The global adaptive optics market size was valued at USD 236.0 million in 2019 and is expected to grow at a compound annual growth rate (CAGR) of 9.0% from 2020 to 2027. Adaptive Optics (AO) is rapidly gaining demand as an option for improving the performance of optical systems. Optical instruments experience inaccuracies while measuring and imaging due to distortions seen in light waves. Adaptive optics helps in negating these inaccuracies, thereby, enhancing the performance of the optical instruments. The growing prevalence of retinal degeneration diseases is expected to propel the growth of the market. Age-related Macular Degeneration (AMD) and Retinitis Pigmentosa (RP) are the most common retinal degenerative diseases globally. As per Nano Retina, by 2014, around 170.0 million people were living with AMD and 1.5 million with RP worldwide. The number of people with AMD is estimated to increase to 196.0 million by the end of 2020 and 288.0 million by 2040. An adaptive optics fundus camera helps in observing the disruptions in the cone mosaic of a patient with RP.
High-resolution phenotyping with adaptive optics imaging along with molecular genetic analyses is expected to enhance the clinical imaging of AMD and RP in the early stages. The growing usage of adaptive optics for clinical application and research is expected to boost the overall market growth. Adaptive optics along with Optical Coherence Tomography (OCT) is gradually penetrating the market due to its effectiveness in providing improved and high-speed imaging. Advanced deformable mirrors are being developed to precisely control the incident wavefront by reshaping a reflecting membrane with the help of accurate magnetic actuators.
The development of these deformable mirrors is expected to reduce the size, cost, and complexity of AO-OCT devices, thereby, making adaptive optics widely accepted for various clinical applications. Therefore, the development of advanced adaptive optics devices along with the growing efforts of vision scientists, ophthalmologists, and entrepreneurs in its development and research, is expected to drive the market.
Despite the advantages of adaptive optics in various clinical applications and research, there are certain established drawbacks of AO. The algorithm for image acquisition, processing, and montaging, patient fixation problems, and lengthy analyses are some of the major challenges associated with adaptive optics. Additionally, the high cost of these adaptive optics products is also expected to slow the adoption of these devices in a clinical office setting, especially in developing countries.
Wavefront sensors held the largest revenue share of 36.2% in 2019. The sensor helps in splitting the light into small beams with the help of an array of miniature lenses, termed lenslets. The most commonly used sensor is the Shack-Hartmann Wavefront Sensor due to its simple structure and easy manufacturability. Other techniques that are used for wavefront sensing are curvature and pyramid sensors, however, usage of these sensors is comparatively low considering their complexity.
Additionally, the associated advantages of wavefront sensors over topography are also expected to boost segment growth. The major advantage which wavefront sensors possess over corneal topographers is that the topographer only tells about the surface of the optics of the eye. However, the wavefront sensors give an idea about the complete effect of all the optical surfaces. This, in turn, helps in enhancing the quality of the retinal image.
Deformable Mirrors (DM) is expected to grow at the fastest rate of 9.2% during the forecast period. Wavefront correctors are the most adaptive element in AO and deformable mirrors are used for this function. These mirrors are thin and flexible reflective layers, whose structure or shape is controlled by a variety of mechanisms. Based on the application, DM is selected. They come with advanced specifications like actuator count, speed, stoke, inter-actuator coupling, and surface finish. These specifications of DM differ based on the application for which they are being used. Therefore, players are focusing on developing specific DM for different applications to enter the market or to sustain in the market, thereby, positively impacting the overall market growth.
Microscopy held the largest revenue share of 33.5% in 2019. In-vivo imaging is critical in biological microscopy since for studying cellular processes, living tissues act as an important part. The major challenge faced while studying the living tissue is the amount of light, as it can damage the sample and may not provide an illuminated structure. Therefore, adaptive optics is widely used in microscopy to overcome these challenges. AO helps in increasing the resolution, signal strength, and contrast ratio. These advantages of AO aid in in-vivo deep-tissue imaging.
Additionally, adaptive optics helps in resolving the issue faced while using high-power microscopes for researching a large sample. Adaptive optics patch the image together of a large sample as a mosaic by using its fast scanning microscope stage property. Moreover, it also helps in compensating aberrations caused due to optical imperfections. Therefore, the effectiveness of AO in medical microscopy and the availability of these devices at low cost in comparison to a high-powered, wide field of view scanning microscope, is expected to drive the segment growth.
The ophthalmology segment is expected to grow at the fastest rate during the forecast period. The adaptive optics non-invasively help in detecting, diagnosing, and treating eye diseases. The growing adoption of adaptive optics for retinal imaging is expected to fuel the segment growth. Conventional optical imaging devices are facing challenges in diagnosing retinal diseases due to the eye’s monochromatic aberrations which occur because of the imperfections in the optics of the eye. Adaptive optics is used to measure and correct these aberrations for providing a limited diffracted image. Therefore, owing to the effectiveness of AO it comes in various forms like AO fundus camera, AO scanning laser ophthalmoscope, and AO-OCT in the field of ophthalmology, thereby, expected to propel the segment growth.
North America held the largest revenue share of 26.3% in 2019 in the adaptive optics market. The use of advanced technologies in the biomedical sector by countries like the U.S. and Canada is expected to propel market growth in the region. Additionally, the growing research regarding adaptive optics in various institutions and research centers present in the region is also expected to drive market growth. For instance, the Medical College of Wisconsin is researching adaptive optics under its Advanced Ocular Imaging Program (AOIP). Under this program, several volunteers have participated to share their insights and understand the effective AO in treating retinal disease. For conducting research under AOIP, two AO scanning light ophthalmoscope systems by Dubra lab have been used. These systems come along with several associated advantages regarding the gathering of data on photoreceptors, nerve fiber layers, and vasculature of the retina.
In Europe, the market is expected to experience significant growth during the forecast period. Gradual adoption and development of adaptive optics devices for usage in the biomedical field are expected to propel market growth in Europe. Imagine Eyes, a company based in France, has come up with an adaptive optics retinal camera, rtx1 for examining the retina in a more precise manner. This product by the company is frequently used for research purposes. In July 2020, the professors and researchers used rtx 1 to understand the effect of cardiometabolic conditions on the retina. A recent study published by Clinical Research in Cardiology examined the retinas of 429 volunteers with different cardiometabolic problems using the rtx 1 AO retinal camera.
In Asia Pacific, the market is expected to experience the fastest growth rate during the forecast period. The growing market clearance of adaptive optics devices in countries like China, Japan, India, and South Korea is expected to boost the market growth in the APAC region. In March 2020, Imagine Eye’s AO retinal camera, rtx 1 received regulatory clearance in China. Additionally, Imagine Eyes entered into a partnership with Aracare for increasing the distribution of its product rtx 1 in South Korea.
The key market players form strategic alliances such as partnerships, distribution agreements, M&As for developing adaptive optics devices and to increase the reach of these devices. For instance, in March 2017, Imagine Eye signed a distribution agreement with Chuo Sangio Co. for selling rtx1-e Adaptive Optics Retinal Camera in Japan. Some of the prominent players in the adaptive optics market include:
IMAGINE OPTIC SA
Northrop Grumman Corporation
Iris AO, Inc.
Boston Micromachines Corporation
Market size value in 2020
USD 252.9 million
Revenue forecast in 2027
USD 463.2 million
CAGR of 9.0% from 2020 to 2027
Base year for estimation
2016 - 2018
2020 - 2027
Revenue in USD million and CAGR from 2020 to 2027
Revenue forecast, company share, competitive landscape, growth factors, and trends
Component, application, regional
North America; Europe; Asia Pacific; Latin America; Middle East & Africa
U.S.; Canada; U.K.; Germany; France; Italy; Spain; China; India; Japan; Thailand; South Korea; Mexico; Brazil; Colombia; Argentina; South Africa; Saudi Arabia; UAE
Key companies profiled
IMAGINE OPTIC SA; Northrop Grumman Corporation; Iris AO, Inc.; Adaptica; Boston Micromachines Corporation; Imagine Eyes; ALPAO
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This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2016 to 2027. For the purpose of this study, Grand View Research has segmented the global adaptive optics market report on the basis of component, application, and region:
Component Outlook (Volume, Units; Revenue, USD Million, 2016 - 2027)
Deformable Mirrors (Wavefront Correctors)
Application Outlook (Revenue, USD Million, 2016 - 2027)
Regional Outlook (Volume, Units; Revenue, USD Million, 2016 - 2027)
Middle East & Africa
b. The global adaptive optics market size was estimated at USD 236.0 million in 2019 and is expected to reach USD 252.9 million in 2020.
b. The global adaptive optics market is expected to grow at a compound annual growth rate of 9.0% from 2020 to 2027 to reach USD 463.2 million by 2027.
b. North America dominated the adaptive optics market with a share of 26.3% in 2019. This is attributable to the adoption of advanced technologies in biomedical by countries like the U.S. and Canada and the growing research regarding adaptive optics in various institutions and research centers present in the region.
b. Some key players operating in the adaptive optics market include AKA Optics SAS, Teledyne e2v (UK) Ltd, Thorlabs, Inc., IMAGINE OPTIC SA, Northrop Grumman Corporation, Iris AO, Inc., Adaptica, Boston Micromachines Corporation, Imagine Eyes, and ALPAO.
b. Key factors that are driving the adaptive optics market growth include the increasing prevalence of retinal diseases, growing adoption of the non-invasive procedure, and a growing number of clinical trial studies for adaptive optics.
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