The G-protein coupled receptors (GPCRs) market is expected to witness a lucrative growth during the forecast period owing to the major factors such as increasing demand of GPCRs in ADME toxicity studies and drug discovery processes and ongoing patent expiration of blockbuster drug molecules.
Increasing prevalence of chronic lifestyle disorders such as breast cancer, cardiovascular diseases and respiratory disorders is leading to higher demand for newer and better treatment alternatives. G-protein coupled receptors (GPCRs) are very useful in the research and development of newer drug entities. Moreover, increasing government expenditure in research and developments such as biosensors, orphan drug receptors, drug targets and high-throughput screening techniques is also expected to drive the market growth.
Furthermore, structural and functional literatures on the pharmacological features of the GPCRs are showing that these GPCRs targets have versatile utilities in the treatment of a broad spectrum of diseases. Ongoing developments in the range of therapeutics for treatment of neurobiological, inflammation, pain and various other disorders are expected to boost the market growth in the near future. Moreover, rising application of G-protein coupled receptors in drug discovery & development processes are expected to fuel the market growth.
G-protein coupled receptors (GPCRs) market is segmented on the bases of types of assay and therapeutic area. GPCR assay types are further segmented into reporter gene assays, cGMP assays, GTPγS binding assays, cAMP assays, receptor internalization assays, and calcium level detection assays.
The cAMP assays segment was one of the largest markets in 2014 owing to the factors such as rising demand of these assays in major drug discovery platforms & high throughput screening (HTS) techniques. Increasing applications of these assays in cancer therapeutic areas is also driving the growth of this segment.
However, receptor gene assays are expected to witness a significant growth rate during the forecast period. This growth is attributed by the advantages such as high accuracy, large signal-to-background ratio, wide sensitivity and linearity offered by these assays.
Based on therapeutic area, the G-protein coupled receptors market is segmented into Central Nervous System (CNS), immune system, respiratory system, reproductive system, oncology, cardiovascular system, abdominal, and urinary system.
Oncology segment in the therapeutic G-protein coupled receptors market accounted for the largest market share in the year, 2014 due to one of the major factors such as increasing use of GPCRs in the identification and treatment of tumours. Central Nervous System (CNS) segment is expected to be the fastest growing segment in the coming years due to increasing research and development for G-protein coupled receptors in the treatment and diagnosis of central nervous system disorders.
Furthermore, advantages of GPCRs such as GPCR membrane preparations along with endogenous or recombinant receptors and adenosine transporter helps in the initial ligand identification and screening studies is one of the factors that are expected to drive demand for GPCR market during the forecast period.
Geographically, G-Protein coupled receptors market is segmented into North America, Europe, Asia-Pacific, Latin America and MEA. In 2014, North America accounted for the largest market share in terms of revenue due to the increasing application of G-protein coupled assays and receptors in cancer research, rising awareness & demand for innovative and advanced therapeutics and higher government expenditure after research & development.
Furthermore, introduction of advanced instrumentations such as label free biosensor based cellular assay platforms and novel drug discoveries are expected to drive the demand for G-protein coupled receptors market in the upcoming years.
Asia Pacific region is expected to grow at a significant rate during the forecast period owing to the economic development of the countries such as China and India owing to increasing government investment in the biotechnology and biopharmaceutical sector, increasing life expectancy, rising per capita income and unmet market needs in the region.
The key participants in the G-protein coupled receptors market include QIAGEN N.V., EMD (Merck) Millipore, HD Biosciences Co. Ltd, Cisbio Bioassays, Enzo Life Sciences Inc., Sigma-Aldrich Corporation, DiscoveRx Corporation, Promega Corporation, PerkinElmer Inc., Abcam plc, Thermo Fisher Scientific Inc. and Becton-Dickinson and Company.
Mergers & Acquisitions and licensing deals for the R&D activities is the current trend observed amongst the players dealing with the G-protein coupled receptors (GPCRs) market. This factor shows the attractiveness for new entrants in the G-protein coupled receptors (GPCRs) industry.
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