U.S. Bone Grafts And Substitutes Market Size & Outlook

The bone grafts and substitutes market in the United States is expected to reach a projected revenue of US$ 1,405.1 million by 2030. A compound annual growth rate of 6.1% is expected of the United States bone grafts and substitutes market from 2025 to 2030.
Revenue, 2024 (US$M)
$993.6
Forecast, 2030 (US$M)
$1,405.1
CAGR, 2025 - 2030
6.1%
Report Coverage
U.S.

U.S. bone grafts and substitutes market, 2018-2030 (US$M)

U.S.

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U.S. bone grafts and substitutes market highlights

  • The U.S. bone grafts and substitutes market generated a revenue of USD 993.6 million in 2024 and is expected to reach USD 1,405.1 million by 2030.
  • The U.S. market is expected to grow at a CAGR of 6.1% from 2025 to 2030.
  • In terms of segment, allograft was the largest revenue generating material type in 2024.
  • Synthetic is the most lucrative material type segment registering the fastest growth during the forecast period.

Bone grafts and substitutes market data book summary

Market revenue in 2024USD 993.6 million
Market revenue in 2030USD 1,405.1 million
Growth rate6.1% (CAGR from 2025 to 2030)
Largest segmentAllograft
Fastest growing segmentSynthetic
Historical data2018 - 2023
Base year2024
Forecast period2025 - 2030
Quantitative unitsRevenue in USD million
Market segmentationAllograft, Synthetic
Key market players worldwideDePuy Synthes, Baxter International Inc, NuVasive, Smith & Nephew PLC, Medtronic PLC, Orthofix Medical Inc, Zimmer Biomet Holdings Inc, Geistlich Pharma, Stryker Corp, AlloSource, TBF, OST Laboratoires, Biobank

Other key industry trends

  • In terms of revenue, U.S. accounted for 31.5% of the global bone grafts and substitutes market in 2024.
  • Country-wise, U.S. is expected to lead the global market in terms of revenue in 2030.
  • In North America, U.S. bone grafts and substitutes market is projected to lead the regional market in terms of revenue in 2030.
  • Mexico is the fastest growing regional market in North America and is projected to reach USD 61.8 million by 2030.

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Bone Grafts And Substitutes Market Companies

Name Profile # Employees HQ Website

U.S. bone grafts and substitutes market outlook

The databook is designed to serve as a comprehensive guide to navigating this sector. The databook focuses on market statistics denoted in the form of revenue and y-o-y growth and CAGR across the globe and regions. A detailed competitive and opportunity analyses related to bone grafts and substitutes market will help companies and investors design strategic landscapes.


Allograft was the largest segment with a revenue share of 63.26% in 2024. Horizon Databook has segmented the U.S. bone grafts and substitutes market based on allograft, synthetic covering the revenue growth of each sub-segment from 2018 to 2030.


The U.S. bone graft and substitutes market growth can be majorly attributed to a large number of orthopedic procedures being performed due to the increase in the incidence of orthopedic diseases and traumatic injuries.

Hence, the growing incidence of diabetes and arthritis is likely to increase the demand for surgeries. Moreover, developments by key players are expected to boost market growth with huge untapped opportunities.

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  • 30% of our revenue is generated working with investment firms and helping them identify viable opportunity areas.
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Horizon Databook provides a detailed overview of country-level data and insights on the U.S. bone grafts and substitutes market , including forecasts for subscribers. This country databook contains high-level insights into U.S. bone grafts and substitutes market from 2018 to 2030, including revenue numbers, major trends, and company profiles.

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U.S. bone grafts and substitutes market

U.S. Bone Grafts And Substitutes Market Outlook Share, 2024 & 2030 (US$M)

U.S. bone grafts and substitutes market

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