North America Liquid Biopsy Market Size & Outlook, 2025-2033
- Clinical Diagnostics
- In Vitro Diagnostics
- Liquid Biopsy Market Outlook
- In Vitro Diagnostics
Global Market
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North America liquid biopsy market highlights
- The North America liquid biopsy market generated a revenue of USD 6,934.0 million in 2025.
- The market is expected to grow at a CAGR of 11.1% from 2026 to 2033.
- In terms of segment, blood sample based was the largest revenue generating sample type in 2025.
- Blood Sample Based is the most lucrative sample type segment registering the fastest growth during the forecast period.
- Country-wise, Mexico is expected to register the highest CAGR from 2026 to 2033.
North America data book summary
| Market revenue in 2025 | USD 6,934.0 million |
| Market revenue in 2033 | USD 16,171.3 million |
| Growth rate | 11.1% (CAGR from 2026 to 2033) |
| Largest segment | Blood sample based |
| Fastest growing segment | Blood Sample Based |
| Historical data covered | 2021 - 2024 |
| Base year for estimation | 2025 |
| Forecast period covered | 2026 - 2033 |
| Quantitative units | Revenue in USD million |
| Market segmentation | Blood Sample Based |
| Key market players worldwide | ANGLE PLC, Guardant Health Inc, Myriad Genetics Inc, Biocept Inc, Lucence Health, Roche, Qiagen NV, Illumina Inc, Thermo Fisher Scientific Inc, Epigenomics AG, Oncimmune, Freenome |
Other key industry trends
- In terms of revenue, North America region accounted for 51.0% of the global liquid biopsy market in 2025.
- Globally, North America is projected to lead the regional market in terms of revenue in 2033.
- Asia Pacific is the fastest growing regional market and is projected to reach USD 5,298.2 million by 2033.
North America leads the global liquid biopsy market in terms of revenue generation, owing to high cancer prevalence, rapid technological advancements, and growing government initiatives.
The North America market is led by the U.S. owing to greater investments and presence of several biotechnology companies developing advanced tests. Various organizations, such as American Society of Clinical Oncology, are engaged in supporting the implementation of liquid biopsy, which is likely to boost revenue in this market.
A rise in the number of approvals of new diagnostic tests is anticipated to fuel the market growth further in the near future. For instance, in July 2022, Nanostics, Inc. announced the launch of a clinical investigation for bladder cancer to identify the most effective indicators of the disease for early detection.
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Publish Date: Jun 16, 2026
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Liquid Biopsy Market Scope
Liquid Biopsy Market Companies
| Name | Profile | # Employees | HQ | Website |
|---|---|---|---|---|
| Thermo Fisher Scientific Inc | View profile | 122,000 | 168 Third Avenue, Waltham, MA, United States, 02451 | www.thermofisher.com |
| Illumina Inc | View profile | 9,300 | 5200 Illumina Way, San Diego, CA, United States, 92122 | www.illumina.com |
| Qiagen NV | View profile | 5,900 | Hulsterweg 82, Venlo, LI, Netherlands, 5912 PL | www.qiagen.com |
| ANGLE PLC | View profile | 165 | 10 Nugent Road, The Surrey Research Park, Surrey, Guildford, United Kingdom, GU2 7AF | www.angleplc.com |
| Myriad Genetics Inc | View profile | 2,700 | 320 Wakara Way, Salt Lake City, UT, United States, 84108 | www.myriad.com |
| Biocept Inc | View profile | 50 | 9955 Mesa Rim Road, San Diego, CA, United States, 92121 | www.biocept.com |
| Guardant Health Inc | View profile | 1,779 | 3100 Hanover Street, Palo Alto, CA, United States, 94304 | www.guardanthealth.com |
| Epigenomics AG | View profile | 18 | Geneststrasse 5, Berlin, BB, Germany, 10829 | www.epigenomics.com |
| Roche | View profile | 10001+ | Basel, Basel-Stadt, Switzerland, Europe | www.roche.com |
| Lucence Health | View profile | 51-100 | Palo Alto, California, United States, North America | www.lucence.com/ |
North America Liquid Biopsy Market Outlook
The databook is designed to serve as a comprehensive guide to navigating this sector. The databook focuses on market statistics denoted in the form of revenue and y-o-y growth and CAGR across the globe and regions. A detailed competitive and opportunity analyses related to Liquid Biopsy Market Outlook will help companies and investors design strategic landscapes.
Blood Sample Based was the largest segment with a revenue share of 80.69% in 2025.
Horizon Databook has segmented the North America liquid biopsy market based on blood sample based covering the revenue growth of each sub-segment from 2021 to 2033.
North America leads the global liquid biopsy market in terms of revenue generation, owing to high cancer prevalence, rapid technological advancements, and growing government initiatives.
The North America market is led by the U.S. owing to greater investments and presence of several biotechnology companies developing advanced tests. Various organizations, such as American Society of Clinical Oncology, are engaged in supporting the implementation of liquid biopsy, which is likely to boost revenue in this market.
A rise in the number of approvals of new diagnostic tests is anticipated to fuel the market growth further in the near future. For instance, in July 2022, Nanostics, Inc. announced the launch of a clinical investigation for bladder cancer to identify the most effective indicators of the disease for early detection.
- North America Liquid Biopsy Market Sample Type Outlook (Revenue, USD Million , 2021-2033)
- Blood Sample Based
- Others
- North America Liquid Biopsy Market Biomarker Outlook (Revenue, USD Million , 2021-2033)
- Circulating Nucleic Acids
- CTC
- Exosomes/Microvesicles
- Circulating Proteins
- North America Liquid Biopsy Market Technology Outlook (Revenue, USD Million , 2021-2033)
- Multi-gene-parallel Analysis (NGS)
- Single Gene Analysis (PCR Microarrays)
- North America Liquid Biopsy Market Application Outlook (Revenue, USD Million , 2021-2033)
- Cancer
- Reproductive Health
- Others
- North America Liquid Biopsy Market End Use Outlook (Revenue, USD Million , 2021-2033)
- Hospitals and Laboratories
- Specialty Clinics
- Academic and Research Centers
- Others
- North America Liquid Biopsy Market Clinical Application Outlook (Revenue, USD Million , 2021-2033)
- Therapy Selection
- Treatment Monitoring
- Early Cancer Screening
- Recurrence Monitoring
- Others
- North America Liquid Biopsy Market Product Outlook (Revenue, USD Million , 2021-2033)
- Instruments
- Consumables Kits and Reagents
- Software and Services
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Horizon Databook provides a detailed overview of continent-level data and insights on the North America Liquid Biopsy Market Outlook, including forecasts for subscribers. This continent databook contains high-level insights into North America Liquid Biopsy Market Outlook from 2021 to 2033, including revenue numbers, major trends, and company profiles.
North America Liquid Biopsy Market, 2021-2033 (US$M)
North America Sample Type - Liquid Biopsy Market Statistics, 2024 - 2033 (US$M)
