Bioactive coatings on metallic implants facilitate joining between the prosthesis and the osseous tissue, and increase the long-term stability and integrity of the implant. These are thin films coated on medical devices to deter bacterial adhesion, improve core functionality of the device, and impart bioactivity along with biocompatibility to the device. One of the earliest successful bioactive coatings was that of heparin-modified surface of a polymer blood oxygenator component trademarked as Caemeda Affinity Blood Oxygenator, Trillium Affinity NT Blood Oxygenator, which received FDA approval.
Increasing number of bioactive coating medical devices used for surgeries and medical device implants are the major driver for the bioactive materials for coating.
Implantable devices containing thin films of bioactive molecules are rapidly gaining adoption in therapeutic areas of cardiology and orthopedic joint diseases – the two major sources of loss of quality of life and disability currently. Bioactive molecules and generic factors such as increasing incidence of systemic joint diseases, cardiovascular implant and support are driving the demand for bioactive coating devices across the globe. On the other hand, lack of research awareness, high requirement for funding for continued research, and less-developed research infrastructure in middle and low income countries among others are the restraints of market.
The global market for bioactive coating devices is segmented on the basis of product type, by medical application, by material, and by end-user.
On the basis of product type, the global market is classified into Anti-microbial coatings- also termed as self-fertilizing coatings. Antimicrobial coatings on textiles prevent the degradation of textile fibers, limit the incidence of bacteria, reduce the formation of odor following the microbial degradation of perspiration, and protect users by avoiding the transfer and spread of pathogens.
Hydrophilic coatings- This coating can be applied to many instruments such as catheters, canulas, and guidewires to prevent or at the very least reduce the amount of damage and inflammation they cause when being used on a patient.
Drug Eluting coating- They are statistically superior to bare-metal stents for the treatment of native coronary artery narrowings., and others (including Anti-thrombogenic coatings). Antimicrobial coatings are expected to grow gradually during the forecast period from 2014 to 2025 with maximum market share.
On the basis of medical application, the global market is classified into Stents, Cardiac assist devices, Electrosurgical tools, Cochlear and ocular implants, Mandrels and molds, Catheters, Elastomeric seals, Needles and epidural probes, Medical electronics. Metallic implants coated in hydroxyapatite have successfully been used in dental and orthopedic applications due to their well-documented promotion of direct bone apposition and osteoconductive properties.
On the basis of material, the global market is classified into Biological Materials, Carbon-Based Materials, Metals and Alloys, Polymers and Synthetic. This segment is projected to grow globally during forecast period.
On the basis of end-user, the global market is classified into Hospital, Diagnostics Centers, Ambulatory Surgical Centers, and Clinics. In the healthcare industry, hydroxyapatite has been widely used as a coating material to combine its sound biological properties with excellent mechanical properties of traditional metallic implant materials. Hospital end-user segment is projected to account for maximum market share due to requirement of advanced healthcare infrastructure and surgical devices.
Geographically, the global market is segmented into regions namely North America, Latin America, Western Europe, Eastern Europe, Asia Pacific, Japan, Middle East and Africa. North America accounts for the largest share in bioactive coating devices market due to high purchasing power. Asia Pacific is expected to account for the second largest share in global market due to low grade medical devices that get affected by the highly concentrated chemical, adulteration in metals used to prepare medical devices, and less developed research infrastructure.
The major key players of Bioactive Coating Market are as follows:
DSM Biomedical, Hydromer Inc., SurModics Inc., Biocoat Inc., AST Products Inc., Specialty Coatings Systems Inc., and others.
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