North America Microbiome Sample Preparation Technology Market To Reach $152.1 Million By 2030

North America Microbiome Sample Preparation Technology Market Growth & Trends

The North America microbiome sample preparation technology market size is expected to reach USD 152.1 Million by 2030 and is anticipated to grow at a CAGR of 6.1% from 2025 to 2030. The increasing adoption of precision medicine across clinical and research settings accelerates the demand for microbiome-based insights. Healthcare providers and researchers use microbiome data to design targeted therapies, particularly for chronic illnesses and metabolic disorders. This trend toward personalized treatment strategies boosts the need for accurate and efficient sample preparation technologies. High-throughput sequencing workflows depend on precise sample handling to maintain data integrity, driving the uptake of advanced preparation kits and automation tools. A strong focus on reproducibility and quality in scientific research further amplifies the demand for standardized processing methods. As a result, sample preparation technologies are becoming essential to the growing microbiome research ecosystem.

Another significant driver is the expanding application of microbiome studies in the pharmaceutical and biotechnology sectors. Companies are investing in microbiome-based drug development, focusing on therapies for gastrointestinal, neurological, and autoimmune conditions. To support these efforts, firms require scalable and consistent sample preparation platforms to handle large volumes of complex biological specimens. The rise in clinical trials involving microbiome interventions intensifies the need for robust technologies that minimize variability and contamination. Additionally, partnerships between research institutes and industry players accelerate innovation in preparation tools and protocols. These collaborations are enhancing the overall efficiency and accuracy of microbiome analysis workflows.

Technological advancements in automation and workflow integration are further contributing to market expansion. Laboratories are moving toward fully integrated systems that combine extraction, purification, and quality control in a single platform. These solutions save time, reduce manual errors, and improve throughput, making them highly attractive to academic and commercial labs. As data complexity increases, there is a growing requirement for software and instruments that ensure consistency from sample to sequencing. The emergence of user-friendly, high-performance systems is supporting wider adoption among non-specialist users. This trend enables more institutions to conduct in-house microbiome research, driving sustained demand for sample preparation technologies across North America.

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North America Microbiome Sample Preparation Technology Market Report Highlights

• Based on product, the consumables segment is expected to witness the fastest growth at a CAGR of 6.23% during the forecast period. This is due to the increasing demand for high-throughput and accurate microbiome analysis. Expansion of laboratory networks across the U.S. and Canada has further supported the rising consumption of single-use preparation products.

• Based on workflow, the sample extraction/isolation segment dominated the market and accounted for the largest revenue share of 21.7% in 2024, driven by the critical need for high-quality microbial DNA and RNA in downstream applications. Strong presence of key players offering advanced extraction tools has reinforced segment leadership in the region.

• Based on application, the DNA sequencing segment dominated the market and accounted for the largest revenue share in 2024, driven by the rapid adoption of next-generation sequencing platforms in microbiome research.

• Based on disease, the gastrointestinal disorders segment dominated the market. It accounted for the largest revenue share in 2024, driven by the growing recognition of the gut microbiome's role in chronic disease progression. In North America, healthcare providers and research institutes invest heavily in understanding gut microbial imbalance.

• Based on end use, the diagnostic labs segment held the largest revenue share in 2024, driven by the expansion of clinical microbiome testing services across North America. Demand for accurate microbial profiling in disease diagnosis has prompted labs to adopt specialized sample preparation technologies. 

North America Microbiome Sample Preparation Technology Market Segmentation

Grand View Research has segmented the North America microbiome sample preparation technology market based on product, workflow, application, disease, end use, and region:

North America Microbiome Sample Preparation Technology Product Outlook (Revenue, USD Million, 2018 - 2030)

• Consumables

  • Purification/Extraction Kits

  • Library prep kits

    • DNA Library Preparation Kits

    • RNA Library Preparation Kits

    • Library Quantitation & Amplification kits

    • Clean-up and Selection Kits

    • Microbiome DNA Enrichment

    • Others

• Instruments

  • Workstation

  • Extraction System

  • Liquid Handling Instrument

  • Other Sample Preparation Instruments

North America Microbiome Sample Preparation Technology Workflow Outlook (Revenue, USD Million, 2018 - 2030)

• Sample Extraction/Isolation

• Library Preparation

• Sample Quantification

• Fragmentation

• Target Enrichment

• Quality Control

• Pooling

• Library Quantification

North America Microbiome Sample Preparation Technology Application Outlook (Revenue, USD Million, 2018 - 2030)

• DNA Sequencing

• RNA Sequencing

• Methylation Sequencing

• Single Cell Sequencing

• Whole-Genome Sequencing

• Metagenomics

• Others

North America Microbiome Sample Preparation Technology Disease Outlook (Revenue, USD Million, 2018 - 2030)

• Gastrointestinal Disorders

• Autoimmune Disorder

• Cancer

• Others

North America Microbiome Sample Preparation Technology End Use Outlook (Revenue, USD Million, 2018 - 2030)

• Diagnostic Labs

• Pharmaceutical & Biotechnology

• Others

North America Microbiome Sample Preparation Technology Country Outlook (Revenue, USD Million, 2018 - 2030)

• U.S.

• Canada

• Mexico

List of Key Players in North America Microbiome Sample Preparation Technology Market

• QIAGEN

• BGI

• Bio-Rad Laboratories, Inc.

• Perkin Elmer, Inc.

• Agilent Technologies Inc.

• Illumina, Inc.

• F. Hoffmann-La Roche Ltd.

• Danaher Corporation