South Africa Vaccine Market Size & Outlook, 2026-2033
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South Africa vaccine market highlights
- The South Africa vaccine market generated a revenue of USD 344.1 million in 2025 and is expected to reach USD 528.3 million by 2033.
- The South Africa market is expected to grow at a CAGR of 5.3% from 2026 to 2033.
- In terms of segment, viral vaccines was the largest revenue generating indication in 2025.
- Other Indication is the most lucrative indication segment registering the fastest growth during the forecast period.
Vaccine market data book summary
| Market revenue in 2025 | USD 344.1 million |
| Market revenue in 2033 | USD 528.3 million |
| Growth rate | 5.3% (CAGR from 2026 to 2033) |
| Largest segment | Viral vaccines |
| Fastest growing segment | Other Indication |
| Historical data | 2021 - 2024 |
| Base year | 2025 |
| Forecast period | 2026 - 2033 |
| Quantitative units | Revenue in USD million |
| Market segmentation | Viral Vaccines, Bacterial Vaccines, Cancer Vaccines, Allergy Vaccines, Other Indication |
| Key market players worldwide | Serum Institute of India Pvt. Ltd., CSL Ltd, Sanofi SA, GSK PLC, Merck & Co Inc, Pfizer Inc, Sinovac Biotech Ltd, BioNTech SE ADR, AstraZeneca PLC, Moderna Inc |
Other key industry trends
- In terms of revenue, South Africa accounted for 0.5% of the global vaccine market in 2025.
- Country-wise, U.S. is expected to lead the global market in terms of revenue in 2033.
- In Middle East & Africa, Saudi Arabia vaccine market is projected to lead the regional market in terms of revenue in 2033.
- Kuwait is the fastest growing regional market in Middle East & Africa and is projected to reach USD 411.4 million by 2033.
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Vaccine Market Scope
Vaccine Market Companies
| Name | Profile | # Employees | HQ | Website |
|---|---|---|---|---|
| Moderna Inc | View profile | 5600 | 200 Technology Square, Cambridge, MA, United States, 02139 | https://www.modernatx.com |
| BioNTech SE ADR | View profile | 6133 | An der Goldgrube 12, Mainz, RP, Germany, D-55131 | https://www.biontech.de |
| CSL Ltd | View profile | 32000 | 655 Elizabeth Street, Melbourne, VIC, Australia, 3000 | https://www.csl.com |
| Sinovac Biotech Ltd | View profile | 3261 | No.39, Shangdi Xi Road, Haidan District, Beijing, China, People's Republic of, 100085 | http://www.sinovac.com |
| AstraZeneca PLC | View profile | 89900 | 1 Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge, United Kingdom, CB2 0AA | https://www.astrazeneca.com |
| Serum Institute of India Pvt. Ltd. | View profile | 1001-5000 | Pune, Maharashtra, India, Asia | http://www.seruminstitute.com/ |
| GSK PLC | View profile | 70200 | 980 Great West Road, Brentford, Middlesex, United Kingdom, TW8 9GS | https://www.gsk.com |
| Merck & Co Inc | View profile | 72000 | 126 East Lincoln Avenue, Rahway, NJ, United States, 07065 | https://www.merck.com |
| Sanofi SA | View profile | 87994 | 46, avenue de la Grande Armée, Paris, France, 75017 | https://www.sanofi.com |
| Pfizer Inc | View profile | 88000 | 66 Hudson Boulevard East, New York, NY, United States, 10001-2192 | https://www.pfizer.com |
South Africa vaccine market outlook
The databook is designed to serve as a comprehensive guide to navigating this sector. The databook focuses on market statistics denoted in the form of revenue and y-o-y growth and CAGR across the globe and regions. A detailed competitive and opportunity analyses related to vaccine market will help companies and investors design strategic landscapes.
Viral vaccines was the largest segment with a revenue share of 65.94% in 2025. Horizon Databook has segmented the South Africa vaccine market based on viral vaccines, bacterial vaccines, cancer vaccines, allergy vaccines, other indication covering the revenue growth of each sub-segment from 2021 to 2033.
Human (seasonal) influenza viruses are regarded as a global public health threat, causing significant morbidity and mortality in low- & middle-income countries each year, with sub-Saharan Africa witnessing high mortality rates.
The high prevalence of comorbidities in South Africa, such as HIV, tuberculosis, and other noncommunicable chronic diseases, which are associated with an increased risk of severe influenza, intensifies the health & economic burden of seasonal influenza.
This initiative, aimed at promoting South Africa's COVID-19 vaccination campaign, will assist the government in effectively managing the pandemic, especially as the country confronts its fifth wave. Furthermore, the project seeks to empower the GoSA to enhance its health system through the creation of a fiscal room and the establishment of financial & institutional sustainability.
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Target buyers of South Africa vaccine market databook
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Our clientele includes a mix of vaccine market companies, investment firms, advisory firms & academic institutions.
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30% of our revenue is generated working with investment firms and helping them identify viable opportunity areas.
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Approximately 65% of our revenue is generated working with competitive intelligence & market intelligence teams of market participants (manufacturers, service providers, etc.).
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The rest of the revenue is generated working with academic and research not-for-profit institutes. We do our bit of pro-bono by working with these institutions at subsidized rates.
Horizon Databook provides a detailed overview of country-level data and insights on the South Africa vaccine market , including forecasts for subscribers. This country databook contains high-level insights into South Africa vaccine market from 2021 to 2033, including revenue numbers, major trends, and company profiles.
Partial client list
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