Peptide Synthesis Market Size, Share & Trends Analysis Report By Product (Equipment, Reagents & Consumables), By Application (Therapeutics, Diagnosis), By Technology, By End Use, By Region, And Segment Forecasts, 2024 - 2030

Peptide Synthesis Market Size & Trends

The global peptide synthesis market size was valued at USD 608.0 million in 2023 and is projected to grow at a CAGR of 12.7% from 2024 to 2030. Market growth is attributed to factors such as increasing demand for peptide-based therapeutics, expanding applications in diagnostics and imaging, advancement in therapeutics for rare diseases, personalized medicine, and precision therapeutics. Moreover, the market growth is increasing due to higher genetic activity, wide-ranging chemicals, low toxicity, and high specificity.

The growing prevalence of chronic diseases such as cancer, diabetes, and cardiovascular disorders is boosting the demand for peptide-based drugs, which are known for their high specificity and low toxicity. This demand is coupled with advancements in peptide synthesis technologies, enabling the efficient production of these therapeutics. The trend towards personalized medicine, where treatments are tailored to individual genetic profiles, also enhances the need for peptide synthesis.

According to an International Journal of Molecular Sciences study, over 400 peptide drugs are in clinical trials, and more than 60 have been approved worldwide for managing various chronic conditions such as cancer, chronic pain, diabetes, and HIV infection. The industry is seeing a surge in adoption for the treatment of neurological disorders and cardiovascular and renal diseases, with a growing number of peptide-based therapies being developed to address these complex conditions.

In addition to the growing demand for peptide-based therapeutics, the market is also driven by the expansion of diagnostic applications. Peptides are increasingly utilized in diagnostic tools, including biosensors and imaging agents, which further propels market growth. Furthermore, research activities aimed at finding new therapeutic peptides are increasing, fueled by government funds and the development of new technologically effective peptide synthesizers. As a result, the peptide synthesis market is expected to continue growing as the demand for low-cost drugs increases and more disease incidences rise.

Product Insights

The reagents and consumables in the product segment dominated the peptide synthesis market with a revenue share of 47.4% in 2023, aided by their customization, flexibility, and wide range of products. As essential components, they play a crucial role in the peptide synthesis process, including amino acids, coupling reagents, resins, solvents, and protecting groups. Their absence would render peptide synthesis impossible, making them a vital component of the industry.

The equipment segment is expected to register the fastest CAGR of 13.2% during the forecast period, driven by its scalability and versatility. Depending on the level of specialization and experiment requirements, equipment can be tailored to meet specific needs. Its ability to produce high-quality peptides in large quantities, while maintaining control over production volumes, is critical in addressing the increasing demand for peptides across various applications, fueling the growth of the equipment segment.

Technology Insights

The liquid phase peptide synthesis (LPPS) in the technology segment dominated the peptide synthesis market with a revenue share of 44.4% in 2023. The dominance is attributed to its efficiency, scalability, high purity and quality, flexibility, customization, and cost-effectiveness. LPPS yields high-quality peptides with fewer impurities, allowing for precise control over reaction conditions. This results in superior product quality compared to other synthesis methods, making it the preferred choice for researchers and manufacturers seeking optimal results.

The hybrid technology segment in the peptide synthesis market is expected to register the fastest CAGR of 14.7% during the forecast period. Segment growth is driven by technological advancements, market demand, and the versatility of peptide synthesis technology. Hybrid approaches enable high-purity and high-yield peptide production, critical in pharmaceutical applications where quality is paramount. Automation and continuous innovation have also improved synthesis speed and performance, making it a preferred choice for research institutions and industries.

Application Insights

Therapeutics dominated the market with a revenue share of 70.3% in 2023. The therapeutics application segment has experienced significant growth, driven by the demand for peptide therapeutics offering improved metabolic stability, target specificity, and affinity. To address capacity, production, and manufacturing challenges, large pharma and biotech companies are increasingly outsourcing peptide synthesis to contract manufacturers, fueling the growth of this segment.

The diagnosis in application segment in the peptide synthesis market is expected to register the fastest CAGR of 13.7% during the forecast period. Peptides in diagnostic assays demonstrate exceptional specificity and sensitivity, enabling precise identification of targeted molecules. This precision is critical, as results inform critical treatment decisions. Advances in peptide synthesis have boosted yields and quantities, expanding their applications in diagnostics. Enhanced availability and performance of diagnostic peptides drive innovation and adoption in the industry.

End Use Insights

The pharmaceutical & biotechnology companies led the market with a revenue share of 69.7% in 2023. These companies have established a robust infrastructure, expertise, and financial support for drug research and development. Equipped with specialized labs, skilled personnel, and advanced tools for peptide synthesis, they remain at the forefront of discovering new peptides with therapeutic potential. By prioritizing innovation, they aim to uphold their position as industry leaders in developing peptide-based drugs for diverse medical conditions.

The Contract Development & Manufacturing Organization/ Contract Research Organization (CDMOs / CROs) in end use segment in the peptide synthesis market is expected to register the fastest CAGR of 13.4% during the forecast period. CDMOs and CROs are service providers that offer specialized expertise and facilities needed by pharmaceutical and biotech companies, as well as academic and research institutions, to carry out drug development and production processes. The demand for CDMOs and CROs is increasing due to they are well-equipped to handle outsourced contract work. One of the services these organizations provide is peptide synthesis, which is valuable for companies involved in drug development, manufacturing, and research.

Regional Insights

North America peptide synthesis market dominated the global peptide synthesis market with a revenue share of 37.4% in 2023. The dominance can be attributed to its highly developed pharmaceutical sector, well-developed technology, favorable regulations, and a relatively greater focus on the biopharmaceutical industry.

U.S. Peptide Synthesis Market Trends

Peptide synthesis market in the U.S. dominated the North America peptide synthesis market with a revenue share of 91.8% in 2023. Market growth in the country is aided by several key factors. The increasing prevalence of chronic diseases such as diabetes and obesity is driving demand for peptide-based therapeutics, while investments in research and development of personalized medicines and advanced synthesis technologies are also contributing to the market’s growth.

Europe Peptide Synthesis Market Trends

Europe peptide synthesis market is expected to grow in the forecast period. The market for peptide synthesis has been driven by the biopharmaceutical industry, research institutes, and government support for scientific advancement. The approval of BiP-peptide programs by organizations such as the FDA has played a crucial role in promoting the market for peptide-based drugs in Europe.

Peptide synthesis market in the UK is expected to grow rapidly in the coming years due to significant investment in research and development activities. This growth is being fueled by an increase in chronic diseases and the presence of a strong biochemical industry. Moreover, other contributing factors include the growth of urbanization, improvements in healthcare infrastructure, and diversification within the manufacturing segment.

Germany peptide synthesis market held a substantial market share in 2023. Germany is a prominent player in the international pharmaceutical market with well-developed research and production. The country is home to many large-scale pharmaceutical industries that specialize in peptides and associated technologies, making it a leading market for peptide synthesis worldwide.

Asia Pacific Peptide Synthesis Market Trends

Peptide synthesis market in Asia Pacific is expected to register the fastest growth with a CAGR of 14.6% in the forecast period. It is cheaper to undertake manufacturing in Asian Pacific countries than in the developed western countries. This aspect of reduced cost has made pharmaceutical companies view the outsourcing synthesis of peptides as a means of cutting on unnecessary expenses hence the increased demand for CMOs in the region.

China peptide synthesis market is expected to grow in the forecast period. Chinese companies have significantly increased their investments in synthesizing peptides and improving process technologies. This has allowed them to expand their production and make peptide drugs available to markets worldwide driving growth of the market.

Peptide synthesis market in India has a significant share in the Asia Pacific peptide synthesis market. India has cost-effective production facilities for synthesizing peptides, with relatively low labor and operating costs leading to affordable peptide synthesis services. There has been heavy investment in research and development activities focused on peptides and other biologics. This growth has driven the peptide synthesis market in India.

Key Peptide Synthesis Company Insights

Some key companies in the peptide synthesis market include Thermo Fisher Scientific Inc.; Merck KGaA; GenScript; and others. Key strategies involve launching and approving innovative peptide-based therapeutics and diagnostics to expand portfolios. The companies are also partnering with research institutions and biotech firms to leverage expertise and accelerate commercialization of new products, fostering growth and diversification.

• Thermo Fisher Scientific Inc. serves as a global provider in providing a diverse range of products and services, including analytical devices, medical development solutions, diagnostic expertise, laboratory equipment, pharmaceutical services, and biotechnology offerings. They offer flexible synthesis options and purity levels, driving innovation through novel technologies and strategic acquisitions to maintain market dominance in peptide-based therapeutics and diagnostics.

• Bachem Holding AG specializes in developing and manufacturing peptides and complex molecules for research and pharmaceutical applications. They offer both generic and proprietary APIs, catering to the pharmaceutical industry’s needs in oncology, diabetes, and obesity treatments. Bachem prioritizes innovation, quality, and sustainability, investing in R&D and strategic partnerships.

Recent Developments

• In July 2023, Merck announced an agreement to gather the peptide synthesis corporation Asymchem. This strategic move is geared toward enhancing Merck’s talents in peptide synthesis and increasing its global manufacturing network.

• In May 2023, PolyPeptide Group announced a partnership with Numaferm, a biotechnology business enterprise known for its advanced fermentation technology. This partnership aimed to leverage the strengths of both organizations to enhance their competencies in peptide manufacturing and boost the improvement of novel peptide-based therapeutics.

Peptide Synthesis Market Report Scope

Global Peptide Synthesis Market Report Segmentation

This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2018 to 2030. For this study, Grand View Research has segmented the global peptide synthesis market report based on product, application, technology, end use, and region.

• Product Outlook (Revenue, USD Million, 2018 - 2030)

  • Equipment

    • Peptide Synthesizers

    • Lyophilizers

    • Chromatography Equipment

    • Others

  • Reagents & Consumables

    • Resins

    • Amino Acids

    • Coupling Reagents

    • Dyes & Fluroscent Labeling Reagents

    • Others

  • Services

• Technology Outlook (Revenue, USD Million, 2018 - 2030)

  • Solid Phase Peptide Synthesis (SPPS)

  • Liquid Phase Peptide Synthesis (LPPS)

  • Hybrid Technology

• Application Outlook (Revenue, USD Million, 2018 - 2030)

  • Therapeutics

    • Cancer

    • Metabolic

    • Cardiovascular Disorder

    • Respiratory

    • GIT (Gastrointestinal Disorders)

    • Infectious Diseases

    • Pain

    • Dermatology

    • CNS

    • Renal

    • Others

  • Diagnosis

  • Research

• End Use Outlook (Revenue, USD Million, 2018 - 2030)

  • Pharmaceutical & Biotechnology Companies

  • Contract Development & Manufacturing Organization/Contract Research Organization

  • Academic & Research Institutes

• Regional Outlook (Revenue, USD Million, 2018 - 2030)

  • North America

    • U.S.

    • Canada

    • Mexico

  • Europe

    • UK

    • Germany

    • France

    • Italy

    • Spain

    • Denmark

    • Sweden

    • Norway

  • Asia Pacific

    • Japan

    • China

    • India

    • Australia

    • South Korea

    • Thailand

  • Latin America

    • Brazil

    • Argentina

  • Middle East & Africa

    • South Africa

    • Saudi Arabia

    • UAE

    • Kuwait