Surgical Sealants & Adhesives Market To Reach $5.0 Billion By 2033

Surgical Sealants And Adhesives Market Growth & Trends

The global surgical sealants and adhesives market size is estimated to reach USD 5.0 billion by 2033, registering a CAGR of 8.0% from 2026 to 2033, according to a new report by Grand View Research, Inc. Proper closure of injured tissues post-operation is a major step to restore tissue’s structure and function. Postoperative leakages occur in 3% to 15% of cases and are considered serious complications. They are responsible for one-third of postoperative deaths in patients. Surgical sealants and adhesives are designed to improve patient outcomes by reducing the prospect of postsurgical complications, such as leakages, thus resulting in improved patient outcomes through the prevention of leakage and a decrease in length of stay and mortality rates.

The rapid advancements in sealants and adhesives are major impact rendering drivers, and their usage in modern surgery to reduce anastomotic leakage has risen significantly. Surgical adhesive is expected to replace traditional surgical sealing agents such as sutures, wires, and staples. These are time taking, can result in further tissue trauma, and are hard to use in some surgical locations. Surgical sealants overcome these issues and create immediate and proper sealing, compared to sutures and staples. The factors contributing to the growth of the market are the rising demand for surgical services worldwide and increasing concerns to reduce postoperative wound infections. Surgical procedures are increasing worldwide, with the WHO estimations projecting surgeries to account for approximately 235 million per year globally.

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Surgical Sealants And Adhesives Market Report Highlights

• Based on type, the natural/biological sealants and adhesives segment led the market with the largest revenue share of 65.0% in 2025. The dominance of this segment can be due to the broad applications of various natural or biological sealants in medical practice.

• Based on indication, the tissue sealing segment led the market with the largest revenue share in 2025. This is due to the rise in surgical interventions and increasing product launches from major players.

• Based on application, the general surgery segment led the market with the largest revenue share of 22.9% in 2025, due to the high volume of surgeries conducted annually.

• North America dominated the surgical sealants and adhesives market with the revenue share of 49.7% in 2025, due to the high prevalence of chronic diseases such as cardiovascular disorders and cancer, which drive the demand for advanced medical solutions, including surgical adhesives and sealants, to manage surgical interventions effectively.

Surgical Sealants And Adhesives Market Segmentation

Grand View Research has segmented the global surgical sealants and adhesives market based on type, indication, application, and region:

Surgical Sealants And Adhesives Type Outlook (Revenue, USD Million, 2021 - 2033)

• Natural or Biological Adhesives and Sealants

  • Fibrin Sealants

  • Collagen Based Adhesives

  • Gelatin Based Adhesives

• Synthetic and Semi Synthetic Adhesives and Sealants

  • Cyanoacrylates

  • Polymeric Hydrogels

  • Urethane Based Adhesives

Surgical Sealants And Adhesives Indication Outlook (Revenue, USD Million, 2021 - 2033)

• Tissue Sealing

• Tissue Engineering

• Hemostasis

Surgical Sealants And Adhesives Application Outlook (Revenue, USD Million, 2021 - 2033)

• Central Nervous System

• Cardiovascular

• General surgery

• Orthopedic

• Cosmetic

• Pulmonary

• Urology

• Ophthalmology

• Others

Surgical Sealants And Adhesives Regional Outlook (Revenue, USD Million, 2021 - 2033)

• North America

  • U.S.

  • Canada

  • Mexico

• Europe

  • Germany

  • UK

  • France

  • Italy

  • Spain

  • Norway

  • Sweden

  • Denmark

• Asia Pacific

  • China

  • Japan

  • India

  • Thailand

  • South Korea

  • Australia

• Latin America

  • Brazil

  • Argentina

• MEA

  • South Africa

  • Saudi Arabia

  • UAE

  • Kuwait

List of Key Players in the Surgical Sealants And Adhesives Market 

• Johnson & Johnson (Ethicon)

• Artivion, Inc (CryoLife, Inc.)

• C.R. Bard, Inc. (BD)

• Medtronic

• B. Braun SE

• Mallinckrodt

• Cardinal Health

• Baxter

• Integra LifeSciences Corporation

• Stryker