A three-pronged approach was followed for deducing the primary cell culture market estimates and forecasts. The process has three steps: information procurement, analysis, and validation. The whole process is cyclical, and steps repeat until the estimates are validated. The three steps are explained in detail below:
Information procurement: Information procurement is one of the most extensive and important stages in our research process, and quality data is critical for accurate analysis. We followed a multi-channel data collection process for primary cell culture market to gather the most reliable and current information possible.
Analysis: We mine the data collected to establish baselines for forecasting, identify trends and opportunities, gain insight into consumer demographics and drivers, and so much more. We utilized different methods of primary cell culture market data depending on the type of information we’re trying to uncover in our research.
Market Research Efforts: Bottom-up Approach for estimating and forecasting demand size and opportunity, top-down Approach for new product forecasting and penetration, and combined approach of both Bottom-up and Top-down for full coverage analysis.
Value-Chain-Based Sizing & Forecasting: Supply-side estimates for understanding potential revenue through competitive benchmarking, forecasting, and penetration modeling.
Demand-side estimates for identifying parent and ancillary markets, segment modeling, and heuristic forecasting.
Qualitative Functional Deployment (QFD) Modelling for market share assessment.
Market formulation and validation: We mine the data collected to establish baselines for forecasting, identify trends and opportunities, gain insight into consumer demographics and drivers, and so much more. We utilize different methods of data analysis depending on the type of information we’re trying to uncover in our research.
Market Formulation: This step involves the finalization of market numbers. This step on an internal level is designed to manage outputs from the Data Analysis step.
Data Normalization: The final market estimates and forecasts are then aligned and sent to industry experts, in-panel quality control managers for validation.
This step also entails the finalization of the report scope and data representation pattern.
Validation: The process entails multiple levels of validation. All these steps run in parallel, and the study is forwarded for publishing only if all three levels render validated results.
The primary cell culture market was categorized into four segments, namely product (Primary Cells, Reagents & Supplements, Media), separation method (Explant Method, Enzymatic Degradation, Mechanical Separation), cell type (Animal Cells, Human Cells), application (Cell & Gene Therapy Development, Vaccine Production, Model System, Virology, Prenatal Diagnosis), and regions (North America, Europe, Asia Pacific, Latin America, Middle East & Africa).
The primary cell culture market was segmented into product, separation method, cell type, application, and regions. The demand at a segment level was deduced using a funnel method. Concepts like the TAM, SAM, SOM, etc., were put into practice to understand the demand. We at GVR deploy three methods to deduce market estimates and determine forecasts. These methods are explained below:
Demand estimation of each product across countries/regions summed up to from the total market.
Variable analysis for demand forecast.
Demand estimation via analyzing paid database, and company financials either via annual reports or paid database.
Primary interviews for data revalidation and insight collection.
Used extensively for new product forecasting or analyzing penetration levels.
Tool used invoice product flow and penetration models Use of regression multi-variant analysis for forecasting Involves extensive use of paid and public databases.
Primary interviews and vendor-based primary research for variable impact analysis.
The primary cell culture market was analyzed at a regional level. The globe was divided into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa, keeping in focus variables like consumption patterns, export-import regulations, consumer expectations, etc. These regions were further divided into twenty-three countries, namely, the U.S.; Canada; Germany; the UK; France; Italy; Spain; Denmark; Sweden; Norway; China; Japan; India; South Korea; Australia; Thailand; Brazil; Mexico, Argentina; South Africa; Saudi Arabia, UAE; and Kuwait.
All three above-mentioned market research methodologies were applied to arrive at regional-level conclusions. The regions were then summed up to form the global market.
The primary cell culture market was analyzed via companies operating in the sector. Analyzing these companies and cross-referencing them to the demand equation helped us validate our assumptions and conclusions. Key market players analyzed include:
MERCK - Merck is a German multinational company involved in provision of healthcare solutions and materials. It operates in three sectors: healthcare, life sciences, and performance materials. It has worldwide operations in North America, Europe, Asia, Latin America, Oceania, and Africa. In November 2015, Merck announced the acquisition of Sigma Aldrich Co. LLC, which began operating as a subsidiary of Merck KGaA.
THERMO FISHER SCIENTIFIC, INC. - Thermo Fisher Scientific, Inc. is a developer and supplier of analytical equipment, instruments, consumables, reagents, software, and services for various applications, including diagnostics, research, manufacturing, and drug discovery. The company operates across four business segments: analytical instruments, specialty diagnostics, life sciences solutions, and laboratory products & services. Through the specialty diagnostics segment, it provides diagnostic reagents, test kits, instruments, culture media, and associated products to serve customers in healthcare, clinical, pharmaceutical, industrial, & food safety laboratories.
DANAHER CORPORATION - Danaher designs, manufactures, and commercializes products as well as services catering to medical, professional, and commercial applications. The company operates through four segments: diagnostics, life sciences, environmental & applied solutions, and dental solutions. Danaher's diagnostics segment offers reagents, analytical instruments, software, consumables, and services to diagnose various diseases for physicians' offices, hospitals, reference laboratories, & other critical care settings. Danaher has facilities in more than 60 countries. In March 2020, the company completed acquisition of Cytiva-a General Electric Company's Life Sciences division.
LONZA - Lonza is a worldwide supplier of biopharmaceuticals. The company offers a variety of product ranges in bioresearch, consumer care, pharmaceutical & biotechnology, agro ingredients, industrial solutions, water treatment, and wood protection. It is segmented into pharmaceutical & biotechnology and specialty ingredients. In March 2009, the company joined the United Nations Global Compact as a strategic initiative to enhance its business. The company has worldwide operations across North America, Europe, Asia, France, and the UK.
PROMOCELL GMBH - PromoCell GmbH is a biotechnology company that offers a comprehensive portfolio of around 7,000 cell culture and cell biology products. Products of the company are used for diverse applications, such as cancer research, and immuno-oncology, diabetes, cardiovascular, & respiratory research. The company operates in more than 50 countries across different regions, including North America, Asia, and Europe.
CORNING INCORPORATED - Corning Incorporated is a publicly held company involved in delivering solutions for drug discovery and cell culture. This company has research centers located in North America, Europe, and Asia. It offers products for life sciences and pharmaceutical technologies. Its life sciences product portfolio covers bioprocess solutions, including single-use technology.
FUJIFILM IRVINE SCIENTIFIC - The company manufactures cell culture media, reagents, and medical devices for researchers, clinicians & scientists involved in cell therapy, regenerative medicine, cytogenetics, & reproductive technology. Irvine Scientific also provides industrial cell culture for large-scale production of biotherapeutics and vaccines. The company also offers consultative services to the customers, with expertise in cell culture and compliance.
MATTEK - Two professors from MIT founded Mattek, the company deals in the production of core polymer surface modification technology and 3D reconstruction of human tissue models into the emerging tissue engineering market. The company mainly focuses on producing human tissue models to replace animal testing. The various tissue models offered by the company are respiratory, ocular, skin, and intestinal tissue, which are used for assessing safety and efficacy in personal care, pharmaceutical, cosmetics, & household products industries. In addition, to its major offering, the company has expanded its product portfolio to include 3Diy kits, cultureware, primary cells & media, and testing services.
AXOL BIOSCIENCE LTD - Axol Bioscience Ltd. manufactures high-quality human cell products, media, and growth supplements. The company has expertise in reprogramming and differentiating cells into various cell types. The company provides customer cell services, stem cell reprogramming, genome editing, stem cell differentiation, and MEA screening services.
ATCC - ATCC is a nonprofit organization accredited by the American National Standards Institute (ANSI). It provides an extensive collection of products and services, including human & animal cell lines; primary, continuous, & immortalized stem cells; microbial derivatives; culture media; and reagents culture media. The biological materials developed by ATCC are often used as standards required by global regulatory agencies, such as the FDA, USDA, AOAC International, and Clinical Laboratory Standards Institute. It has official distributors in several countries, such as Brazil, Australia, Canada, China, South Korea, India, Israel, and Japan.
Supply Side Estimates
Company revenue estimation via referring to annual reports, investor presentations, and Hoover’s.
Segment revenue determination via variable analysis and penetration modeling.
Competitive benchmarking to identify market leaders and their collective revenue shares.
Forecasting via analyzing commercialization rates, pipelines, market initiatives, distribution networks, etc.
Demand side estimates
Identifying parent markets and ancillary markets
Segment penetration analysis to obtain pertinent
revenue/volume
Heuristic forecasting with the help of subject matter experts
Forecasting via variable analysis
Understanding market dynamics (in terms of drivers, restraints, & opportunities) in the countries.
Understanding trends & variables in the individual countries & their impact on growth and using analytical tools to provide high-level insights into the market dynamics and the associated growth pattern.
Understanding market estimates and forecasts (with the base year as 2022, historic information from 2018 to 2021, and forecast from 2023 to 2030). Regional estimates & forecasts for each category are available and are summed up to form the global market estimates.
The report provides market value for the base year 2022 and a yearly forecast till 2030 in terms of revenue/volume or both. The market for each of the segment outlooks has been provided on region & country basis for the above-mentioned forecast period.
The key industry dynamics, major technological trends, and application markets are evaluated to understand their impact on the demand for the forecast period. The growth rates were estimated using correlation, regression, and time-series analysis.
We have used the bottom-up approach for market sizing, analyzing key regional markets, dynamics, & trends for various products and end-users. The total market has been estimated by integrating the country markets.
All market estimates and forecasts have been validated through primary interviews with the key industry participants.
Inflation has not been accounted for to estimate and forecast the market.
Numbers may not add up due to rounding off.
Europe consists of EU-8, Central & Eastern Europe, along with the Commonwealth of Independent States (CIS).
Asia Pacific includes South Asia, East Asia, Southeast Asia, and Oceania (Australia & New Zealand).
Latin America includes Central American countries and the South American continent
Middle East includes Western Asia (as assigned by the UN Statistics Division) and the African continent.
GVR strives to procure the latest and unique information for reports directly from industry experts, which gives it a competitive edge. Quality is of utmost importance to us, therefore every year we focus on increasing our experts’ panel. Primary interviews are one of the critical steps in identifying recent market trends and scenarios. This process enables us to justify and validate our market estimates and forecasts to our clients. With more than 8,000 reports in our database, we have connected with some key opinion leaders across various domains, including healthcare, technology, consumer goods, and the chemical sector. Our process starts with identifying the right platform for a particular type of report, i.e., emails, LinkedIn, seminars, or telephonic conversation, as every report is unique and requires a differentiated approach.
We send out questionnaires to different experts from various regions/ countries, which is dependent on the following factors:
Report/Market scope: If the market study is global, we send questionnaires to industry experts across various regions, including North America, Europe, Asia Pacific, Latin America, and MEA.
Market Penetration: If the market is driven by technological advancements, population density, disease prevalence, or other factors, we identify experts and send out questionnaires based on region or country dominance.
The time to start receiving responses from industry experts varies based on how niche or well-penetrated the market is. Our reports include a detailed chapter on the KoL opinion section, which helps our clients understand the perspective of experts already in the market space.