The global radiation oncology market size is expected to reach USD 33.09 billion by 2033, registering a CAGR of 11.42% from 2026 to 2033, according to a new report by Grand View Research, Inc. The growth of the market is attributed to the global rise in cancer burden, the growing geriatric population, and supportive reimbursement programs undertaken by the government and private organizations. Furthermore, the increasing technological innovation and advancement in radiotherapy offer lucrative opportunities for market growth.
The world is witnessing an increasing prevalence of cancer cases which is the key factor driving the radiation oncology market growth. For instance, according to Globocan, in 2020, more than 20.0 million people were diagnosed with cancer, and 10.0 million died of cancer. Moreover, the aging population is at high risk of cancer due to a weak immune system and comorbid conditions; thereby, the rising geriatric population further fuels market growth. For instance, in 2020, according to WHO estimates, the global geriatric population was approximately 1.0 billion and is expected to reach 2.1 billion by 2050.
Extensive research activities for the development of novel radiotherapy techniques and multidisciplinary therapeutic approaches are expected to lead to an increased survival rate and a more favorable prognosis of cancer. For instance, in December 2022, Elekta Unity demonstrated MR-Linac use for pancreatic tumors, where the first-ever patient was treated with new advanced radiotherapy motion management.
Similarly, in June 2020, Isoray signed a research agreement with the University of Cincinnati Physicians Company to study neck and head cancer treatment. The companies will evaluate the efficacy of Keytruda along with Cesium-131 post-surgical resection. Using such medical isotopes for cancer treatment may boost the research in developing a new target-specific radiation therapy system by understanding disease complexity & patients' need, thereby widening the opportunity in the market.
Furthermore, supportive reimbursement and regulatory policies for radiation therapy are also expected to drive the radiation oncology market growth. For instance, in July 2021, the Centers for Medicare and Medicaid Services (CMS) developed a new Radiation Oncology Payment Model (RO-APM) for the diagnosis of cancer and radiotherapy services. It enhances the quality of care of the patients and reduces the annual Medicare expenditure.
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By treatment, the external beam radiation therapy (EBRT) treatment segment held the largest share of 73.22% in 2025. The systemic targeted radiation therapy segment is expected to grow at a CAGR of 15.20% during the forecast period.
By technology, the intensity-modulated radiotherapy (IMRT) segment held the largest revenue share of 20.38% in 2025. The upright beam delivery technology segment is expected to grow at the fastest CAGR over the forecast period.
By target customers, the academic & research cancer centers segment held the largest revenue share of 32.17% in 2025. Nuclear medicine and theranostics centers are emerging as a high-growth targeted customer segment within the market, driven by the rapid evolution of precision oncology and radioligand therapy.
By application, the external beam radiation therapy (EBRT) segment held the largest revenue share in 2025. The radioligand therapy (RLT) application segment is experiencing notable growth within the oncology landscape, supported by increasing investment and expanding research in targeted radiopharmaceuticals.
North America radiation oncology industry dominated the global market and accounted for the largest revenue share of 46.21% in 2025. U.S. led the North America market and held the largest revenue share in 2025.
Grand View Research has segmented global radiation oncology market report based on treatment, technology, application, target customer, and region:
Radiation Oncology Treatment Outlook (Revenue, USD Million, 2021 - 2033)
External Beam Radiation Therapy (EBRT)
Linear Accelerators (LINAC)
Stereotactic Radiosurgery (SRS) Systems
Tomotherapy Systems
Particle Beam Therapy
Proton Therapy
Heavy-Ion Therapy
Internal Beam Radiation Therapy
Brachytherapy
Low-Dose Rate (LDR) Brachytherapy
Seeds
High-Dose Rate (HDR) Brachytherapy
Afterloaders
Applicators
Electronic Brachytherapy
Systemic Targeted Radiation Therapy
Radioligand Therapy (RLT)
Beta-Emitting Radioligand Therapies
Alpha-Emitting Radioligand Therapies
Radiation Oncology Technology Outlook (Revenue, USD Million, 2021 - 2033)
Image-Guided Radiotherapy (IGRT)
Motion Tracking / Real-Time Tumor Tracking
Other
Intensity-Modulated Radiotherapy (IMRT)
Volumetric Modulated Arc Therapy (VMAT)
3D Conformal Radiation Therapy (3D-CRT)
Stereotactic Radiotherapy (SRS / SBRT)
Proton Beam Delivery Technology
Heavy-Ion Delivery Technology
Adaptive Radiotherapy
Upright Beam Delivery Technology
Radiation Oncology Application Outlook (Revenue, USD Million, 2021 - 2033)
External Beam Radiation Therapy (EBRT)
Prostate Cancer
Breast Cancer
Lung Cancer
Head & Neck Cancer
Colorectal Cancer
Central Nervous System (CNS) Tumors
Others (e.g., Pediatric Cancers)
Internal Beam Radiation Therapy
Prostate Cancer
Gynecological Cancer
Cervical Cancer
Breast Cancer
Others (e.g., Penile Cancer)
Radioligand Therapy Applications
Prostate Cancer
Neuroendocrine Tumors
Thyroid Cancer
Others (e.g., Hematologic Malignancies)
Radiation Oncology Target Customer Outlook (Revenue, USD Million, 2021 - 2033)
Academic & Research Cancer Centers
Government & Public Tertiary Hospitals
Private Oncology Chains
Specialty Proton / Particle Therapy Centers
Nuclear Medicine & Theranostics Centers
Radiation Oncology Regional Outlook (Revenue, USD Million, 2021 - 2033)
North America
U.S.
Canada
Mexico
Europe
Germany
UK
France
Italy
Spain
Denmark
Sweden
Norway
Asia Pacific
Japan
China
India
Australia
South Korea
Thailand
Latin America
Brazil
Argentina
Middle East and Africa (MEA)
South Africa
Saudi Arabia
UAE
Kuwait
List of Key Players of Radiation Oncology Market
Varian Medical Systems, Inc. (Siemens Healthineers).
Elekta AB
Accuray Incorporated
IBA (Ion Beam Applications)
BD (Becton, Dickinson and Company)
Curium
Panacea Medical Technologies
Mevion Medical Systems
Canon Medical Systems Corporation
Sumitomo Heavy Industries, Ltd.
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