The global qPCR instruments market size is expected to reach USD 2.02 billion by 2033, registering a CAGR of 7.0% from 2026 to 2033, according to a new report by Grand View Research, Inc. The market is driven by the introduction of novel advanced products and an increase in demand for highly efficient diagnostic equipment.
The demand for qPCR instruments and consumables is being driven by the spike in the incidence of SARS-CoV-2 infections globally. The rise in the incidence is expected to add to the number of preventive screenings. This can be attributed to the fact that nations cannot determine the number of COVID-19 patients without screening them.
The miniaturization of three basic molecular assays is expected to increase the accuracy and specificity of diagnostic outcomes, and hence, increase the demand for molecular diagnostic products. These improvements are expected to improve the availability of POC molecular diagnostic tests to yield quick and effective test results. For instance, the Mic qPCR system by Biomolecular Systems weighs only 2 kilograms, making the device highly portable and easy to handle.
Newly launched products such as QuantStudio 5 Dx Real-Time PCR System provide consumers with improved workflows and high-volume testing to provide faster results. Cost-effectiveness and software that are simplified give it additional advantages. Furthermore, the approval of the instrument in over 50 countries can help strengthen the market growth. The instrument is also equipped with measures for research companion diagnostics, giving it a competitive edge.
The market has a high threat of external substitutes owing to the presence of digital PCR instruments that are highly advanced and more accurate. The strong threat of internal substitution can be attributed to the presence of numerous products available in the market. However, the higher price of these instruments is anticipated to reduce the overall threat, keeping it at a moderate level.
COVID-19 has increased opportunities for diagnostic devices. However, advanced PCR technologies, such as dPCR, are preferred more in developed economies as they can help reduce false-positive rates. The research on developing efficient qPCR instruments can reduce the threat of substitution of devices and improve market growth.
Over recent years, PCR has witnessed technological advancements in terms of sensitivity, accuracy, efficiency, and cost-effectiveness. Key players are introducing novel technologies to maintain a competitive edge.
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QuantStudio segment accounted for the largest market share of 20.98% in 2025. The segment is anticipated to maintain its leading position over the forecast period due to its widespread adoption in clinical diagnostics and research laboratories, high sensitivity and reproducibility, compatibility with a broad range of assays, and increasing demand for reliable, high throughput real time PCR systems in infectious disease testing, genomics, and applied research applications.
Standalone qPCR instruments segment accounted for the largest market share of 57.49% in 2025 and is expected to grow at the fastest CAGR over the forecast period.
North America qPCR instruments market accounted for the largest revenue share of 40.95% in 2025 and is expanding at a CAGR of 6.8% due to rising demand for rapid, accurate molecular diagnostics across the United States, Canada, and Mexico, especially for respiratory infections, pandemic preparedness, and population surveillance.
Grand View Research has segmented the qPCR Instruments Market on the basis of instruments, type, and region:
qPCR Instruments Instruments Outlook (Revenue, USD Million, 2021 - 2033)
7500
QuantStudio
StepOne/StepOne Plus
LightCycler
Cobas 4800/5800/6800/8800
GeneXpert
Rotor-Gene Q
BioFire FilmArray Systems
BMS Mic System
Cobas Z480
CFX
Others
qPCR Instruments Type Outlook (Revenue, USD Million, 2021 - 2033)
Standalone qPCR Instruments
Integrated/Automated Molecular Systems
qPCR Instruments Regional Outlook (Revenue, USD Million, 2021 - 2033)
North America
U.S.
Canada
Mexico
Europe
UK
Germany
France
Italy
Spain
Denmark
Sweden
Norway
Asia Pacific
Japan
China
India
Australia
South Korea
Latin America
Brazil
Argentina
Middle East & Africa
South Africa
Saudi Arabia
UAE
Kuwait
List of Key Players in the qPCR Instruments Market
Thermo Fisher Scientific, Inc.
F. Hoffmann-La Roche Ltd.
Bio-Rad Laboratories, Inc
Danaher Corporation
Qiagen
Agilent Technologies, Inc.
Abbott
bioMérieux SA
Quantabio
Azure Biosystems, Inc.
Bio Molecular Systems
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