The global osteoarthritis therapeutics market size is estimated to reach USD 13.57 billion by 2030 and is projected to grow at a CAGR of 6.82% from 2024 to 2030, according to a new report by Grand View Research, Inc. The osteoarthritis therapeutics market is on the rise, driven by an increase in OA cases, especially among the aging population. In the U.S. alone, there are over 32.5 million OA patients, highlighting the demand for effective treatments. Ongoing research and development efforts are focused on creating new therapies, with a particular emphasis on understanding the disease and developing solutions to address its challenges.
Managing OA proves difficult owing to its dense tissue structure, but the introduction of novel drugs such as intra-articular drug administration has accelerated the development of targeted drug delivery. Researchers are actively exploring disease-modifying drugs and bioadaptive carriers to enhance the development of innovative osteoarthritis treatments. Market players are taking initiatives to contribute to market expansion, as seen with OrthoTrophix, Inc. presenting clinical data and a registration plan for TPX-100 for knee osteoarthritis at BIO 2022.
In addition, significant efforts are being made by key pharmaceutical companies and research institutes in realm of research and development, especially for disease-modifying osteoarthritis drugs. For instance, BioSenic's Phase 3 data presentation at the 2024 OARSI World Congress showcased the efficacy of JTA-004 in treating severe inflammatory knee osteoarthritis. The post hoc analysis concluded that JTA-004 is both safe and effective, offering targeted pain management for this specific subtype of condition. These advancements in targeted drug delivery and disease-modifying drugs, as demonstrated by presentations and positive trial results, are contributing to the expansion of the market for novel osteoarthritis treatments.
Moreover, the market for OA is experiencing significant growth owing to the introduction of personalized medications such as Bisphosphonates (anti-resorptive drugs) and Synvisc-ONE injection. In addition, pharmaceutical companies and research institutions are actively engaged in developing personalized treatments and cell-based therapies for OA. In December 2023, researchers at Columbia University made a breakthrough discovery of stem cells in adult mice capable of maintaining healthy cartilage in joints, with their decline contributing to OA development due to aging and injury.
Investing in this sector offers companies the opportunity to capitalize on evolving demands, thus gaining a competitive advantage. By leading innovative medication development, companies establish themselves as frontrunners, solidifying their position in the market. The advent of personalized OA medications and advancements in cell-based therapies are key drivers of market expansion, empowering companies to emerge as leaders in the field.
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Based on drug type, the viscosupplementation agents segment led the market with the largest revenue share of 36.63% in 2023, osteoarthritis therapeutics market due to their adoption and efficacy in managing OA symptoms
Based on anatomy, the knee osteoarthritis segment held a market with the largest revenue share of 41.96% in 2023. Knee osteoarthritis is one of the most common forms of chronic articular disease and osteoarthritis worldwide and is characterized by high disability & morbidity rates
Based on route of administration, the parenteral route segment held the market with the largest revenue share of 39.94% in 2023 and is expected to grow at a CAGR of 7.50% over the forecast period, due to its efficacy for certain therapies, better pharmacokinetics and pharmacodynamics, and ease of administration
Based on end-use, the hospital pharmacies segment held the market with the largest revenue share of 47.64% in 2023, owing to high hospitalization associated with OA
Grand View Research has segmented the global osteoarthritis therapeutics market based on drug type, anatomy, route of administration, sales channel, end-use and region:
Osteoarthritis Therapeutics Drug Type Outlook (Revenue, USD Million, 2018 - 2030)
Viscosupplementation Agents
Nonsteroidal Anti-inflammatory Drugs
Naproxen
Aspirin
Diclofenac
Ibuprofen
Celecoxib
Meloxicam
Piroxicam
Ketoprofen
Other NSAIDs
Analgesics
Duloxetine
Acetaminophen
Corticosteroids
Others
Osteoarthritis Therapeutics Anatomy Outlook (Revenue, USD Million, 2018 - 2030)
Knee Osteoarthritis
Hip Osteoarthritis
Hand Osteoarthritis
Others
Osteoarthritis Therapeutics Route of Administration Outlook (Revenue, USD Million, 2018 - 2030)
Parenteral Route
Hyaluronic Acid Injections
Corticosteroid Injections
Platelet-rich Plasma (PRP) Injections
Placental Tissue Matrix (PTM) Injections
Acetylsalicylic Acid (ASA) Injections
Others
Topical Route
Oral Route
Osteoarthritis Therapeutics Sales Channel Outlook (Revenue, USD Million, 2018 - 2030)
Prescription Drugs
Over-the-Counter Drugs
Osteoarthritis Therapeutics End-use Outlook (Revenue, USD Million, 2018 - 2030)
Hospital Pharmacies
Retail Pharmacies
Others
Osteoarthritis Therapeutics Regional Outlook (Revenue, USD Million, 2018 - 2030)
North America
U.S.
Canada
Europe
Germany
UK
Spain
France
Italy
Denmark
Sweden
Norway
Asia Pacific
Japan
China
India
South Korea
Australia
Thailand
Latin America
Brazil
Mexico
Argentina
MEA
South Africa
Saudi Arabia
UAE
Kuwait
List of Key Players in the Osteoarthritis Therapeutics Market
Sanofi SA
GlaxoSmithKline plc
Pfizer Inc
Bayer AG
Zimmer Biomet
Novartis AG
Anika Therapeutics
Assertio Therapeutics, INC.
Bioventus
Ferring Pharmaceuticals Inc.
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