GVR Report cover Surgical Sealants And Adhesives Market Size, Share & Trends Report

Surgical Sealants And Adhesives Market Size, Share & Trends Analysis Report By Type (Natural or Biological Adhesives & Sealants, Synthetic & Semi Synthetic Adhesives), By Application, By Region, And Segment Forecasts, 2023 - 2030

  • Report ID: GVR-1-68038-411-6
  • Number of Pages: 105
  • Format: Electronic (PDF)
  • Historical Range: 2018 - 2021
  • Industry: Healthcare

Market Size & Trends

The global surgical sealants and adhesives market size was valued at USD 2.2 billion in 2022 and is expected to grow at a compound annual growth rate (CAGR) of 11.6% from 2023 to 2030. Sealants and adhesives have evolved to become useful accompaniments in modern surgical procedures. They are widely preferred because of their safety, efficacy, and usability in repairing injured tissues and supporting wounds obtained during surgery. The pandemic caused by COVID-19 across the globe resulted in nationwide lockdowns and exerted pressure on the healthcare settings. According to the list provided by the American College of Surgeons, all dental, medical, or surgical procedures that are nonessential and elective in nature were postponed, except for medical emergencies.

U.S. surgical sealants and adhesives market size and growth rate, 2023 - 2030

Factors contributing to the growth of this market are the rising demand for surgical services and increasing concerns about reducing surgical wounds. Globally, the number of surgeries being undertaken has increased significantly. According to the WHO estimations, approximately 235 million major surgical procedures are undertaken worldwide every year. Surgical procedures are normally accompanied by the risk of wound infection, excessive bleeding, or tissue damage. In addition, patients suffering from diabetes need to be extra cautious as the chances of complications during and post-surgery are significantly higher in their case.

As the volume of surgeries is increasing, extensive R&D activities focused on the widening applications of surgical sealants and adhesives are also rising. Traditional alternatives to surgical sealants are sutures and staples, which are expected to be replaced by surgical sealants and adhesives owing to their better wound closure capabilities with minimal blood loss. The sealants facilitate less painful operations and do not need removal. For instance, in March 2023, Scientists from Terasaki Institute for Biomedical Innovation (TIBI) have developed injectable biomaterial with considerably improved stretchability, toughness, and adhesive strength. Such advancements in the products are anticipated to fuel the market growth over the forecast period.

Product Insights

The natural/biological sealants and adhesives segment held the largest revenue share of over 62.0% in 2022. Natural or biological sealants and adhesives are further classified into fibrin, collagen-based, and gelatin-based. Fibrin sealants held the largest revenue share of over 38.0% in 2022 owing to their broad applications in medical practice. They find effective applications in thoracic, cardiovascular, orthopedic, neuro, and reconstructive surgeries. Furthermore, fibrin, among other sealants, is the only product to have received approval from the FDA, to be used under all three groups, namely hemostats, sealants, and adhesives.

The synthetic and semi-synthetic sealants and adhesives segment is classified into cyanoacrylates, polymeric hydrogels, and urethane-based adhesives. Cyanoacrylates are expected to register the fastest growth rate in the forecast period owing to their high-speed drying rate. Its strong mechanical strength and ease of adhesion are responsible for its increased adoption in surgical practices worldwide. However, cyanoacrylates are known to cause intense inflammatory responses, when exposed to non-cutaneous surfaces, restricting their use in internal surgeries. It can only be utilized in external injuries and surgeries, as a result of which its market growth is expected to be hindered.

Application Insights

The general surgery segment held the largest revenue share of over 26.0% in 2022. The central nervous system (CNS) segment held the second-largest revenue share in 2021 owing to the high prevalence of CNS disorders globally. Sealants are a top choice in CNS surgeries over traditional closure methods such as wires, sutures, and staples. Traditional sealant methods are difficult to use in CNS surgeries and as a result, the demand for surgical sealants and adhesives for CNS has risen exponentially.

Global surgical sealants and adhesives market share and size, 2022

By application, the market is segmented into central nervous system, cardiovascular, general surgery, orthopedic, cosmetic, pulmonary, urology, ophthalmology, and others. The cardiovascular segment held a considerable revenue share in 2022. A rising number of cardiovascular interventions and cardiovascular surgeries such as open-heart surgery, cardiac valve procedures, and heart transplant procedures is expected to contribute to the growth of the market in the forecast period.

Regional Insights

North America held the largest revenue share of over 38.08% in 2022 owing to the high-quality healthcare and modern medical technology in the region. Furthermore, the rising importance of surgical care in the public health policies in the U.S. is expected to positively contribute to the growth of the market. Another contributing factor is the local presence of many major market players, such as Baxter International, CryoLife, and Johnson & Johnson.

Surgical Sealants And Adhesives Market Trends, by Region, 2023 - 2030

Asia Pacific is expected to witness significant growth over the forecast period because of the ongoing transformation of healthcare delivery systems into advanced value-based healthcare practices that create a sustainable health system. This will help people avail cheaper and better facilities at low costs and promote the use of novel techniques in surgeries and other healthcare practices.

Key Companies & Market Share Insights

Market participants combine a blend of both large public companies and many specialized companies focused on only one segment or product, often termed as “Pure Play” companies. For instance, Cohera Medical, Inc.’s product portfolio only involves surgical sealants. However, new local players in the market are expected to emerge and increase competition.

Leading players are continuously implementing various strategies to attain a dominant market position. For instance, in May 2023, Sealonix, Inc. announced closing of USD 20.0 Million financing to produce sealant products for orthopedic as well as abdominopelvic procedures. Some prominent players in the global surgical sealants and adhesives market include:

  • Baxter International, Inc.

  • CryoLife, Inc.

  • C.R. Bard, Inc.

  • Medtronic PLC

  • B. Braun Melsungen AG

  • Cohera Medical, Inc.

  • Ethicon, Inc. [J&J]

  • Mallinckrodt plc

  • Cardinal Health

  • Integra LifeSciences Holdings Corporation

Surgical Sealants And Adhesives Market Report scope

Report Attribute


Market size value in 2023

USD 2.5 billion

Revenue forecast in 2030

USD 5.4 billion

Growth rate

CAGR of 11.6% from 2023 to 2030

Base year for estimation


Historical data

2018 - 2021

Forecast period

2023 - 2030

Report Updated

May 2023

Quantitative units

Revenue in USD million/billion & CAGR from 2023 to 2030

Report coverage

Revenue forecast, volume forecast, company ranking, competitive landscape, growth factors, and trends

Segment scope

Type, application, region

Regional scope

North America; Europe; Asia Pacific; Latin America; MEA

Country scope

U.S.; Canada; U.K.; Germany; France; Italy; Spain; Denmark; Norway; Sweden; India; Singapore; South Korea; China; Japan; India; Australia; Thailand; South Korea; Brazil; Mexico; Argentina; South Africa; Saudi Arabia; UAE; Kuwait

Key companies profiled

Baxter International, Inc.; CryoLife, Inc.; C.R. Bard, Inc.; Medtronic PLC; B. Braun Melsungen AG; Cohera Medical, Inc.; Ethicon, Inc. [J&J]; Mallinckrodt plc; Cardinal Health; Integra LifeSciences Holdings Corporation

Customization scope

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Global Surgical Sealants And Adhesives Market Report Segmentation

This report forecasts revenue growth at global, regional & country levels and provides an analysis on the latest trends and opportunities in each of the sub-segments from 2018 to 2030. For the purpose of this study, Grand View Research has segmented the global surgical sealants and adhesives market report on the basis of product, application and region:

Global Surgical Sealants And Adhesives Market Report Segmentation

  • Product Outlook (Revenue, USD Million; 2018 - 2030)

    • Natural/Biological Adhesives And Sealants 

      • Fibrin Sealants

      • Collagen Based Adhesives

      • Gelatin Based Adhesives

    • Synthetic & Semi Synthetic Adhesives And Sealants 

      • Cyanoacrylates

      • Polymeric Hydrogels

      • Urethane Based Adhesives

  • Application Outlook (Revenue, USD Million; 2018 - 2030)

    • Central Nervous System Surgery

    • Cardiovascular Surgery

    • General Surgery

    • Orthopedic Surgery

    • Cosmetic Surgery

    • Pulmonary Surgery

    • Urology Surgery

    • Ophthalmology Surgery

    • Others

  • Regional Outlook (Revenue, USD Million; 2018 - 2030)

    • North America

      • U.S.

      • Canada

    • Europe

      • UK

      • Germany

      • France

      • Italy

      • Spain

      • Denmark

      • Sweden

      • Norway

    • Asia Pacific

      • Japan

      • China

      • India

      • Australia

      • South Korea

      • Thailand

    • Latin America

      • Brazil

      • Mexico

      • Argentina

      • Colombia

    • Middle East and Africa (MEA)

      • South Africa

      • Saudi Arabia

      • UAE

      • Kuwait

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