The global dental bone void filler market size was valued at USD 82.8 million in 2020 and is expected to grow at a compound annual growth rate (CAGR) of 5.6% from 2021 to 2028. This growth can be attributed to the increasing number of synthetic products. Synthetic fillers include tri-calcium phosphates and calcium sulfate that has advantages, such as there is no risk of any disease transference and has a relatively long shelf life. Bone grafting has become a common technique in surgical practice. The market for dental bone void filler is increasing due to the advantages of the material that is being used. For instance, tricalcium phosphate ceramics have osteoconduction, good resorbability, ease of handling, and radiopacity allowing monitored healing.
These factors boost the demand for tricalcium phosphate ceramics thereby, driving the market. Bioceramics are inorganic biomaterials, such as bioactive glass and calcium phosphate bioceramics that have applications as bone void fillers in the dental field. Bioceramics are attracting more attention in dental reconstruction due to their bioactivity, hydrophilicity, osteoconductivity, easy availability, excellent biocompatibility, potential osteoinductivity, and similarity to native bone inorganic components. These characteristics of bio-ceramics are expected to increase the demand for dental bone void filler materials thus propelling the market growth.
Technological advancements, such as 3D scaffolds of bone graft substitutes, have been recently introduced in the dental industry to overcome the drawbacks of routinely employed grafting materials. Bone tissue engineering has developed a new technology for regeneration through the introduction of scaffolds that poses three-dimensional architecture that closely mimics the native extracellular matrix. Such arrangement eventually enhances cell differentiation, proliferation and adhesion, and overall tissue regeneration. This application and the properties of advanced technology drive the market.
Furthermore, the COVID-19 pandemic harmed the dental industry in 2020. As per the COVID-19 guidelines released by several government bodies across the globe, dental settings were recommended to focus only on emergency & urgent visits and postpone all elective visits. Thus, reducing the patient influx and negatively impacting the revenue of dental practitioners. Moreover, dental practitioners are at a high risk of contracting COVID- 19, especially while carrying out aerosol-generating procedures in their practice settings. This, in turn, is anticipated to have led to increased fear among these professionals, making them skeptical to provide treatment and further reducing the patient influx. However, dentistry is considered to be an essential practice, and the service has been able to remain open despite lockdowns across various regions globally.
The Demineralized Bone Matrix (DBM) segment held the highest share of 25% in 2020. This can be attributed to the high popularity of the material among dental professionals and the rising complexity of bone grafting procedures leading to the increasing demand for demineralized bone matrix. For instance, Grafton demineralized bone matrix is the most commonly utilized brand that is designed to replace or extend autogenous bone in various challenging bone grafting procedures.
Grafton is a bone graft substitute, bone void filler, and bone graft extender of the skeletal system not intrinsic to the stability of the bone structure. Grafton inject is a demineralized bone allograft that consists of demineralized cortical fibers that are derived from a cadaveric donor. The grafts come with a pre-loaded syringe with minimally invasive procedure accessories. This allows the product to be delivered through most retractor systems and helps facilitate any bone voids where union or fusion is desired. Such characteristics of Grafton are expected to increase the demand for demineralized bone matrix, thus boosting the segment growth.
Based on material, the market is broadly categorized into tricalcium phosphate ceramics, biphasic calcium phosphate ceramics, calcium phosphate cements, calcium sulfates, demineralized bone matrix, and others. The others segment primarily includes composite materials and hydroxyapatite. The others segment is anticipated to witness the fastest CAGR over the forecast period due to the ability of composites to combine the advantages and characteristics of various materials, such as relatively better bioactivity, biocompatibility, bio absorbability, and osteoconductive.
Europe dominated the global market in 2020 accounting for nearly 40.0% of the overall revenue share. The major factors contributing to market growth include an increase in the geriatric population, a high prevalence of oral diseases, and a high rate of tooth extractions in the region. Supportive initiatives by market players are also expected to drive the market. For instance, in 2021, Curasan AG expanded its distribution network in Europe, thereby facilitating market growth in the region.
Asia Pacific is anticipated to witness lucrative growth over the forecast period. This can be attributed to the high patient pool leading to high demand for dental treatments. Moreover, rapidly developing oral care infrastructure in emerging markets like India supports the region’s growth. For instance, with over 297 dental institutes and 5000 dental laboratories in India, the country is one of the largest markets for dental care in the region. Various major players, such as Wockhardt, Fortis, and Apollo Group, are setting up a chain of dental clinics to grow the dental market. Such factors are expected to drive the regional market.
The market is highly competitive with the presence of many domestic as well as international players. Key companies are investing in new products and technological developments, which is propelling market growth.
For instance, in March 2019, Medtronic launched Grafton that is a demineralized bone matrix bone grafting product, in Japan. It serves the three-pronged purpose as bone graft substitute, bone void filler, and bone graft extender. This launch has expanded the company’s product offerings in the country. Some of the key companies in the global dental bone void filler market are:
Olympus Terumo Biomaterials Corp.
DePuy Synthes Companies (JnJ)
Market size value in 2021
USD 86.9 million
Revenue forecast in 2028
USD 127.0 million
CAGR of 5.6% from 2021 to 2028
Base year for estimation
2016 - 2019
2021 - 2028
Revenue in USD million/billion and CAGR from 2021 to 2028
Revenue forecast, company ranking, competitive landscape, growth factors, and trends
Material type, region
North America; Europe; Latin America; Asia Pacific; MEA
U.S.; Canada; U.K.; Germany; France; Italy; Spain; China; Japan; India; Australia; South Korea; Brazil; Mexico; Argentina; South Africa; Saudi Arabia; UAE
Key companies profiled
Curasan, Inc.; Olympus Terumo Biomaterials Corp.; Medtronic; GRAFTYS; DePuy Synthes Companies (JnJ); Stryker
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This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2016 to 2028. For the purpose of this report, Grand View Research has segmented the global dental bone void filler market report on the basis of material type and region:
Material Type Outlook (Revenue, USD Million, 2016 - 2028)
Tricalcium Phosphate Ceramics
Biphasic Calcium Phosphate Ceramics
Calcium Phosphate Cements
Demineralized Bone Matrix (DBM)
Regional Outlook (Revenue, USD Million, 2016 - 2028)
Middle East & Africa
b. The global dental bone void filler market size was valued at USD 82.8 million in 2020 and is expected to reach USD 86.9 million in 2021.
b. The global dental bone void filler market is expected to grow at a compound annual growth rate of 5.6% from 2021 to 2028 to reach USD 127.0 million by 2028.
b. North America dominated the dental bone void filler market with a share of 38.0% in 2020. The major factors contributing to market growth include an increase in the geriatric population, a high prevalence of oral diseases, and a high rate of tooth extractions in the region.
b. Some key players operating in the dental bone void filler market include Curasan, Inc., Olympus Terumo Biomaterials Corporation, Medtronic, GRAFTYS, DePuy Synthes Companies (JnJ), Stryker.
b. Key factors that are driving the dental bone void filler market growth include the increasing number of synthetic products, availability of advanced materials such as hydroxyapatite & technological advancement.
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