Protein Chip Market Size To Reach $4.14 Billion By 2033

October 2025 | Report Format: Electronic (PDF)

Protein Chip Market Growth & Trends

The global protein chip market size is expected to reach USD 4.14 billion by 2033, registering a CAGR of 7.74% from 2025 to 2033, according to a new report by Grand View Research, Inc. This is attributed to the continuous advancements in proteomics research, increasing drug discovery and developments, and ongoing technological advancements are anticipated to increase the demand for protein chips over the forecast period.

The COVID-19 pandemic has had a positive impact on the global market. The COVID-19 outbreak has brought to the forefront the significance of cutting-edge technologies such as protein chips in tackling worldwide health issues. This has spurred innovation, amplified investments, and broadened the use cases of protein chips in disease investigation, diagnostics, and tailored healthcare.

The growing prevalence of chronic diseases such as cancer, cardiovascular diseases, and neurological disorders fuels the demand for advanced tools for disease diagnosis and treatment. Protein chips enable the identification of disease-specific protein biomarkers, aiding in early detection and personalized treatment strategies. For instance, in October 2023, Sengenics Corporation LLC announced the launch of i-Ome Discovery, a precise protein microarray platform for detecting disease-related autoantibodies. It aids academic and clinical research teams in understanding protein-immune system interactions in diseases. Utilizing Sengenics' patented KREX technology, it offers accurate detection of over 1,800 autoantigens relevant to cancer, autoimmune, and neurodegenerative disorders. Thus, anticipated to propel the demand for market growth over the forecast period.

However, protein chip technologies often require expensive equipment, reagents, and specialized expertise, which can pose a barrier to entry for some researchers and laboratories. The high cost of protein chip assays may limit their use in resource-constrained settings or for large-scale studies. Moreover, protein chip technologies involve complex procedures for protein immobilization, assay development, and data analysis. Thus, standardization and reproducibility across different platforms and laboratories is challenging, thus limiting the widespread adoption of protein chips. Thereby anticipated to hamper the market growth.

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Protein Chip Market Report Highlights

The analytical microarrays led the market with the largest revenue share of 54.81% in 2024 and is anticipated to grow at the fastest CAGR over the forecast period.
The antibody characterization segment led the market with the largest revenue share of 56.88% in 2024. The clinical diagnostics segment is expected to grow at the fastest CAGR over the forecast period.
Based on end-use, the academic & research institutes segment led the market with the largest revenue share of 51.71% in 2024. The diagnostic laboratories segment is expected to grow at the fastest CAGR during the forecast period.
North America dominated the protein chip market with a share of 40.15% in 2024. The protein chip market in the Asia Pacific is anticipated to grow at the fastest CAGR of 10.63% over the forecast period.