Animal Model Market Size, Share & Trends Analysis Report By Animal Type (Mice, Rat, Guinea Pig, Rabbit, Hamster, Monkey), By Technology, By Application, By End-user, By Region, And Segment Forecasts, 2023 To 2030

 Various forms of animal models such as mice, rats, zebrafish, dogs, and others replicate human anatomy to a certain extent. Moreover, the physiological or pathogenic response can be extrapolated by researchers using animal models. Animal models allow the researchers to perform various experiments, which in nature might be impractical or ethically outlawed in humans. Growing research and development activities by biopharmaceutical players, increasing traction towards drug discoveries, exponential increase in infectious and chronic diseases, and nuanced focus towards drug safety and efficacy propels the animal model market.

The growing investments within mouse model has induced strong growth for the market. For instance, in April 2022, the Medical Research Council or MRC announced the launch of National Mouse Genetics Network. The network is funded by MRCs USD 21 million investment over the period of five years. Cancer, degron tagging, haem, microbiome, MURIDAE, mitochondria, and congenital anomalies are the seven research clusters of the network.

The onset of COVID-19 pandemic positively impacted the market, as mice models were primarily used in vaccine and antiviral development. For instance, the K18-hACE2 transgenic mice model was recognized as a benchmark for immunogenicity and symptom replication of Sars-Cov-2 virus. Additionally, as per Journal of Virology 2022, K-18-hACE2 mice model has been the most sensitive COVID-19 model till date. Hence, replication of human-like-symptoms and understanding of disease prognosis will continue to aid the growth of animal model in clinical practices.

Investment in research and development activities by the governmental and private bodies are continually driving the animal model’s market. For instance, as per National Institutes of Health August 2022 article, almost all of USD 45 billion NIH budget is spent on medical research for the U.S. citizen. Furthermore, around 84% of the funding is awarded for extramural research via competitive grants and around 300,000 researchers and 2,500 universities, medical school, and various research institutions. Additionally, as per Oxford Academic 2018, nearly 60% of the extramural funding requires animal models, of which 80-90% are mouse models of human diseases. Owing to an easy access of research funds, various forms of drug research and pharmaceutical product development is necessitated.

Additionally, the introduction of CRISPR technology has revolutionized the field of genetics and biotechnology, while also allowing to create animal models with specific gene modifications to understand human diseases and develop newer treatments. CRISPR technology offers a faster and more precise way to create animal models with specific genetic modifications. Using CRISPR, researchers can easily introduce, remove, or modify specific genes in the genome of an animal, allowing them to create animal models with precise genetic changes that are relevant to human diseases. For instance, in December 2022, Alberto Sols Biomedical Research Institute & Complutense University of Madrid utilized CRISPR gene editing technique to incorporate a mutation into a mouse. The mutation carried MCT8 protein which is responsible for transporting thyroid hormones to the interior of human cells. The avatar mouse model will allow the researchers to curate a targeted therapy for Allan-Herndon-Dudley syndrome, a rare condition revealing MCT8 mutation. Thereby, introduction of CRISPR technology will help in curating more accurate and effective research on human diseases, proliferating the market of animal models.

The market of animal model is segmented based on animal type, technology, application, end-user, and region. The animal type segment includes mice, rate, guinea pigs, zebrafish, rabbits, hamsters, gerbils, monkeys, cattle, dogs, cats, and others. The technology segment is composed of CRISPR, microinjection, embryonic stem cell injection, nuclear transfer, and others. The application segment consists of research and development, production and quality control, academics, and others. The end-user segment is further divided into pharmaceutical & biopharmaceutical companies, contract research organizations, academic & research institutes, and others.

                                             Animal Model Market Segmentation

Animal models market incorporate various major companies. Some of the leading players operating in the market includes, Charles River Laboratories, The Jackson Laboratory, Inotiv, genOway, Taconic Biosciences, Inc., Janvier Labs, Harbour BioMed, Crown Bioscience, Horizon Discovery Ltd., and Trans Genic Inc.