Betulinic Acid Market Size To Reach $4,662.8 Million By 2033

Betulinic Acid Market Growth & Trends

The global betulinic acid market size is anticipated to reach USD 4,662.8 million by 2033, expanding at a CAGR of 7.3% from 2025 to 2033, according to a new report by Grand View Research, Inc. The industry is driven by its diverse applications across pharmaceuticals, cosmetics, and nutraceuticals. Betulinic acid, a naturally occurring pentacyclic triterpenoid primarily extracted from birch bark, has garnered attention for its anti-inflammatory, anti-cancer, anti-viral, and antioxidant properties. As consumer preference shifts towards natural and plant-based ingredients, betulinic acid's role in developing therapeutic and cosmetic products is expanding.

In the pharmaceutical sector, betulinic acid is being explored for its potential in treating various diseases, including cancer, HIV/AIDS, and neurodegenerative disorders. Its ability to inhibit the replication of viruses and its anti-cancer properties make it a valuable compound in drug development. The rising prevalence of chronic diseases and the demand for natural therapeutic agents are propelling research and investment in betulinic acid-based treatments.

The capsules segment is anticipated to grow fastest with a CAGR of 7.5% from 2025 to 2033 during the forecast period. The market is expected to grow due to its convenience, precise dosing, and ease of consumption for end-users. Capsules enhance the bioavailability and stability of betulinic acid, making them a preferred format in the nutraceutical and pharmaceutical industries. Their popularity is also driven by growing consumer preference for ready-to-use, supplement-based health products.

The pharmaceuticals segment dominated the market and accounted for the largest revenue share of 44.7% in 2024, due to its extensive use in developing drugs targeting cancer, viral infections, and inflammatory diseases.

North America accounted for the largest revenue share of 34.6% in 2024. The market is expected to grow due to high consumer awareness of natural and plant-based products, strong pharmaceutical and cosmetic industries, and robust R&D infrastructure. The region’s well-established healthcare sector and increasing adoption of nutraceuticals and functional ingredients further drive market growth.

Some of the prominent players in the global market include Manus Aktteva Biopharma LLP, Aktin Chemicals, Capot Chemicals, Kono Chem Co., Ltd., Tokyo Chemical Industry Co., Ltd., Glentham Life Sciences, Cayman Chemical, Jigs Chemical Limited, Toronto Research Chemicals (TRC), Xi’an Eco Biotech, Xi’an International Healthcare, DaXingAnLing Lingonberry Boreal Biotech Co., Ltd., and Symrise BioActives GmbH.

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Betulinic Acid Market Report Highlights

• Based on form, the powder segment accounted for the largest revenue share of 55.2% in 2024. This growth is due to its ease of handling, longer shelf life, and versatility in formulation across pharmaceuticals, nutraceuticals, and cosmetics.

• Asia Pacific is expected to grow at the fastest CAGR of 7.7% from 2025 to 2033. The growth is due to increasing consumer awareness of natural and plant-based ingredients, expanding pharmaceutical and nutraceutical industries, and rising disposable incomes. Countries like China and India are investing heavily in research and development for bioactive compounds, further driving market adoption.

• In January 2024, Betulin Lab achieved COSMOS Ecocert approval for birch bark extract production, allowing the sale of certified natural betulinic acid derivatives for premium cosmetics and skincare markets.

Betulinic Acid Market Segmentation

Grand View Research has segmented the global betulinic acid market on the basis of form, application, and region:

Betulinic Acid Form Outlook (Volume, Kilotons; Revenue, USD Million, 2018 - 2033)

• Powder

• Liquid

• Capsules

• Other Forms

Betulinic Acid Application Outlook (Volume, Kilotons; Revenue, USD Million, 2018 - 2033)

• Pharmaceuticals

• Cosmetics

• Nutraceuticals

• Other Applications

Betulinic Acid Region Outlook (Volume, Kilotons; Revenue, USD Million, 2018 - 2033)

• North America

  • U.S.

  • Canada

  • Mexico

• Europe

  • Germany

  • UK

  • France

  • Italy

  • Spain

• Asia Pacific

  • China

  • India

  • Japan

  • South Korea

• Latin America

  • Brazil

  • Argentina

• Middle East & Africa

  • Saudi Arabia

  • South Africa

List of Key Players in the Betulinic Acid Market

• Manus Aktteva Biopharma LLP

• Aktin Chemicals

• Capot Chemicals

• Kono Chem Co., Ltd.

• Tokyo Chemical Industry Co., Ltd.

• Glentham Life Sciences

• Cayman Chemical

• Jigs Chemical Limited

• Toronto Research Chemicals (TRC)

• Xi’an Eco Biotech

• Xi’an International Healthcare

• DaXingAnLing Lingonberry Boreal Biotech Co., Ltd.

• Symrise BioActives GmbH