U.S. Longevity & General Wellness Supplements Market To Reach $10.13 Billion By 2033

U.S. Longevity & General Wellness Supplements Market Growth & Trends

The U.S. longevity & general wellness supplements market size is expected to reach USD 10.13 billion by 2033, registering a CAGR of 6.06% from 2026 to 2033, according to a new report by Grand View Research, Inc. The market is expanding rapidly, driven by the growing consumer focus on healthy aging and preventive healthcare to enhance quality of life and extend lifespan. Advancements in nutraceutical formulations, including vitamins, minerals, botanicals, and bioactive compounds, are reshaping how individuals approach general wellness, age-related health challenges, and chronic disease prevention. Increased consumer awareness and rising investments in longevity-focused research are key factors fueling the market’s growth.

Integrating innovations such as personalized nutrition, wearable health technologies, and AI-driven supplement recommendations further accelerates the adoption of targeted wellness solutions. These advancements enable brands to offer tailored products that address individual nutritional needs and lifestyle factors, promoting optimal health outcomes and consumer engagement.

The market’s growth is also driven by the increasing application of longevity and wellness supplements across various demographics, including active aging populations, fitness enthusiasts, and health-conscious millennials. The demand for plant-based, clean-label, and scientifically validated supplements has created a strong push for formulation and delivery systems innovation. With evolving regulatory landscapes and consumer preferences, companies are expanding their product portfolios and investing in cutting-edge R&D to ensure efficacy, safety, and transparency.

As longevity and general wellness trends evolve, the U.S. supplements market is poised to transform preventive healthcare, support healthy aging, and empower individuals to take control of their long-term well-being.

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U.S. Longevity & General Wellness Supplements Market Report Highlights

• The general wellness supplement segment led the U.S. longevity and wellness supplements market in 2025, driven by rising preventive health awareness and demand for immunity, stress relief, and clean-label, plant-based products.

• The longevity supplements segment is projected to grow at the fastest CAGR, driven by rising interest in healthy aging and advances in science-backed ingredients such as NAD? boosters, senolytics, and adaptogens.

U.S. Longevity & General Wellness Supplements Market Segmentation

Grand View Research has segmented the U.S. longevity and general wellness supplements market based on application:

U.S. Longevity & General Wellness Supplements Application Outlook (Revenue, USD Million, 2021 - 2033)

• Longevity Supplements

  • Type

    • NMN

    • NR

    • NAD+

    • NADH

    • Resveratrol

    • Fisetin

    • Quercetin

    • Cucurmin

    • Collagen

    • Pterostilbene

    • Others

  • Sales Channel

    • Online

      • Direct to consumer

      • Other e-commerce channels

    • Offline

      • Hypermarkets/Supermarkets

      • Pharmacies & Drug Stores

      • Others

• General Wellness Supplements

  • Type

    • Vitamins

    • Multivitamins

    • Individual vitamins

    • Minerals

    • Amino acids

    • Probiotics

    • Collagen

    • Fish oils

    • Coenzyme Q10

    • Herbal extracts

    • Others

  • Sales Channel

    • Online

      • Direct to consumer

      • Other e-commerce channels

    • Offline

      • Hypermarkets/Supermarkets

      • Pharmacies & Drug Stores

      • Others

List of Key Players in the U.S. Longevity & General Wellness Supplements Market

• NOW Foods

• Life Extension

• Nature’s Bounty

• Jarrow Formulas

• Nature’s Way

• Thorne

• Himalaya Wellness (US)

• Pure Encapsulations

• Hims & Hers Health, Inc.

• Ro

• Elysium Health

• Niagen Bioscience

• ProHealth

• RevGenetics

• Codeage LLC