Downstream Process Development: Evolving Trend to Shape Bioseparation Systems for Commercial Biotechnology

Posted On Sep, 22, 2017

In the current scenario, technological advancement in large-scale downstream bioprocessing systems is an ever-increasing trend in biotechnology. Popularity of single-use bioprocessing instruments, advancements in existing separation & purification techniques are expected to drive growth in the near future. Rising demand for biopharmaceuticals, increasing partnerships, M&A activities, and R&D investments are also expected to boost the market in the near future.

Recent developments in therapeutic recombinant proteins is driving growth

Development of new and advanced therapeutics is creating lucrative demand for separation and purification systems. Developments, such as HBs-Ag produced by heterologous expression in yeasts in France & the U.S. and FDA approval for the first inhaling insulin powder for diabetes patients in 2015 are anticipated to propel growth.

Currently, researchers are developing recombinant fusion protein markers for infectious diseases. Scientists are working on recognizing the effect of host cell protein during recombinant protein production. Identification of toxic materials and their reduction remains a major point of concern.

Moreover, investigators are also focusing on characterization and identification of cold active enzymes for commercial applications in food processing. These efforts and innovations are likely to create growth opportunities for upstream bioprocessing systems in the coming years.

Waste recycling drives advancements in bioseparation systems

Economic development, coupled with rapid urbanization in developing countries, is driving the sector for efficient water management solutions. Industrialization has created the need for large-scale separation systems for wastewater recycling, which is anticipated to be the key driver for growth.

Moreover, strict environmental regulations for water used for food & pharmaceutical production is also expected to influence advancements in this sector. Programs, such as nonrevenue water & zero liquid discharge, are promoting development of technologically advanced instruments for water treatment.

Furthermore, entities are developing novel wastewater treatment technologies to eliminate contaminants from wastewater. This is another major factor expected to boost growth of commercial stage bioseparators in the coming years.

Competitive outlook

Private players are forming strategic alliances to introduce innovations in existing separation technologies. These players are extensively investing in R&D and developing advanced separator systems. For instance, in March 2015, Alfa Laval launched Culturefuge, a hermetic cell culture separation system that is designed to gently harvest shear-sensitive organisms in applications such as precipitated proteins and mammalian cell cultures.

  In-depth report on global separation systems for commercial biotechnology market by Grand View Research:

http://www.grandviewresearch.com/industry-analysis/separation-systems-for-commercial-biotechnology-market

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