The global animal model market size is estimated to reach USD 5.4 billion by 2033, registering a CAGR of 9.6% from 2026 to 2033, according to a new report by Grand View Research, Inc. Factors, such as the growing demand for precision medicine coupled with the rising implication of animal models owing to physiological similarities between humans and animals are driving the global market growth. In addition, advancements in animal-based models and rising implications of genetic engineering are propelling market expansion. The rising burden of life-threatening diseases like cancer, neurological disorders, cardiovascular disorders, and immunological disorders created an exponential demand for animal models.
These models help researchers in evaluating drug candidates, study disease progression, and allow testing therapeutic remedies prior they testing in human beings. Thus, the rising burden of chronic conditions has fueled the demand for animal-based models for research purposes. In addition, increasing efforts by pharmaceutical and biotechnology companies to develop novel therapeutics along with an increasing number of preclinical trials are projected to fuel the demand for various models like mice, guinea pigs, and others. Moreover, the introduction of CRISPR technology has revolutionized the field of genetics and biotechnology, while also allowing to create models with specific gene modifications to understand human diseases and develop newer treatments.
CRISPR technology offers a faster and more precise way to create animal models with specific genetic modifications. Using CRISPR, researchers can easily introduce, remove, or modify specific genes in the genome of an animal, allowing them to create animal models with precise genetic changes that are relevant to human diseases. For instance, in December 2022, Alberto Sols Biomedical Research Institute & Complutense University of Madrid utilized the CRISPR gene editing technique to incorporate a mutation into a mouse. The mutation carried the MCT8 protein, which is responsible for transporting thyroid hormones to the interior of human cells. The avatar mouse model will allow the researchers to curate a targeted therapy for Allan-Herndon-Dudley syndrome, a rare condition revealing an MCT8 mutation.
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By animal type, the mice segment accounting for the largest revenue share of 54.0% in 2025, and is expected to grow at the fastest CAGR from 2026 to 2033, driven by increasing investments and technological advancements in mouse model technology.
By application, the cancer segment dominated the market with a revenue share of 44.6% in 2025 and is expected to register the fastest growth rate over the forecast period, due to the exponential increase in the use of animal models in drug screening and preclinical testing to evaluate the efficacy and safety of anti-cancer therapeutics.
By end-use, the pharmaceutical & biotechnology companies segment accounting for the largest share of 39.2%, due to their dominant role in drug discovery, preclinical testing, and translational research activities.
North America dominated the global revenue share of 50.6% in 2025, driven by substantial investments in biomedical research, a strong presence of pharmaceutical and biotechnology companies, increasing preclinical R&D activities, and widespread adoption of advanced animal models for drug discovery and disease research.
Grand View Research has segmented the global animal model market based on animal type, application, end-use, and region:
Animal Model Animal Type Outlook (Revenue, USD Million/Billion, 2021 - 2033)
Mice
Rat
Guinea Pigs
Rabbits
Hamsters
Others
Animal Model Application Outlook (Revenue, USD Million/Billion, 2021 - 2033)
Cancer
Immunological Disease
Infectious Disease
Others
Animal Model End-use Outlook (Revenue, USD Million/Billion, 2021 - 2033)
Pharmaceutical & Biotechnology Companies
Academic Research Institute
Contract Research Organization
Animal Model Regional Outlook (Revenue, USD Million/Billion, 2021- 2033)
North America
U.S.
Canada
Mexico
Europe
Germany
UK
France
Italy
Spain
Denmark
Sweden
Norway
Asia Pacific
China
India
Japan
South Korea
Australia
Thailand
South Korea
Latin America
Brazil
Argentina
Middle East and Africa (MEA)
South Africa
Saudi Arabia
UAE
Kuwait
List of Key Players in the Animal Model Market
Charles River Laboratories
The Jackson Laboratory
genOway
Taconic Biosciences, Inc.
Janvier Labs
BioModels, LLC.
Crown Bioscience
Inotiv
BIOCYTOGEN
Hooke Laboratories
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