U.S. Liquid Biopsy Market Size & Outlook, 2024-2030

The liquid biopsy market in the United States is expected to reach a projected revenue of US$ 9,561.4 million by 2030. A compound annual growth rate of 11.4% is expected of the United States liquid biopsy market from 2025 to 2030.
Revenue, 2024 (US$M)
$4,980.2
Forecast, 2030 (US$M)
$9,561.4
CAGR, 2025 - 2030
11.4%
Report Coverage
U.S.

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U.S. liquid biopsy market, 2018-2030 (US$M)

U.S. liquid biopsy market, 2018-2030 (US$M)

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U.S. liquid biopsy market highlights

  • The U.S. liquid biopsy market generated a revenue of USD 4,980.2 million in 2024 and is expected to reach USD 9,561.4 million by 2030.
  • The U.S. market is expected to grow at a CAGR of 11.4% from 2025 to 2030.
  • In terms of segment, blood sample based was the largest revenue generating type in 2024.
  • Blood Sample Based is the most lucrative type segment registering the fastest growth during the forecast period.

Liquid biopsy market data book summary

Market revenue in 2024USD 4,980.2 million
Market revenue in 2030USD 9,561.4 million
Growth rate11.4% (CAGR from 2025 to 2030)
Largest segmentBlood sample based
Fastest growing segmentBlood Sample Based
Historical data2018 - 2023
Base year2024
Forecast period2025 - 2030
Quantitative unitsRevenue in USD million
Market segmentationBlood Sample Based
Key market players worldwideANGLE PLC, Guardant Health Inc, Myriad Genetics Inc, Biocept Inc, Lucence Health, Roche, Qiagen NV, Illumina Inc, Thermo Fisher Scientific Inc, Epigenomics AG, Oncimmune, Freenome

Other key industry trends

  • In terms of revenue, U.S. accounted for 42.0% of the global liquid biopsy market in 2024.
  • Country-wise, U.S. is expected to lead the global market in terms of revenue in 2030.
  • In North America, U.S. liquid biopsy market is projected to lead the regional market in terms of revenue in 2030.
  • Mexico is the fastest growing regional market in North America and is projected to reach USD 132.3 million by 2030.

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Liquid Biopsy Market Scope

Liquid biopsy market segmentation & scope
Blood Sample Based
Others
Circulating Nucleic Acids
CTC
Exosomes/Microvesicles
Circulating Proteins
Multi-gene-parallel Analysis (NGS)
Single Gene Analysis (PCR Microarrays)
Lung Cancer
Prostate Cancer
Breast Cancer
Colorectal Cancer
Leukemia
Gastrointestinal Cancer
Others
Reproductive Health
Others
Hospitals and Laboratories
Specialty Clinics
Academic and Research Centers
Others
Therapy Selection
Treatment Monitoring
Early Cancer Screening
Recurrence Monitoring
Others
Instruments
Consumables Kits and Reagents
Software and Services

Liquid Biopsy Market Companies

Name Profile # Employees HQ Website

U.S. liquid biopsy market outlook

The databook is designed to serve as a comprehensive guide to navigating this sector. The databook focuses on market statistics denoted in the form of revenue and y-o-y growth and CAGR across the globe and regions. A detailed competitive and opportunity analyses related to liquid biopsy market will help companies and investors design strategic landscapes.


Blood sample based was the largest segment with a revenue share of 81.31% in 2024. Horizon Databook has segmented the U.S. liquid biopsy market based on blood sample based covering the revenue growth of each sub-segment from 2018 to 2030.


The U.S. accounted for the major revenue share of the liquid biopsy market in 2023. Rapid technological advancements, recent FDA approvals for liquid biopsy tests, and intense competition between companies are expected to boost market growth over the forecast period.

According to the American Cancer Society, in 2021, 235,760 people are estimated to be diagnosed with non-small cell lung cancer, the most common form of lung cancer in the U.S. Overall, around 1 in 17 men and 1 in 15 women are at risk of developing lung cancer in their lifetime.

Roche's cobas liquid biopsy test was approved for use in patients with non-small cell lung cancer to identify specific genetic mutations in the tumor. Moreover, the launch of novel diagnostics solutions is expected to propel the market further.

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Target buyers of U.S. liquid biopsy market databook

  • Our clientele includes a mix of liquid biopsy market companies, investment firms, advisory firms & academic institutions.
  • 30% of our revenue is generated working with investment firms and helping them identify viable opportunity areas.
  • Approximately 65% of our revenue is generated working with competitive intelligence & market intelligence teams of market participants (manufacturers, service providers, etc.).
  • The rest of the revenue is generated working with academic and research not-for-profit institutes. We do our bit of pro-bono by working with these institutions at subsidized rates.

Horizon Databook provides a detailed overview of country-level data and insights on the U.S. liquid biopsy market , including forecasts for subscribers. This country databook contains high-level insights into U.S. liquid biopsy market from 2018 to 2030, including revenue numbers, major trends, and company profiles.

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U.S. liquid biopsy market size, by type, 2018-2030 (US$M)

U.S. Liquid Biopsy Market Outlook Share, 2024 & 2030 (US$M)

U.S. liquid biopsy market size, by type, 2018-2030 (US$M)

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