The global ankylosing spondylitis market size is expected to reach USD 11.08 billion by 2030, registering a CAGR of 6.4% from 2025 to 2033, according to a new report by Grand View Research, Inc. Presence of a strong product pipeline is likely to accelerate market growth. For instance, the positive phase-2b results of UCB S.A. pipeline product, Bimekizumab, makes it a potential drug candidate to be launched in the market over the forecast period.
Pharmaceutical companies are aiming at label expansion and patent extension for maintaining their share in the market. In October 2017, Johnson & Johnson Services received approval for Simponi Aria for AS treatment for the treatment active psoriatic arthritis (PsA) or active ankylosing spondylitis (AS). Such advancements in therapy area are expected to have a positive effect on the market growth.
Furthermore, presence of favorable reimbursement policies is anticipated to propel the growth. For instance, in Canada (Ontario) under the province’s public drug program, Novartis AG announced the reimbursement of Cosentyx for the treatment of ankylosing ankylosis. According to an article published by Novartis AG, approximately 20 to 40% of patients fail to achieve sufficient clinical improvement on anti-TNF drugs, which provides opportunities for companies to develop novel and effective drugs.
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The TNF Inhibitors segment dominated the market with the largest revenue share of 58.70% in 2024, driven by their strong efficacy in controlling inflammation and slowing ankylosing spondylitis progression.
The hospital pharmacy segment dominated the market with the largest revenue share of 47.80% in 2024, which can be attributed to the high administration of biologics and infusion-based therapies in hospital settings.
The retail pharmacy segment is projected to grow at the fastest CAGR of 7.9% over the forecast period, driven by increasing patient preference for convenient access to oral and self-injectable therapies.
North America held the largest share of the ankylosing spondylitis market in 2024, accounting for 57.32% of global revenue, due to the widespread availability of advanced biologics and biosimilars.
Grand View Research has segmented the global ankylosing spondylitis market report based on drug class, distribution channel, and region:
Ankylosing Spondylitis Drug Class Outlook (Revenue, USD Million, 2021 - 2033)
Non-Steroidal Anti-Inflammatory Drug (NSAID)
TNF Inhibitors
Humira
Simponi
Remicade
Enbrel
Cimzia
Other TNF Inhibitors
Other Drug Classes
Ankylosing Spondylitis Distribution Channel Outlook (Revenue, USD Million, 2021 - 2033)
Hospital Pharmacy
Retail Pharmacy
Others
Ankylosing Spondylitis Regional Outlook (Revenue, USD Million, 2021 - 2033)
North America
U.S.
Canada
Mexico
Europe
UK
Germany
France
Italy
Spain
Denmark
Sweden
Norway
Asia Pacific
Japan
China
India
Australia
South Korea
Thailand
Latin America
Brazil
Argentina
Middle East & Africa
South Africa
Saudi Arabia
UAE
Kuwait
List of Key Players in the Ankylosing Spondylitis Market
AbbiVie, Inc.
Amgen, Inc.
Pfizer, Inc.
Johnson & Johnson, Inc.
Novartis AG
UCB, Inc.
Eli Lilly and Company
Merck & Co., Inc.
Zydus Lifescience Ltd.
Izana Bioscience
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