South Africa Glp-1 Receptor Agonist Market Size & Outlook
Global Market
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South Africa glp-1 receptor agonist market highlights
- The South Africa glp-1 receptor agonist market generated a revenue of USD 119.1 million in 2025 and is expected to reach USD 344.3 million by 2033.
- The South Africa market is expected to grow at a CAGR of 13.3% from 2026 to 2033.
- In terms of segment, semaglutide (ozempic, wegovy, rybelsus) was the largest revenue generating product in 2025.
- Tirzepatide (Mounjaro, Zepbound) is the most lucrative product segment registering the fastest growth during the forecast period.
Glp-1 receptor agonist market data book summary
| Market revenue in 2025 | USD 119.1 million |
| Market revenue in 2033 | USD 344.3 million |
| Growth rate | 13.3% (CAGR from 2026 to 2033) |
| Largest segment | Semaglutide (ozempic, wegovy, rybelsus) |
| Fastest growing segment | Tirzepatide (Mounjaro, Zepbound) |
| Historical data | 2021 - 2024 |
| Base year | 2025 |
| Forecast period | 2026 - 2033 |
| Quantitative units | Revenue in USD million |
| Market segmentation | Semaglutide (Ozempic, Wegovy, Rybelsus), Tirzepatide (Mounjaro, Zepbound), Dulaglutide (Trulicity), Liraglutide (Victoza, Saxenda), Others (Byetta, Bydureon, SOLIQUA) |
| Key market players worldwide | Eli Lilly and Co, Sanofi SA, Novo Nordisk A/S ADR, AstraZeneca PLC |
Other key industry trends
- In terms of revenue, South Africa accounted for 0.2% of the global glp-1 receptor agonist market in 2025.
- Country-wise, U.S. is expected to lead the global market in terms of revenue in 2033.
- In Middle East & Africa, Saudi Arabia glp-1 receptor agonist market is projected to lead the regional market in terms of revenue in 2033.
- Saudi Arabia is the fastest growing regional market in Middle East & Africa and is projected to reach USD 1,248.1 million by 2033.
In comparison with other regions, Africa has a greater overall incidence of target diseases, and there is no evidence that this prevalence has decreased recently. According to an article published by the University of Pretoria, in March 2024, South Africa has over 4 million people with diabetes and many of the existing patient population are not getting proper treatment.
In addition, the obesity rate in the country is around 11% in male and 41% in female further increasing the risk of diabetes. Moreover, technological developments have triggered the evolution of the pharmaceutical industry in the region. However, the issue of investments arises when private companies try setting up pharmaceutical production in the country.
Key players in the country are undertaking several initiatives to enhance therapeutics in the market. For instance, in January 2022, Novo Nordisk launched once weekly semaglutide to treat type 2 diabetes. The prevalence of diabetes is expected to be highest in South Africa, and the key players operating in the market are constantly focused on developing and commercializing GLP-1 receptor agonist in the country to meet the increasing demand.
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Publish Date: Dec 23, 2025
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GLP-1 Receptor Agonist Market Scope
GLP-1 Receptor Agonist Market Companies
| Name | Profile | # Employees | HQ | Website |
|---|---|---|---|---|
| Teva Pharmaceutical Industries Ltd | View profile | 37,851 | 124 Dvora HaNevi’a Street, Tel Aviv, Israel, 6944020 | www.tevapharm.com |
| Sanofi SA | View profile | 87,994 | 46, avenue de la Grande Armée, Paris, France, 75017 | www.sanofi.com |
| Eli Lilly and Co | View profile | 43,000 | Lilly Corporate Center, Indianapolis, IN, United States, 46285 | www.lilly.com |
| Novo Nordisk A/S ADR | View profile | 66,015 | Novo Alle 1, Bagsvaerd, Denmark, 2880 | www.novonordisk.com |
| AstraZeneca PLC | View profile | 89,900 | 1 Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge, United Kingdom, CB2 0AA | www.astrazeneca.com |
| Glenmark Pharmaceuticals | View profile | 10001+ | Andheri, Maharashtra, India, Asia | www.glenmarkpharma.com |
South Africa GLP-1 Receptor Agonist Market Outlook
The databook is designed to serve as a comprehensive guide to navigating this sector. The databook focuses on market statistics denoted in the form of revenue and y-o-y growth and CAGR across the globe and regions. A detailed competitive and opportunity analyses related to GLP-1 Receptor Agonist Market Outlook will help companies and investors design strategic landscapes.
Semaglutide (Ozempic, Wegovy, Rybelsus) was the largest segment with a revenue share of 68.43% in 2025.
Horizon Databook has segmented the South Africa glp-1 receptor agonist market based on semaglutide (ozempic, wegovy, rybelsus), tirzepatide (mounjaro, zepbound), dulaglutide (trulicity), liraglutide (victoza, saxenda), others (byetta, bydureon, soliqua) covering the revenue growth of each sub-segment from 2021 to 2033.
In comparison with other regions, Africa has a greater overall incidence of target diseases, and there is no evidence that this prevalence has decreased recently. According to an article published by the University of Pretoria, in March 2024, South Africa has over 4 million people with diabetes and many of the existing patient population are not getting proper treatment.
In addition, the obesity rate in the country is around 11% in male and 41% in female further increasing the risk of diabetes. Moreover, technological developments have triggered the evolution of the pharmaceutical industry in the region. However, the issue of investments arises when private companies try setting up pharmaceutical production in the country.
Key players in the country are undertaking several initiatives to enhance therapeutics in the market. For instance, in January 2022, Novo Nordisk launched once weekly semaglutide to treat type 2 diabetes. The prevalence of diabetes is expected to be highest in South Africa, and the key players operating in the market are constantly focused on developing and commercializing GLP-1 receptor agonist in the country to meet the increasing demand.
- South Africa Glp-1 Receptor Agonist Market Product Outlook (Revenue, USD Million , 2021-2033)
- Semaglutide (Ozempic, Wegovy, Rybelsus)
- Tirzepatide (Mounjaro, Zepbound)
- Dulaglutide (Trulicity)
- Liraglutide (Victoza, Saxenda)
- Others (Byetta, Bydureon, SOLIQUA)
- South Africa Glp-1 Receptor Agonist Market Application Outlook (Revenue, USD Million , 2021-2033)
- Type 2 Diabetes Mellitus
- Obesity / Chronic Weight Management
- Cardiovascular Risk
- South Africa Glp-1 Receptor Agonist Market Route of Administration Outlook (Revenue, USD Million , 2021-2033)
- Injectable / Parenteral
- Oral
- South Africa Glp-1 Receptor Agonist Market Distribution Channel Outlook (Revenue, USD Million , 2021-2033)
- Hospital Pharmacies
- Retail Pharmacies
- Online Pharmacies
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Horizon Databook provides a detailed overview of country-level data and insights on the South Africa GLP-1 Receptor Agonist Market Outlook, including forecasts for subscribers. This country databook contains high-level insights into South Africa GLP-1 Receptor Agonist Market Outlook from 2021 to 2033, including revenue numbers, major trends, and company profiles.
South Africa Glp-1 Receptor Agonist Market, 2021-2033 (US$M)
South Africa glp-1 receptor agonist market statistics, by product, 2021-2033 (US$M)
