Anticoagulants Market Size To Reach $55.72 Billion By 2033

Anticoagulants Market Growth & Trends

The global anticoagulants market size is estimated to reach USD 55.72 billion by 2033, registering to grow at a CAGR of 5.26% from 2026 to 2033, according to a new report by Grand View Research, Inc. The market is primarily driven by the increasing prevalence of cardiovascular diseases (CVDs) and growing aging population. According to WHO, in 2019, CVDs caused majority of deaths worldwide, accounting for 17.9 million fatalities, which is 32% of global deaths. Among these deaths, 85% were attributed to heart attack and stroke. Moreover, of the 17 million premature deaths caused by noncommunicable diseases, 38% were due to CVDs in the same year.

Moreover, sedentary lifestyles significantly contribute to the global rise of blood clots owing to physical inactivity, fueling the demand for anticoagulants. Physical inactivity has been linked to an increased risk of venous thromboembolism (VTE), a condition that encompasses pulmonary embolism (PE) and deep vein thrombosis (DVT). The condition arises when a blood clot occurs in a deep vein in the legs, while PE occurs when a blood clot travels from a deep vein to the lungs. As per the National Library of Medicine, VTE, which includes DVT and PE, impacts around 900,000 individuals in the U.S. annually. This led to several hundred thousand hospitalizations and approximately 300,000 deaths. The increasing prevalence of VTE and the growing demand for effective treatment options is expected to boost the market.

Furthermore, technological advancements are playing a significant role in boosting the anticoagulants market by driving innovation, improving the efficacy and safety of anticoagulant treatments, and enhancing patient monitoring and outcomes. Advancements in drug discovery and development have led to the creation of new anticoagulants with improved properties, such as longer half-lives, fewer interactions with other medications, and reduced bleeding risks. These novel anticoagulants offer patients more treatment options and better outcomes. According to NIH, gene therapy is a new approach for treatment of blood clots that involves the use of genes to correct the underlying genetic defect that causes clotting. This approach is still in its early stage of development but has potential to be an effective treatment for blood clots. For instance, in November 2022, the FDA approved Hemgenix, a gene therapy to treat adults with hemophilia B who are using Factor IX prophylaxis and have a history of repeated, serious bleeding episodes. It is a one-time gene therapy that delivers a gene for clotting factor IX to the liver.

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Anticoagulants Market Report Highlights

• Based on the drug category, the Novel Oral Anticoagulants (NOACs) segment dominated the global anticoagulants industry with a revenue share of 57.11% in 2025. Heparin segment is projected to experience significant growth over the forecast period.

• Oral anticoagulants held the largest revenue share of the global anticoagulants industry in 2025. Based on route of administration, the injectable anticoagulants segment is anticipated to experience growth from 2026 to 2033.

• The Atrial Fibrillation/Myocardial Infarction (Heart Attack) segment dominated the global anticoagulants industry in 2025. Deep Vein Thrombosis (DVT) is anticipated to experience significant growth over the forecast period.

• North America dominated the global anticoagulants industry with revenue share of 50.98% in 2025. Asia Pacific anticoagulants market is anticipated to grow at the fastest CAGR of 6.6% during the forecast period.

Anticoagulants Market Segmentation

Grand View Research has segmented the global anticoagulants market based on function, application, and region:

Anticoagulants Drug Category Outlook (Revenue, USD Million, 2021 - 2033)

• Novel Oral Anticoagulants (NOACs)

  • Eliquis

  • Xarelto

  • Savaysa & lixiana

  • Pradaxa

• Vitamin K Antagonist

• Direct Thrombin Inhibitors

• Heparin

  • Type

    • Low Molecular Weight Heparin

    • Ultra-low Molecular Weight Heparin

    • Unfractionated Heparin

  • Source

    • Porcine

    • Bovine

    • Others

• Others

Anticoagulants Route of Administration Outlook (Revenue, USD Million, 2021 - 2033)

• Oral Anticoagulants

• Injectable Anticoagulants

Anticoagulants Application Outlook (Revenue, USD Million, 2021 - 2033)

• Atrial Fibrillation/Myocardial Infarction (Heart Attack)

• Deep Vein Thrombosis (DVT)

• Pulmonary Embolism

• Other Applications

Anticoagulants Regional Outlook (Revenue, USD Billion, 2021 - 2033)

• North America

  • U.S.

  • Canada

  • Mexico

• Europe

  • UK

  • Germany

  • France

  • Italy

  • Spain

• Asia Pacific

  • China

  • Japan

  • India

  • Australia

  • South Korea

• Latin America

  • Brazil

  • Argentina

• Middle East & Africa

  • South Africa

  • Saudi Arabia

  • UAE

  • Kuwait

List of Key Players in Anticoagulants Market

• Aspen Holdings

• Pfizer Inc.

• Bristol-Myers Squibb Company

• GSK plc

• Sanofi

• Bayer AG

• Boehringer Ingelheim International GmbH

• DAIICHI SANKYO COMPANY, LIMITED

• Johnson & Johnson Services, Inc.

• Eisai Co., Ltd.