Hemostasis & Tissue Sealing Agents Market Size, Share & Trends Analysis Report By Product (Topical Hemostat, Adhesive & Tissue Sealant), By Material, By Application, By End-use, By Region, And Segment Forecasts, 2024 - 2030

Research Methodology

A three-pronged approach was followed for deducing the hemostasis & tissue sealing agents market estimates and forecasts. The process has three steps: information procurement, analysis, and validation. The whole process is cyclical, and steps repeat until the estimates are validated. The three steps are explained in detail below:

Information procurement: Information procurement is one of the most extensive and important stages in our research process, and quality data is critical for accurate analysis. We followed a multi-channel data collection process for hemostasis & tissue sealing agents market to gather the most reliable and current information possible.

• We buy access to paid databases such as Hoover’s and Factiva for company financials, industry information, white papers, industry journals, SME journals, and more.
• We tap into Grand View’s proprietary database of data points and insights from active and archived monitoring and reporting.
• We conduct primary research with industry experts through questionnaires and one-on-one phone interviews.
• We pull from reliable secondary sources such as white papers and government statistics, published by organizations like WHO, NGOs, World Bank, etc., Key Opinion Leaders (KoL) publications, company filings, investor documents, and more.
• We purchase and review investor analyst reports, broker reports, academic commentary, government quotes, and wealth management publications for insightful third-party perspectives.

Analysis: We mine the data collected to establish baselines for forecasting, identify trends and opportunities, gain insight into consumer demographics and drivers, and so much more. We utilized different methods of hemostasis & tissue sealing agents market data depending on the type of information we’re trying to uncover in our research.

• Market Research Efforts: Bottom-up Approach for estimating and forecasting demand size and opportunity, top-down Approach for new product forecasting and penetration, and combined approach of both Bottom-up and Top-down for full coverage analysis.

• Value-Chain-Based Sizing & Forecasting: Supply-side estimates for understanding potential revenue through competitive benchmarking, forecasting, and penetration modeling.

• Demand-side estimates for identifying parent and ancillary markets, segment modeling, and heuristic forecasting.

• Qualitative Functional Deployment (QFD) Modelling for market share assessment.

Market formulation and validation: We mine the data collected to establish baselines for forecasting, identify trends and opportunities, gain insight into consumer demographics and drivers, and so much more. We utilize different methods of data analysis depending on the type of information we’re trying to uncover in our research.

• Market Formulation: This step involves the finalization of market numbers. This step on an internal level is designed to manage outputs from the Data Analysis step.

• Data Normalization: The final market estimates and forecasts are then aligned and sent to industry experts, in-panel quality control managers for validation.

• This step also entails the finalization of the report scope and data representation pattern.

• Validation: The process entails multiple levels of validation. All these steps run in parallel, and the study is forwarded for publishing only if all three levels render validated results.

Hemostasis & Tissue Sealing Agents Market Categorization:

The hemostasis & tissue sealing agents market was categorized into four segments, namely product (Topical Hemostat, Adhesive & Tissue Sealant), material (Gelatin-based Topical Hemostats, Collagen-based Topical Hemostats, ORC-based Topical Hemostats, Polysaccharide-based Topical Hemostats), application (General Surgery, Neurosurgery, Vascular Surgery, Cardiovascular Surgery),end-use (Hospitals, Ambulatory Surgical Centers), and regions (North America, Europe, Asia Pacific, Latin America, Middle East & Africa).

Segment Market Methodology:

The hemostasis & tissue sealing agents market was segmented into product, application, end-use, and regions. The demand at a segment level was deduced using a funnel method. Concepts like the TAM, SAM, SOM, etc., were put into practice to understand the demand. We at GVR deploy three methods to deduce market estimates and determine forecasts. These methods are explained below:

Market research approaches: Bottom-up

• Demand estimation of each product across countries/regions summed up to from the total market.

• Variable analysis for demand forecast.

• Demand estimation via analyzing paid database, and company financials either via annual reports or paid database.

• Primary interviews for data revalidation and insight collection.

Market research approaches: Top-down

• Used extensively for new product forecasting or analyzing penetration levels.

• Tool used invoice product flow and penetration models Use of regression multi-variant analysis for forecasting Involves extensive use of paid and public databases.

• Primary interviews and vendor-based primary research for variable impact analysis.

Market research approaches: Combined

• This is the most common method. We apply concepts from both the top-down and bottom-up approaches to arrive at a viable conclusion.

Regional Market Methodology:

The hemostasis & tissue sealing agents market was analyzed at a regional level. The globe was divided into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa, keeping in focus variables like consumption patterns, export-import regulations, consumer expectations, etc. These regions were further divided into twenty-three countries, namely, the U.S.; Canada; UK; Germany; France; Italy; Spain; Denmark; Sweden; Norway; Japan; China; India; Australia; Thailand; South Korea; Brazil; Mexico; Argentina; South Africa; Saudi Arabia; UAE; Kuwait

All three above-mentioned market research methodologies were applied to arrive at regional-level conclusions. The regions were then summed up to form the global market.

Hemostasis & tissue sealing agents market companies & financials:

The hemostasis & tissue sealing agents market was analyzed via companies operating in the sector. Analyzing these companies and cross-referencing them to the demand equation helped us validate our assumptions and conclusions. Key market players analyzed include:

• Johnson & Johnson Johnson & Johnson, an American publicly held multinational company, is a major player in the global market. With over 265 subsidiaries in approximately 60 countries and a customer base in over 175 countries, the company operates in the pharmaceuticals, consumer products, and medical equipment sectors. It offers a wide range of pharmaceuticals for various conditions, including blood disorders, neurological diseases, cancer, pain, and autoimmune diseases. The company's subsidiary, Ethicon, is known for manufacturing wound closure devices and surgical sutures. Johnson & Johnson, incorporated in 1949 in the U.S., is a significant market force, serving clients in over 50 countries. 

• CryoLife, Inc. CryoLife, Inc. is a prominent market player in the medical industry, recognized for its innovative medical devices and human tissue processing. The company specializes in the processing and distribution of human tissues for application in cardiac surgeries. With sales offices in over 75 countries and a team of more than 500 employees, CryoLife has a strong global presence. One of its notable contributions to the healthcare field is the SynerGraft Process, a product that has made a significant impact. The company's product portfolio encompasses a wide range of offerings, including cardiac tissues, CardioGenesis cardiac laser therapy, vascular tissues, surgical adhesives, and the ProCol vascular bioprosthesis.

• Advanced Medical Solutions (AMS) Group plc Advanced Medical Solutions (AMS) Group plc, a publicly held organization based in the UK, is a significant player in the global market. The company, which was listed on the stock market in 1994, operates in three key business segments: wound management products, sealants & tissue closure products, and products reducing surgical adverse effects. AMS markets its products under three major brands: Resorba, LiquiBand, and ActivHeal. With manufacturing units in five countries, the company has established a strong international presence.

• Cohera Medical Inc. Cohera Medical Inc. is a privately held organization that specializes in the development of synthetic surgical sealants and adhesives. Established in 2003 and headquartered in the U.S., the company has a niche product portfolio that includes component adhesives such as hernia mesh fixations. Cohera Medical has recently entered the European market with its latest technologies and products, including TissuGlu and Sylys.

• Integra LifeSciences Corporation Integra LifeSciences Corporation, established in 1989 and headquartered in the U.S., is a major player in the wound management market. The publicly held company has a global marketing channel of direct sales and distributors and specializes in the development of biological implants such as wound dressings and grafts for spine, brain, and other orthopedic surgeries to generate new tissues, bones, and nerves. Integra offers innovative solutions in neurosurgery, spine surgery, orthopedic extremity surgery, and reconstructive & general surgery. 

• Pfizer Inc. Pfizer Inc., a U.S.-based pharmaceutical company, has been a major player in the global pharmaceutical market since its incorporation in 1849. The company is known for manufacturing a wide range of products for the treatment of various conditions, including diabetes, immunological, cardiological, oncology, and dermatological ailments. Pfizer has solidified its position in the industry through strategic alliances with key players such as Johnson & Johnson, Merck, GE Healthcare, Novartis, F. Hoffmann-La Roche Ltd, and Bayer AG to enhance its market share. 

• C.R Bard Inc. C. R. Bard, Inc., a publicly operated medical equipment manufacturing company, has been a significant player in the global market since its establishment in 1907. Headquartered in the U.S., the company is known for its diverse portfolio of medical devices, including surgical, patient care, and diagnostic devices. C. R. Bard's offerings span various medical specialties, such as urology, vascular, surgical, and oncology products. The company caters to a wide range of sectors, including individual healthcare professionals, hospitals, and extended care facilities, and operates in regions such as North America, Asia Pacific, Europe, the Middle East, and Africa. With manufacturing units in Germany, Puerto Rico, Belgium, France, Malaysia, and Mexico, C. R. Bard has established a strong global presence. 

• Cohesion Technologies Cohesion Technologies Inc. is a U.S.-based medical device company that specializes in the development, research, and marketing of medical biodevices used in adhesive technologies and tissue regeneration systems. The company's most popular products include CoStasis, a surgical hemostat used to control blood loss in surgeries such as general, gastrointestinal, and urological, and CoSeal, a tissue sealant used in trauma surgeries to prevent fluid loss and eliminate exudation. 

• HyperBranch Medical Technology, Inc. HyperBranch Medical Technology, Inc. is a privately held medical device manufacturing company headquartered in the U.S. The company was incorporated in 2003 with the goal of creating biosurgical sealants to reduce the mortality rate of patients during surgeries. HyperBranch Medical Technology specializes in the development of surgically induced wound management devices and trauma-induced wound management, particularly for neurological, ophthalmic, and hernia surgeries. The company's primary products include OcuSeal, Adherus Dural Sealant, Adherus Vascular Sealant, and NuSeal 30 hernia mesh fixation device. 

• Biomet Inc. Zimmer Biomet, formerly known as Biomet Inc., is a global medical technology leader with a comprehensive portfolio designed to maximize mobility and improve health. The company has been a driving force in the rapidly growing musculoskeletal healthcare industry for nearly 90 years. Zimmer Biomet focuses on alleviating pain and improving the quality of life for people around the world. The company manufactures and markets effective, innovative solutions that support orthopedic surgeons and clinicians in restoring mobility, alleviating pain, and improving the quality of life for patients around the world. Zimmer Biomet has operations in more than 25 countries around the world and sells products in more than 100 countries. 

Value chain-based sizing & forecasting

Supply Side Estimates

• Company revenue estimation via referring to annual reports, investor presentations, and Hoover’s.

• Segment revenue determination via variable analysis and penetration modeling.

• Competitive benchmarking to identify market leaders and their collective revenue shares.

• Forecasting via analyzing commercialization rates, pipelines, market initiatives, distribution networks, etc.

Demand side estimates

• Identifying parent markets and ancillary markets

• Segment penetration analysis to obtain pertinent

• revenue/volume

• Heuristic forecasting with the help of subject matter experts

• Forecasting via variable analysis

Hemostasis & Tissue Sealing Agents Market Report Objectives:

• Understanding market dynamics (in terms of drivers, restraints, & opportunities) in the countries.

• Understanding trends & variables in the individual countries & their impact on growth and using analytical tools to provide high-level insights into the market dynamics and the associated growth pattern.

• Understanding market estimates and forecasts (with the base year as 2023, historic information from 2018 - 2023, and forecast from 2024 to 2030). Regional estimates & forecasts for each category are available and are summed up to form the global market estimates.

Hemostasis & Tissue Sealing Agents Market Report Assumptions:

• The report provides market value for the base year 2023 and a yearly forecast till 2030 in terms of revenue/volume or both. The market for each of the segment outlooks has been provided on region & country basis for the above-mentioned forecast period.

• The key industry dynamics, major technological trends, and application markets are evaluated to understand their impact on the demand for the forecast period. The growth rates were estimated using correlation, regression, and time-series analysis.

• We have used the bottom-up approach for market sizing, analyzing key regional markets, dynamics, & trends for various products and end-users. The total market has been estimated by integrating the country markets.

• All market estimates and forecasts have been validated through primary interviews with the key industry participants.

• Inflation has not been accounted for to estimate and forecast the market.

• Numbers may not add up due to rounding off.

• Europe consists of EU-8, Central & Eastern Europe, along with the Commonwealth of Independent States (CIS).

• Asia Pacific includes South Asia, East Asia, Southeast Asia, and Oceania (Australia & New Zealand).

• Latin America includes Central American countries and the South American continent

• Middle East includes Western Asia (as assigned by the UN Statistics Division) and the African continent.

Primary Research

GVR strives to procure the latest and unique information for reports directly from industry experts, which gives it a competitive edge. Quality is of utmost importance to us, therefore every year we focus on increasing our experts’ panel. Primary interviews are one of the critical steps in identifying recent market trends and scenarios. This process enables us to justify and validate our market estimates and forecasts to our clients. With more than 8,000 reports in our database, we have connected with some key opinion leaders across various domains, including healthcare, technology, consumer goods, and the chemical sector. Our process starts with identifying the right platform for a particular type of report, i.e., emails, LinkedIn, seminars, or telephonic conversation, as every report is unique and requires a differentiated approach.

We send out questionnaires to different experts from various regions/ countries, which is dependent on the following factors:

• Report/Market scope: If the market study is global, we send questionnaires to industry experts across various regions, including North America, Europe, Asia Pacific, Latin America, and MEA.

• Market Penetration: If the market is driven by technological advancements, population density, disease prevalence, or other factors, we identify experts and send out questionnaires based on region or country dominance.

The time to start receiving responses from industry experts varies based on how niche or well-penetrated the market is. Our reports include a detailed chapter on the KoL opinion section, which helps our clients understand the perspective of experts already in the market space.