The global surgical sealants and adhesives market size was valued at USD 2.2 billion in 2022 and is expected to grow at a compound annual growth rate (CAGR) of 11.6% from 2023 to 2030. Sealants and adhesives have evolved to become useful accompaniments in modern surgical procedures. They are widely preferred because of their safety, efficacy, and usability in repairing injured tissues and supporting wounds obtained during surgery. The pandemic caused by COVID-19 across the globe resulted in nationwide lockdowns and exerted pressure on the healthcare settings. According to the list provided by the American College of Surgeons, all dental, medical, or surgical procedures that are nonessential and elective in nature were postponed, except for medical emergencies.
Factors contributing to the growth of this market are the rising demand for surgical services and increasing concerns about reducing surgical wounds. Globally, the number of surgeries being undertaken has increased significantly. According to the WHO estimations, approximately 235 million major surgical procedures are undertaken worldwide every year. Surgical procedures are normally accompanied by the risk of wound infection, excessive bleeding, or tissue damage. In addition, patients suffering from diabetes need to be extra cautious as the chances of complications during and post-surgery are significantly higher in their case.
As the volume of surgeries is increasing, extensive R&D activities focused on the widening applications of surgical sealants and adhesives are also rising. Traditional alternatives to surgical sealants are sutures and staples, which are expected to be replaced by surgical sealants and adhesives owing to their better wound closure capabilities with minimal blood loss. The sealants facilitate less painful operations and do not need removal. For instance, in March 2023, Scientists from Terasaki Institute for Biomedical Innovation (TIBI) have developed injectable biomaterial with considerably improved stretchability, toughness, and adhesive strength. Such advancements in the products are anticipated to fuel the market growth over the forecast period.
The natural/biological sealants and adhesives segment held the largest revenue share of over 62.0% in 2022. Natural or biological sealants and adhesives are further classified into fibrin, collagen-based, and gelatin-based. Fibrin sealants held the largest revenue share of over 38.0% in 2022 owing to their broad applications in medical practice. They find effective applications in thoracic, cardiovascular, orthopedic, neuro, and reconstructive surgeries. Furthermore, fibrin, among other sealants, is the only product to have received approval from the FDA, to be used under all three groups, namely hemostats, sealants, and adhesives.
The synthetic and semi-synthetic sealants and adhesives segment is classified into cyanoacrylates, polymeric hydrogels, and urethane-based adhesives. Cyanoacrylates are expected to register the fastest growth rate in the forecast period owing to their high-speed drying rate. Its strong mechanical strength and ease of adhesion are responsible for its increased adoption in surgical practices worldwide. However, cyanoacrylates are known to cause intense inflammatory responses, when exposed to non-cutaneous surfaces, restricting their use in internal surgeries. It can only be utilized in external injuries and surgeries, as a result of which its market growth is expected to be hindered.
The general surgery segment held the largest revenue share of over 26.0% in 2022. The central nervous system (CNS) segment held the second-largest revenue share in 2021 owing to the high prevalence of CNS disorders globally. Sealants are a top choice in CNS surgeries over traditional closure methods such as wires, sutures, and staples. Traditional sealant methods are difficult to use in CNS surgeries and as a result, the demand for surgical sealants and adhesives for CNS has risen exponentially.
By application, the market is segmented into central nervous system, cardiovascular, general surgery, orthopedic, cosmetic, pulmonary, urology, ophthalmology, and others. The cardiovascular segment held a considerable revenue share in 2022. A rising number of cardiovascular interventions and cardiovascular surgeries such as open-heart surgery, cardiac valve procedures, and heart transplant procedures is expected to contribute to the growth of the market in the forecast period.
North America held the largest revenue share of over 38.08% in 2022 owing to the high-quality healthcare and modern medical technology in the region. Furthermore, the rising importance of surgical care in the public health policies in the U.S. is expected to positively contribute to the growth of the market. Another contributing factor is the local presence of many major market players, such as Baxter International, CryoLife, and Johnson & Johnson.
Asia Pacific is expected to witness significant growth over the forecast period because of the ongoing transformation of healthcare delivery systems into advanced value-based healthcare practices that create a sustainable health system. This will help people avail cheaper and better facilities at low costs and promote the use of novel techniques in surgeries and other healthcare practices.
Market participants combine a blend of both large public companies and many specialized companies focused on only one segment or product, often termed as “Pure Play” companies. For instance, Cohera Medical, Inc.’s product portfolio only involves surgical sealants. However, new local players in the market are expected to emerge and increase competition.
Leading players are continuously implementing various strategies to attain a dominant market position. For instance, in May 2023, Sealonix, Inc. announced closing of USD 20.0 Million financing to produce sealant products for orthopedic as well as abdominopelvic procedures. Some prominent players in the global surgical sealants and adhesives market include:
Baxter International, Inc.
C.R. Bard, Inc.
B. Braun Melsungen AG
Cohera Medical, Inc.
Ethicon, Inc. [J&J]
Integra LifeSciences Holdings Corporation
Market size value in 2023
USD 2.5 billion
Revenue forecast in 2030
USD 5.4 billion
CAGR of 11.6% from 2023 to 2030
Base year for estimation
2018 - 2021
2023 - 2030
Revenue in USD million/billion & CAGR from 2023 to 2030
Revenue forecast, volume forecast, company ranking, competitive landscape, growth factors, and trends
Type, application, region
North America; Europe; Asia Pacific; Latin America; MEA
U.S.; Canada; U.K.; Germany; France; Italy; Spain; Denmark; Norway; Sweden; India; Singapore; South Korea; China; Japan; India; Australia; Thailand; South Korea; Brazil; Mexico; Argentina; South Africa; Saudi Arabia; UAE; Kuwait
Key companies profiled
Baxter International, Inc.; CryoLife, Inc.; C.R. Bard, Inc.; Medtronic PLC; B. Braun Melsungen AG; Cohera Medical, Inc.; Ethicon, Inc. [J&J]; Mallinckrodt plc; Cardinal Health; Integra LifeSciences Holdings Corporation
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This report forecasts revenue growth at global, regional & country levels and provides an analysis on the latest trends and opportunities in each of the sub-segments from 2018 to 2030. For the purpose of this study, Grand View Research has segmented the global surgical sealants and adhesives market report on the basis of product, application and region:
Product Outlook (Revenue, USD Million; 2018 - 2030)
Natural/Biological Adhesives And Sealants
Collagen Based Adhesives
Gelatin Based Adhesives
Synthetic & Semi Synthetic Adhesives And Sealants
Urethane Based Adhesives
Application Outlook (Revenue, USD Million; 2018 - 2030)
Central Nervous System Surgery
Regional Outlook (Revenue, USD Million; 2018 - 2030)
Middle East and Africa (MEA)
b. The global surgical sealants and adhesives market size was estimated at USD 2.2 billion in 2022 and is expected to reach USD 2.5 billion in 2023.
b. The global surgical sealants and adhesives market is expected to grow at a compound annual growth rate of 11.6% from 2023 to 2030 to reach USD 5.4 billion by 2030.
b. The general surgery segment in application accounted for the largest market share in the year 2022 with a market share of more than 17.0%.
b. Some key players operating in the surgical sealants and adhesives market include Baxter International, Inc.; CryoLife, Inc.; C.R. Bard, Inc.; Medtronic PLC; B. Braun Melsungen AG; Cohera Medical, Inc.; Ethicon, Inc. [J&J]; Mallinckrodt plc; and Cardinal Health.
b. Key factors that are driving the surgical sealants and adhesives market growth include rising demand for surgical services and increasing concerns to reduce surgical wounds.
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