North America Pulmonary Arterial Hypertension Market Size & Outlook

The pulmonary arterial hypertension market in North America is expected to reach a projected revenue of US$ 4,504.4 million by 2030. A compound annual growth rate of 5.1% is expected of North America pulmonary arterial hypertension market from 2025 to 2030.
Revenue, 2024 (US$M)
$3,356.1
Forecast, 2030 (US$M)
$4,504.4
CAGR, 2025 - 2030
5.1%
Report Coverage
North America

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North America pulmonary arterial hypertension market, 2018-2030 (US$M)

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North America pulmonary arterial hypertension market highlights

  • The North America pulmonary arterial hypertension market generated a revenue of USD 3,356.1 million in 2024.
  • The market is expected to grow at a CAGR of 5.1% from 2025 to 2030.
  • In terms of segment, prostacyclin and prostacyclin analogs was the largest revenue generating drug class in 2024.
  • SGC Stimulators is the most lucrative drug class segment registering the fastest growth during the forecast period.
  • Country-wise, Canada is expected to register the highest CAGR from 2025 to 2030.


North America data book summary

Market revenue in 2024USD 3,356.1 million
Market revenue in 2030USD 4,504.4 million
Growth rate5.1% (CAGR from 2025 to 2030)
Largest segmentProstacyclin and prostacyclin analogs
Fastest growing segmentSGC Stimulators
Historical data covered2018 - 2023
Base year for estimation2024
Forecast period covered2025 - 2030
Quantitative unitsRevenue in USD million
Market segmentationEndothelin Receptor Antagonists (ERAs), PDE-5 Inhibitors, Prostacyclin and Prostacyclin Analogs, SGC Stimulators
Key market players worldwideUnited Therapeutics Corp, Bayer AG, Gilead Sciences Inc, Johnson & Johnson, Viatris Inc, GlaxoSmithKline, Sandoz Group AG ADR, Lupin, Sun Pharmaceutical Industries, Teva Pharmaceutical Industries Ltd


Other key industry trends

  • In terms of revenue, North America region accounted for 41.8% of the global pulmonary arterial hypertension market in 2024.
  • Globally, North America is projected to lead the regional market in terms of revenue in 2030.
  • Asia Pacific is the fastest growing regional market and is projected to reach USD 1,530.9 million by 2030.

Prostacyclin and prostacyclin analogs was the largest segment with a revenue share of 49.2% in 2024. Horizon Databook has segmented the North America pulmonary arterial hypertension market based on endothelin receptor antagonists (eras), pde-5 inhibitors, prostacyclin and prostacyclin analogs, sgc stimulators covering the revenue growth of each sub-segment from 2018 to 2030.


North America accounted for largest share about 57.7% of global PAH market in 2020. Developed healthcare infrastructure in U.S. enabled access to advanced therapeutics which contributed to the growth of this region. Moreover, availability of reimbursement on PAH therapies supported the growth of North American PAH market.

Growing awareness, high diagnosis rate and supportive government initiatives governed the growth of this region. Sedentary lifestyle habits such as smoking, alcohol and junk food are vital risk factors for development of PAH.

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Pulmonary Arterial Hypertension Market Companies

Name Profile # Employees HQ Website
Sandoz Group AG ADR View profile - - -
GlaxoSmithKline View profile 10001+ London, England, United Kingdom, Europe http://www.gsk.com
United Therapeutics Corp View profile 1168 1000 Spring Street, Silver Spring, MD, United States, 20910 https://www.unither.com
Viatris Inc View profile 38000 1000 Mylan Boulevard, Canonsburg, PA, United States, 15317 https://www.viatris.com
Gilead Sciences Inc View profile 18000 333 Lakeside Drive, Foster, CA, United States, 94404 https://www.gilead.com
Sun Pharmaceutical Industries View profile 10001+ Mumbai, Maharashtra, India, Asia http://www.sunpharma.com
Bayer AG View profile 99723 Kaiser-Wilhelm-Allee 1, Leverkusen, NW, Germany, 51368 https://www.bayer.com
Lupin View profile 10001+ Mumbai, Maharashtra, India, Asia https://www.lupin.com
Teva Pharmaceutical Industries Ltd View profile 37851 124 Dvora HaNevi’a Street, Tel Aviv, Israel, 6944020 https://www.tevapharm.com
Johnson & Johnson View profile 134400 One Johnson and Johnson Plaza, New Brunswick, NJ, United States, 08933 https://www.jnj.com

North America pulmonary arterial hypertension market size, by country, 2018-2030 (US$M)

North America Pulmonary Arterial Hypertension Market Outlook Share, 2024 & 2030 (US$M)

North America pulmonary arterial hypertension market size, by country, 2018-2030 (US$M)

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