Structural Biology & Molecular Modeling Techniques Market Report

Structural Biology & Molecular Modeling Techniques Market Analysis By Tools (SaaS & Standalone Modeling, Homology Modeling, Threading, Molecular Dynamics, Ab Initio, Visualization & Analysis, Databases), By Application, And Segment Forecasts, 2014 - 2025

Published: January 2017  |  95 Pages  |  Format: PDF  |  Report ID: GVR-1-68038-737-7

Industry Insights

The global structural biology & molecular modeling techniques market accounted for USD 2.52 billion in 2015 and is expected to grow at a CAGR of 18.2% over the coming years. The market is predominantly driven by rise in the prevalence of chronic diseases with acquired drug resistance that exemplifies the need for new and advanced therapeutics.

This has resulted in the high clinical urgency to incorporate structural biology & molecular modeling techniques to develop a new generation of drugs. For instance, in 2011, researchers from the University of Natural Resources and Life Sciences in Austria carried out molecular dynamics simulations to study the activity of humanized antibodies (Ab2/3H6), which is believed to neutralize HIV-1. The results generated through this simulation successfully identified back mutation sites in antibodies to enable antibody immunization without the loss of specificity and binding affinity in them.

U.S. structural biology & molecular modeling techniques market, by tools, 2014 - 2025 (USD Million)

U.S. structural biology & molecular modeling techniques market

In addition, the high drug attrition rate associated with late-phase clinical trials in drug development is a significant contributor of the elevated costs, which is further presumed to propel the demand for modeling techniques to reduce the probability of drug failure. This is achieved through the utilization of prediction software that provides detailed insights of proteins with 3-D molecular structures and predicts their binding conformation & biological interactions.

The emergence of technological innovations has led to the development of validated mathematical models that enable the determination of accurate structures and predict cellular functions & interactions, which aid in the identification of novel leads with greater chances. For instance, potency determination of new drug molecules through in silico screening of 3-D chemical structures expedite the lead discovery and optimization process, thereby allowing greater focus to be laid on targets with high therapeutic potential.

Moreover, advancements in, in silico drug designing tools coupled with the implementation of a multidisciplinary approach involving, computational biology, molecular biology, and biophysics, are resulting in novel methods that facilitate structural biologists in understanding diverse protein sequences and predicting protein structures accurately. These novel solutions are believed to enhance biomedical research and help address challenges, thereby optimizing the drug discovery process and boosting the demand for modeling tools.

Tools Insights

In 2015, SaaS & standalone modeling software accounted for the largest share of the tools segment. The substantial share attained by this segment is believed to be a consequence of the increasing number of computer-aided predictive procedures in structural biology that are to serve the market with significant growth opportunities during the forecast period.

In addition, assistance of sophisticated molecular modeling software has led to consistent development in research; hence wide-ranging applications in varied medical disciplines are presenting greater opportunities for this sector. Furthermore, growing adoption of this software by research professionals to analyze dock libraries and protein homology is expected to positively reinforce market growth during the forecast period.

Application Insights

Drug discovery is expected to witness a lucrative CAGR during the forecast period. This unprecedented growth rate can be attributed to the associated benefits of molecular modeling in drug discovery. The benefits facilitate researchers and structural biologists to identify critical gaps that restrict the drug discovery process, thereby yielding a relatively reduced drug attrition rate.

The high potential growth prospects can be attributed to probable incorporation of structural biology & molecular modeling techniques in pharmacogenetics and pharmacogenomics, contributing toward growth of the drug discovery segment. In addition, high clinical urgency to develop drugs for their use in conditions, such as pregnancy, where several drugs cannot be administered, is one of the key growth factors presumed to drive the segment. Moreover, rising number of structural prediction models to study physiological and biochemical changes are anticipated to provide a high potential growth platform to the market.

Regional Insights

In 2015, North America captured a dominant share of the overall structural biology & molecular modeling techniques market. Several collaborations undertaken by prominent market players toward heightening their R&D capabilities to ensure high medical standards is expected to propel the demand in this region. For instance, the American Diabetes Association introduced a research forum in collaboration with Entelos, Inc. to develop new treatment alternatives for Type 1 Diabetes through drug development simulation processes.

The Asia Pacific structural biology & molecular modeling techniques is expected to witness the fastest CAGR during the forecast period owing to the rising presence of contract research organizations, increasing healthcare IT spending, and unprecedented evolution of the healthcare infrastructure and standards.

Global structural biology & molecular modeling techniques market share, by application, 2015

Global structural biology & molecular modeling techniques market

Competitive Insights

This industry is predicted to exhibit intense competition over the coming years due to the increasing adoption of collaborative strategies amongst the market players to sustain in the competition. The other strategies incorporated are computational advancements in software, mergers & acquisitions, and agreements for drug development.

For instance, In January 2015, Chemical Computing Group released an updated version of its protein structure database, PSILO. The enhanced features included a redesigned web interface and easy access to a vast repository of protein structures. Also, in May 2014, Dassault Systèmes announced the launch of BIOVIA, which is focused on enabling biological, chemical, materials designing, and molecular simulations as well as open collaborative research and quality management.

Report Scope

Attribute

Details

Base year for estimation

2015

Actual estimates/Historical data

2014 - 2015

Forecast period

2016 - 2025

Market representation

Revenue in USD Million & CAGR from 2016 to 2025

Regional scope

North America, Europe, Asia-Pacific, Latin America & MEA

Country scope

U.S., Canada, UK, Germany, Japan, China, Brazil, Mexico, South Africa

Report coverage             

Revenue forecast, company share, competitive landscape, growth factors and trends

15% free customization scope (equivalent to 5 analyst working days)

If you need specific market information, which is not currently within the scope of the report, we will provide it to you as a part of customization


Segments Covered in the Report

This report forecasts revenue growth and provides an analysis of the industry trends in each of the sub-segments from 2014 to 2025. For the purpose of this study, Grand View Research has segmented the structural biology & molecular modeling techniques market on the basis of tools, application, and region:

  • Tools Outlook (Revenue, USD Million, 2014 - 2025)

    • SaaS & standalone modeling

    • Homology modeling

    • Threading

    • Molecular dynamics

    • Ab Initio

    • Hybrid

    • Others

    • Visualization & analysis

    • Databases

    • Others

  • Application Outlook (Revenue, USD Million, 2014 - 2025)

    • Drug development

    • Drug discovery

    • Others

  • Regional Outlook (Revenue, USD Million, 2014 - 2025)

    • North America

      • U.S

      • Canada

    • Europe

      • Germany

      • UK

    • Asia Pacific

      • Japan

      • China

      • India

    • Latin America

      • Brazil

      • Mexico

    • The Middle East and Africa

      • South Africa

Key questions answered by the report
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