Home
»
Press Room
»
DNA Methylation Market Size To Reach $5.52Bn By 2033

DNA Methylation Market Size To Reach $5.52 Billion By 2033

October 2025 | Report Format: Electronic (PDF)

DNA Methylation Market Growth & Trends

The global DNA methylation market size is expected to reach USD 5.52 billion by 2033, registering a CAGR of 14.73% from 2025 to 2033, according to a new report by Grand View Research, Inc. The increased adoption of DNA methylation in the agrigenomics field remains a promising driver of this growth.

In January 2020, a research journal published in Springer stated that DNA methylation and expression analysis shows peanut foliar disease resistance genes have epialleles. DNA methylation analysis continues to open new doors of opportunities for researchers, and pharmaceutical companies. Increased research and developments in this field would further drive the DNA methylation industry in the coming years.

Furthermore, the growing prevalence of esophageal adenocarcinoma has contributed to the overall growth. According to the data published by the American Cancer Society (ACS), in 2022, an estimated 20,640 esophageal cancer cases were undiagnosed in the U.S. The chronic disease. resulted in 16,410 deaths.

Growing esophageal cancer cases in the U.S. highlight the urgent need for early intervention measures that can help improve the low survival rates for patients. In October 2022, a research article published by Fred Hutchinson Cancer Center stated that methylated DNA biomarkers could be used for the detection of esophageal adenocarcinoma and high-grade dysplasia.

The significant increase in the adoption of epigenetics-based treatment strategies, coupled with the broad nucleic acid-based diagnostic tests & kits commercialization is projected to drive the growth of the market. In May 2022, an article published in PubMed stated that theepigenetics-based treatment strategies are to be used for studying Alzheimer’s disease. However, a lack of expertise to perform DNA methylation experiments could restrict the growth. DNA methylation holds significant potential in various biotechnology applications, while the relatively low number of skilled professionals remains an obstacle to growth.

Key players operating in the market are taking several initiatives such as new product developments, entering into a strategic alliance, and regional expansion among others. For instance, in May 2022, Oxford Nanopore announced integrating Remora, a technique that offers accurate and real-time epigenetic insights with nanopore sequencing software. This would further offer simple access to accurate whole genome methylation detection. Similarly, in June 2020, Base Genomics announced of advancing and developing its DNA methylation technology. the aim is to sequence a large amount of epigenetic data from a blood test which could revolutionize the preventative medicine arena.

key Request a free sample copy or view report summary: DNA Methylation Market Report

DNA Methylation Market Report Highlights

By technique, the sequencing-based techniques segment dominated the DNA methylation market 2024, capturing a 44.14% share. The PCR-based techniques segment in the DNA methylation market is expected to grow significantly during the forecast period.
By product & service, reagents & kits segment accounted for the largest market revenue share of 60.19% in 2024. The services segment is expected to grow fastest during the forecast period.
By application, the oncology segment accounted for the largest market revenue share of 66.35% in 2024 and is also expected to register the fastest CAGR during the forecast period.
By end-use, the academic and research institutes segment will take the largest market revenue share of 40.47% in 2024. The hospitals & clinical laboratories segment is expected to register the fastest CAGR during the forecast period.
North America dominated the DNA methylation industry in 2024, accounting for a significant share of 41.29%. The DNA methylation industry in the U.S. is expected to grow significantly over the forecast period.
Asia Pacific is expected to grow fastest, with a CAGR of 15.72% during the forecast period, supported by various government initiatives.