The engineering and design of novel devices, systems, biologically based parts as well as the redesign of naturally existing biological systems is known as synthetic biology or engineering of biology. It is done to develop genetically modified organisms so that new preferred functions can be performed leading to increase in biological systems production. Synthetic biology is a new and revolutionary method of bioscience in which engineering principles are applied to biology in order to make new biological devices, systems, and parts. Recently synthetic biology has entered the commercial market and is passing through a nascent stage. Currently, there are consumer products in the market such as on department store shelves or grocery that contains the ingredients made by using advanced form of manufacturing and engineering. The original aim of synthetic biology was the production of biofuels and in the recent past, it has extended to industries such as scents, flavorings, cosmetics, and others.
There is also the usage of standard industrial fermentation and molecular biology for the production of sustainable, renewable algal oils that would pacify pressure that is there on the ecosystem due to habitat destruction and deforestation. The development of cheap synthesis procedures in life sciences is one of the most important roles of synthetic biology.DNA sequencing knowledge is built by synthetic biology and also there is an expectation of the development of bio-based chemicals, medicines, improvement of food crops, and sources of green energy. There are some potential environmental applications of synthetic biology such as bio-transformation, distinct chemicals immobilization, detection of environmental pathogens and contaminants, in situ biodegradation, and others that would attract the governments of various LDC’s and developing counties to invest on the same. The drivers for the market are molecular biology advancement, fall in the cost of data generation due to decreasing prices of DNA sequencing, increase in government funding and rise in demand of renewable energy such as biofuels, increasing demand of improved vaccines and drugs and rising demand for genetically modified crops due to the increasing population.
Key product segments of the synthetic biology market are core products and enabling products. Core product comprises synthetic genes, synthetic DNA, synthetic cells, chassis organisms, and XNA (xeno nucleic acid) whereas enabling product segment comprises oligonucleotide synthesis and DNA synthesis. Synthetic DNA has the largest market share as it has a high market penetration rate due to its extensive use in R&D and more commercialization than any other product segment.
Key application segments covered in this report are agriculture, chemicals (excluding biofuels), biofuels, and healthcare, others (R&D, biosecurity, energy, and environment). Healthcare covers the largest market share. Production of Artemisinin is considered to be one of the best health applications. Some of the potential applications of synthetic biology in health and food are regenerative medicine, reprogramming stem cells, new therapeutic methods, effective production of nutraceuticals for instance food supplements, vitamins, and preservatives. Biofuel is one of the most lucrative segments of the market.
Key technology segments of the synthetic biology market are DNA Sequencing, Genome Engineering, Biological Components and Integrated Systems, and Bioinformatics. Genome engineering has the largest market share followed by DNA sequencing and bioinformatics. The techniques and strategies developed for specific and targeted modification of genome or genetic are referred to as genome engineering.
Geographically, the global synthetic biology market is categorized into North America, Europe, Asia Pacific, and Rest of the World (RoW) regions. North America has the largest market share due to factors such as government assistance, funding, favorable regulations, and R&D in pharmaceuticals thus leading to the development of regenerative medicines and others. Europe is the fastest-growing market due to factors such as the increasing rate of GM crops and animals and biofuels in Western Europe for instance the U.K., France, and Germany. The U.K. is considered to be one of the most innovative and dynamic healthcare industries are expected to grow in the coming future.
Key players of this market include Amyris Inc. Agrivida, Inc. Algenol Biofuels, Inc., Bayer AG, ATG:biosynthetics GmbH, CBC Comprehensive Biomarker Center GmbH, Bioneer Corporation, Bristol-Myers Squibb, Biosearch Technologies, Inc., Gene Script Corporation, GeneWorks Pty Ltd., Ginkgo Bioworks, Exxon Mobil Corporation, Evolva SA, DuPont, Inc., Cobalt Technologies, New England Biolabs, Inc. and others.
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Biopharmaceutical innovators are at the forefront of the human response to the coronavirus pandemic. A significant number of major biotech firms are in the midst of a race to investigate the Sars-Cov-2 genome and prepare a viable vaccine for the same. As compared to the speed of response to SARS/MERs etc, the biotech entities are investigating SARs-Cov-2 at an unprecedented rate and a considerable amount of funds are being put into the R&D. With multiple candidates in trial, the public and private sectors are anticipated to work in unison for the foreseeable period, until a vaccine is developed for Covid-19. The report will account for Covid19 as a key market contributor.