The global small animal imaging (In-vivo) market was valued at over USD 1.1 billion in 2012. Growing use of multi-functional preclinical imaging, rising investments of Clinical Research Organizations (CROs) in preclinical studies, increasing the number of pharmaceutical & research organizations, and technical innovations such as high-resolution MRI with other imaging modalities are some of the key market driving factors.
Stringent government regulations, inadequate reimbursements, accuracy, and the high cost of the devices are key market challenges. Small animal imaging (in-vivo) devices have emerged as a promising solution for the diagnoses of a variety of disease conditions found in laboratory animals. A wide range such devices are used in various domains such as cancer cell research, monitoring the drug response during drug development, assessing the bio-distribution patterns of new chemical entities, and biomarker research in animal models, in longitudinal studies, and others.
Different types of in-vivo imaging modalities are used in small animal imaging operations. The report elaborates the competitive advantages of advanced modalities over conventional alternatives. These devices are gaining importance and find applications in epigenetic research studies, receptor targeting, and defining the mechanism of action.
North America small animal imaging (in-vivo) market, by technology, 2012-2022, (USD Million)
Various technologies are in operation for this market. Research scientists from different disciplines such as biomedical engineering, chemistry, medicine and pharmacology, cell biology, genetics, and mathematics started their work towards improvements of imaging probes, devices, different assays, and quantification technologies to explicate the molecular mechanisms in medicines and biologics.
The aim of molecular imaging is to characterize, visualize, and quantify pathological and normal biological activities in the living organisms at cellular and sub-cellular levels using noninvasive methods.
The technology segment of this market includes micro-MRI, optical, nuclear, and others (micro-ultrasound and micro-CT). The optical segment is the largest revenue generating technology, which was valued at over USD 500 million in 2012.
The growth of this segment is attributed to its easy and rapid operations, and relatively lower costs as compared to other modalities. Micro-MRI technology segment is having the highest growth rate of around 11% over the analysis period. Such high growth rate is attributed to the specific and precise operations of micro-MRI modality in preclinical research.
The application segment of the small animal imaging (In-vivo) market includes monitoring treatment response, bio-distribution, cancer cell detection, biomarkers, longitudinal studies, and epigenetic studies segments. Bio-distribution and monitoring the treatment response are the two largest application segments. Bio-distribution segment generated the market share of over 30% in 2012, highest among all applications.
Preclinical bio-distribution or drug-target engagement assessment of new chemical entities is valuable in determining the drug efficacy to optimize drug formulations and find favorable profiles. Noninvasive near-infrared (NIR) fluorescence imaging allocates visualization, detection, and qualification in the full body tissue bio-distribution of the newly invented drug in real-time.
However, the cancer cell detection segment would show prominent growth rate owing to the rising global prevalence of cancer, which would generate research opportunities in the cancer cell detection application segment. Cancer cell detection application is expected to capture the market share of around 26% by 2022.
The geographical segmentation of small animal imaging (In-vivo) market includes North America, Europe, Asia-Pacific, and RoW. North America is the largest revenue generating regional market with over USD 420 million in 2012 and dominates the global market. Market growth in this region is mainly a reflection of novel imaging device innovations resulting from technological advances. High market share is also attributed to vast preclinical research in North America. Europe is the second largest market due to a large number of pharmaceutical and clinical research organizations and diagnostic device manufacturers.
Asia-Pacific region has the highest CAGR of around 11% among the geographic segments over the forecast period. Such high growth rate is attributed to the transition of clinical research activities from developed to developing economies.
Competitive Market Share Insights
Key players involved in the small animal imaging (in-vivo) market are also adopting the product launch and acquisition strategy to expand their business horizon, products, services, and geographic presence. The expansion was another growth strategy adopted by the players to enhance their geographic and product reach. Some of the key players mentioned in the report are Thermo Fisher Scientific, Promega Corporation, Inc., Mediso Medical Imaging Systems, Miltenyi Biotec GmbH, FujiFilm Holding Corporation, Bruker Corporation, PerkinElmer Inc., Aspect Imaging Ltd., Siemens AG, and Life Technologies Corporation.
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