Microbial Fermentation Technology Market Worth $49.39 Billion By 2030

March 2023 | Report Format: Electronic (PDF)

Microbial Fermentation Technology Market Growth & Trends

The global microbial fermentation technology market size is expected to reach USD 49.39 billion by 2030, registering a CAGR of 5.8% according to a new report by Grand View Research, Inc. Since fermentation is observed to be of utmost importance in the manufacturing of biopharmaceuticals, there is also a growing demand for microbial fermentation technology in biopharmaceutical manufacturing. This has led to increasing collaborations and developments in this market space.

For instance, in September 2021, BIOVECTRA and ABEC collaboratively announced that the latter company would provide CSR single-use microbial fermentation solutions to expand BIOVECTRA’s manufacturing capabilities. The newly installed solutions are expected to provide a faster turnaround time with high-growth microbial fermentation on large scale. Moreover, in September 2022, Cargill and Genomatica along with Cyclone Engineers are working on a project to scale up the bioreactor fermentation processing. This project is a part of the National Biotechnology and Biomanufacturing Initiative with a grant of USD 2.5 million.

Furthermore, technological advances in microbial fermentation platforms are also expected to supplement the market growth. For instance, several metabolic engineering approaches have been developed by researchers to enhance the performance of microbial cell factories used for the production of complex biologics or small molecules. Such continuous developments in this market space are likely to increase the adoption of this technology in biomanufacturing.

Additionally, various medications and vaccines, such as hormones, antibody fragments, and pneumococcal vaccines, are bio-manufactured using microbial fermentation techniques. Bacterial cells are often resistant to shear damage, enabling the use of high-shear radial impeller systems and high agitation rates. This gives the fermentors a high mass transfer potential, allowing them to accommodate fast metabolizing, high-cell density microbial cell cultivations and increasing the quantity of product that the bioprocesses can produce. Thus, with the increasing adoption of SUB fermentors for bacterial fermentation, the market is likely to witness significant growth in the coming years.

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Microbial Fermentation Technology Market Report Highlights

  • Based on application, the antibiotics segment captured the highest market revenue share in 2021. Increasing research activities due to the rise of antibiotic-resistant microbes have positively impacted market growth

  • Owing to the faster and more stable growth pattern of microorganisms, the use of fermentation in small molecule synthesis is expected to witness lucrative growth throughout the forecast period

  • By end-users, CMOs and CDMOs accounted for a significant share in 2021. The capacity expansion by several CMOs and the growing trend of outsourcing is expected to propel the segment revenue generation

  • Asia Pacific dominated the market in 2021 owing to the high number of operating CMOs and the growing biopharmaceutical industry in countries such as India, Japan, and China

  • Furthermore, the demand for biologics and biopharmaceuticals is increasing in Japan. As a result, Japanese firms are undertaking various strategic initiatives to enhance their domestic biomanufacturing operations
  • North America is anticipated to witness the fastest growth throughout the forecast period owing to the presence of a well-established biopharmaceutical industry coupled with a high number of fermentation solution providers

  • Continuous efforts by key players to improve their product offerings are also contributing to North America’s regional market growth

Microbial Fermentation Technology Market Segmentation

Grand View Research has segmented the global microbial fermentation technology market report based on application, end-user, and region:

Microbial Fermentation Technology Application Outlook (Revenue, USD Million, 2018 - 2030)

  • Antibiotics

  • Probiotics Supplements

  • Monoclonal Antibodies

  • Recombinant Proteins

  • Biosimilars

  • Vaccines

  • Enzymes

  • Small Molecules

  • Others

Microbial Fermentation Technology End-user Outlook (Revenue, USD Million, 2018 - 2030)

  • Bio-Pharmaceutical Companies

  • Contract Research Organizations (CROs)

  • CMOs & CDMOs

  • Academic & Research Institutes

Microbial Fermentation Technology Regional Outlook (Revenue, USD Million, 2018 - 2030)

  • North America

    • U.S.

    • Canada

  • Europe

    • UK

    • Germany

    • France

    • Italy

    • Spain

    • Denmark

    • Sweden

    • Norway

  • Asia Pacific

    • Japan

    • China

    • India

    • South Korea

    • Australia

    • Thailand

  • Latin America

    • Brazil

    • Mexico

    • Argentina

  • Middle East & Africa

    • South Africa

    • Saudi Arabia

    • UAE

    • Kuwait

List of Key Players in Microbial Fermentation Technology Market

  • Biocon Ltd.

  • BioVectra Inc.

  • Danone UK

  • F. Hoffmann-La Roche AG

  • Koninklijke DSM NV

  • Lonza

  • Novozymes A/S

  • TerraVia Holdings, Inc.


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