Gene Synthesis (Research-use) Market To Reach $8.39 Billion By 2033

Gene Synthesis (Research Use) Market Growth & Trends

The global gene synthesis (research -use) market size is estimated to reach USD 8.39 billion by 2033, registering to grow at a CAGR of 16.8% from 2025 to 2033, according to a new report by Grand View Research, Inc. The market growth is primarily propelled by the growing number of research & development activities, increasing market competition, and the rising development in the field of synthetic biology. The wide range of applications associated with gene synthesis is also projected to drive the market growth. The methods involved in gene synthesis have unique advantages and make it feasible for widespread use. For instance, the solid-phase synthesis technique involved in gene synthesis allows for the acceleration of synthesis reaction by using solution-phase reagents in excess.

It can be conducted without the need for a purification process after each step. In addition, this method helps in improving the efficiency of the synthesis process. Thus, several companies, including Agilent Technology and Blue Heron Biotech, use solid-phase synthesis methods for gene synthesis. The market growth has been fueled significantly during the last few years owing to the growing interest in synthetic biology and gene synthesis research and development activities. In addition, established research institutions and universities that conduct research activities on synthetic biology and gene synthesis are expected to support the market growth. For instance, the Center for Synthetic Biology at the University of Copenhagen is one of the leading departments conducting research on synthetic biology in Denmark.

In addition, Integrated DNA Technologies (IDT), a major company in the gene synthesis market, introduced the Collab Network in February 2023, which unites industry partners and researchers for impactful research and technological development. These factors are expected to augment the growth in gene synthesis in the coming years. Furthermore, the growing industry competition strengthens gene synthesis services. Key companies implement various approaches to provide cost-effective services and bolster their position in the industry. These market players are focusing on upcoming opportunities in the market. For instance, a team of Evonetix, a company in gene synthesis, attended the Synthetic Biology: Engineering, Evolution & Design (SEED) 2023 conference in Los Angeles to understand the advances in synthetic biology, which can help them reinforce their position in the gene synthesis and synthetic biology industry.

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Gene Synthesis (Research-use) Market Report Highlights

• The solid-phase synthesis segment witnessed the highest revenue share in 2024 due to various benefits & advantages offered by this method and its high adoption by many players.

• The antibody DNA synthesis services segment held the largest revenue share in 2024 due to the high adoption of gene synthesis and its effectiveness in developing antibodies.

• The gene & cell therapy development application segment held the largest revenue share in 2024 and is expected to register the fastest CAGR over the forecast period. A rising number of gene & cell therapy development activities drives segment growth.

• The clinical research phase segment held the largest revenue share in 2024 and is expected to witness the fastest CAGR over the forecast period. Supportive government policies and the important role of gene synthesis in developing gene therapies are anticipated to drive the segment growth

• The academic & government research institutions end-use segment accounted for the largest share in 2024. The growing interest and emphasis on synthetic biology research are expected to propel the segment's growth.

• North America held the largest market share in 2024 due to the presence of various prominent players in the region. Asia Pacific is anticipated to register the fastest CAGR during the forecast period owing to the rising number of research activities for the development of therapeutics

Gene Synthesis (Research -use) Market Segmentation

Grand View Research has segmented the global gene synthesis (research-use) market based on method, service, application, research phase, end use, and region:

Gene Synthesis (Research-use) Method Outlook (Revenue, USD Million, 2021 - 2033)

• Solid-phase Synthesis

• Chip-based Synthesis

• PCR-based Enzyme Synthesis

Gene Synthesis (Research-use) Service Outlook (Revenue, USD Million, 2021 - 2033)

• Antibody DNA Synthesis
• Viral DNA Synthesis
• Others

Gene Synthesis (Research-use) Application Outlook (Revenue, USD Million, 2021 - 2033)

• Gene & Cell Therapy Development

• Vaccine Development

• Others

Gene Synthesis (Research-use) Research Phase Outlook (Revenue, USD Million, 2021 - 2033)

• Pre-clinical

• Clinical

Gene Synthesis (Research-use) End Use Outlook (Revenue, USD Million, 2021 - 2033)

• Biotechnology and pharmaceutical companies

• Academic and government research institutes

• Contract research organizations

Gene Synthesis (Research-use) Regional Outlook (Revenue, USD Million, 2021 - 2033)

• North America

  • U.S.

  • Canada

  • Mexico

• Europe

  • UK

  • Germany

  • France

  • Italy

  • Spain

  • Denmark

  • Sweden

  • Norway

• Asia Pacific

  • China

  • Japan

  • India

  • South Korea

  • Australia

  • Thailand

• Latin America

  • Brazil

  • Argentina

• Middle East & Africa

  • South Africa

  • Saudi Arabia

  • UAE

  • Kuwait

List of Key Players in Gene Synthesis (Research -use) Market

• GenScript

• Azenta, Inc. (GENEWIZ)

• Boster Biological Technology

• Twist Bioscience

• ProteoGenix

• Biomatik

• ProMab Biotechnologies, Inc.

• Thermo Fisher Scientific, Inc.

• Integrated DNA Technologies, Inc. (Danaher)

• OriGene Technologies, Inc.