The global in-vitro toxicology testing market size is anticipated to reach USD 30.9 billion by 2027 and is projected to register a CAGR of 9.2% over the forecast period, according to a new report by Grand View Research, Inc. The new paradigm shift in toxicity testing of animal models toward computational methods such as silico models to interpret toxicity pathway data, drives the demand for in-vitro toxicology testing. These methods provide cost and time efficiency and enhance safety assessment.
Several governments are taking measures to minimize animal-based test models, forming conducive government policies, and providing funds to support in-vitro models. These factors are expected to create ample growth opportunities for the market. For instance, in November 2019, the U.S. National Institute for Environmental Health Sciences planned to provide funds to small companies for the development of engineered 3D culture or organotypic culture models (OCM) in-vitro systems.
With advancements in high throughput screening, biological screening, and chemical synthesis, the number of publicly available databases containing data related to toxicity; absorption, distribution, metabolism, and excretion (ADME); pharmacovigilance; and drug screening has expanded rapidly. This has enabled scientists to access vast information for toxicity profiling, thereby spurring revenue generation in this market.
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Further key findings from the report suggest:
Growing application of 3D-spheroid-cultures, particularly for nanoparticle toxicity testing, resulted in the dominance of the cell culture technology segment in 2019
Omics technology is anticipated to register lucrative growth as RNA sequencing and shotgun proteomics are increasingly used for a more comprehensive understanding of the effects of toxicants
The high usage rate of cellular assays with advancements in cell-based technologies, including label-free detection and high-content screening, has contributed to the dominance of the cellular assays segment in 2019
Systemic toxicology emerged as the leading application segment in 2019 as it plays a key role in risk assessment during drug development procedures. For instance, toxicity testing of systemic immunosuppressive drugs and systemic corticosteroids is important during the development of drugs for ocular inflammatory disease
Pharmaceutical industry dominated the in-vitro toxicology testing market in 2019 as toxicological testing is a prerequisite step for drug development
Stringent government regulations regarding animal usage for toxicity analysis in North America have led to an increased adoption rate of in-vitro models. Hence, North America dominated the global market in 2019
The Asia Pacific region is anticipated to witness the fastest growth rate over the forecast period due to increasing initiatives by public agencies to encourage acceptance of non-animal test models
Abbott, Thermo Fisher, Agilent Technologies, GE Healthcare, Bio-Rad, and Merck KGaA are some of the key players operating in the market.
Grand View Research has segmented the global in-vitro toxicology testing market on the basis of technology, method, application, end use, and region:
In-vitro Toxicology Testing Technology Outlook (Revenue, USD Million, 2016 - 2027)
Cell Culture Technology
High Throughput Technology
In-vitro Toxicology Testing Method Outlook (Revenue, USD Million, 2016 - 2027)
In-vitro Toxicology Testing Application Outlook (Revenue, USD Million, 2016 - 2027)
In-vitro Toxicology Testing End-use Outlook (Revenue, USD Million, 2016 - 2027)
Cosmetics & Household Products
In-vitro Toxicology Testing Regional Outlook (Revenue, USD Million, 2016 - 2027)
Middle East and Africa (MEA)
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