Wegovy (semaglutide), Rybelsus (oral semaglutide) |
Other key industry trends
- In terms of revenue, U.S. accounted for 69.7% of the global semaglutide market in 2024.
- Country-wise, U.S. is expected to lead the global market in terms of revenue in 2035.
- In North America, U.S. semaglutide market is projected to lead the regional market in terms of revenue in 2035.
- Mexico is the fastest growing regional market in North America and is projected to reach USD 629.4 million by 2035.
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Semaglutide Market Scope
Semaglutide Market Companies
| Name | Profile | # Employees | HQ | Website |
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U.S. semaglutide market outlook
The databook is designed to serve as a comprehensive guide to navigating this sector. The databook focuses on market statistics denoted in the form of revenue and y-o-y growth and CAGR across the globe and regions. A detailed competitive and opportunity analyses related to semaglutide market will help companies and investors design strategic landscapes.
Ozempic (semaglutide) was the largest segment with a revenue share of 69.99% in 2024. Horizon Databook has segmented the U.S. semaglutide market based on ozempic (semaglutide), wegovy (semaglutide), rybelsus (oral semaglutide) covering the revenue growth of each sub-segment from 2018 to 2035.
The U.S. dominates the North America semaglutide market, driven by increasing demand for GLP-1 receptor agonists in diabetes and obesity management. Early regulatory approvals, and extensive R&D activities contribute to market expansion.
The rising adoption of semaglutide for weight loss, despite its primary approval for diabetes, is reshaping prescribing trends. Retail pharmacies are the dominant distribution channel, with online pharmacies gaining traction due to convenience and direct-to-consumer models.
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Target buyers of U.S. semaglutide market databook
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Our clientele includes a mix of semaglutide market companies, investment firms, advisory firms & academic institutions.
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30% of our revenue is generated working with investment firms and helping them identify viable opportunity areas.
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Approximately 65% of our revenue is generated working with competitive intelligence & market intelligence teams of market participants (manufacturers, service providers, etc.).
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The rest of the revenue is generated working with academic and research not-for-profit institutes. We do our bit of pro-bono by working with these institutions at subsidized rates.
Horizon Databook provides a detailed overview of country-level data and insights on the U.S. semaglutide market , including forecasts for subscribers. This country databook contains high-level insights into U.S. semaglutide market from 2018 to 2035, including revenue numbers, major trends, and company profiles.
Partial client list
US Product - Semaglutide Market size, 2024 - 2035 (US$M)
U.S. Semaglutide Market Outlook Share, 2024 & 2035 (US$M)
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