Blood Group Typing Market (2026 - 2033)

Blood Group Typing Market Summary

The global blood group typing market size was valued at USD 2.3 billion in 2025 and is projected to grow from USD 2.5 billion in 2026 to USD 5.6 billion by 2033, at a CAGR of 12.0% from 2026 to 2033. North America dominated the market, accounting for a revenue share of 44.9% in 2025. Market growth is driven by the rising burden of chronic diseases such as anemia, cancer, and blood disorders, which increases the need for frequent transfusions.

In addition, the growing number of surgical procedures, organ transplants, and trauma cases is further driving demand for accurate blood compatibility testing. The high burden of chronic diseases such as anemia, cancer, and hematological disorders is a significant driver of the blood group typing market, as these conditions often require frequent blood transfusions. For instance, according to a World Health Organization report published in 2025, anemia affects nearly 30% of women of reproductive age and around 40% of children under five globally, highlighting a substantial patient pool requiring transfusion support. Similarly, increasing cancer incidence and blood disorders such as thalassemia and sickle cell disease are contributing to repeated transfusion needs. This growing transfusion volume necessitates accurate ABO and Rh typing to ensure compatibility and prevent adverse reactions. Consequently, the rising prevalence of these chronic conditions is significantly accelerating demand for advanced blood group typing solutions worldwide.

The growing number of surgical procedures, organ transplants, and trauma cases is driving the demand for accurate blood compatibility testing, thereby supporting the growth of the blood group typing market. For instance, according to the World Health Organization (December 2023), around 1.2 million people die each year due to road traffic accidents, while many sustain non-fatal injuries and many require emergency transfusions. In addition, the number of organ transplant procedures has increased globally. According to an article published in PubMed in 2026, 173,727 solid organ transplants were performed worldwide in 2024, and these statistics were reported by the Global Observatory on Donation and Transplantation, an initiative of the WHO. These clinical situations require precise ABO and Rh typing and cross-matching to ensure patient safety. As the volume of surgeries and emergency care continues to rise, the need for reliable blood group typing solutions is also increasing.

Expanding blood donation programs and increasing transfusion volumes are contributing to the demand for routine blood group typing and compatibility testing. For instance, according to the statistics published by the World Health Organization in May 2025, over 118.5 million blood donations are collected globally each year, all of which require mandatory blood grouping and screening before use. In addition, advancements in molecular and automated typing technologies, including PCR-based genotyping, are improving accuracy and reducing turnaround time. The growing use of blood group typing in prenatal testing for diagnosing hemolytic disease of the newborn (HDN), along with stricter regulatory standards for transfusion safety, is further supporting the adoption of advanced typing solutions, thereby supporting overall market expansion. However, stringent approval processes and varying regulatory frameworks across regions can delay product launches and market entry.

Market Dynamics

Market Concentration & Characteristics

The blood group typing market is experiencing a high degree of innovation, driven by rapid technological advancements and evolving clinical requirements. There is a clear shift toward molecular and genotyping techniques, including PCR and next-generation sequencing (NGS), enabling the precise identification of rare blood antigens and improving transfusion safety. Automation and artificial intelligence are increasingly being integrated into laboratory workflows to enhance efficiency, reduce manual errors, and support complex data interpretation. In addition, the development of lab-on-a-chip and point-of-care devices is enabling rapid blood typing in emergency settings. For instance, in May 2024, Thermo Fisher Scientific launched the Applied Biosystems Axiom BloodGenomiX Array and Reporter Software, a high-throughput solution for blood group genotyping. The platform detects over 260 antigens across 38 blood group systems in a single assay. This DNA-based approach enables identification of rare blood groups with high accuracy and integrates automated analysis to improve workflow efficiency and transfusion safety.

The blood group typing industry is witnessing a moderate to high level of M&A activity, driven by the need to expand technological capabilities and strengthen product portfolios. Leading players are actively engaging in strategic deals to integrate molecular diagnostics and automation into transfusion medicine. For instance, in January 2025, Haemonetics Corporation agreed to sell its whole blood assets to GVS S.p.A for USD 67.1 million, including an upfront payment of USD 44.6 million and up to USD 22.5 million in contingent earn-outs. The deal includes the transfer of its whole blood collection, processing, and filtration portfolio, along with its manufacturing facility in Covina, California.

Regulations significantly influence the blood group typing market by ensuring safety, quality, and standardization in transfusion practices. For instance, according to the World Health Organization, blood and blood components are regulated as essential biological products requiring strict quality control. Mandatory screening of donated blood for infectious diseases such as HIV and hepatitis further drives the need for accurate typing and compatibility testing. In countries such as India, regulatory bodies mandate licensing and adherence to national standards for blood banks. While these regulations enhance patient safety and reduce transfusion risks, they also increase compliance costs and operational complexity for laboratories and healthcare providers.

The blood group typing market is expanding across regions, supported by improving healthcare infrastructure and increasing access to diagnostic services in emerging economies. Countries in Asia Pacific, Latin America, and the Middle East are witnessing higher investments in blood banks, transfusion services, and laboratory capabilities. For instance, government initiatives in countries such as India and China are strengthening blood donation systems and expanding diagnostic networks, increasing the demand for blood typing solutions. In addition, market players are focusing on expanding their presence through partnerships, distribution agreements, and participation in international healthcare events. This regional expansion is improving accessibility to advanced blood typing technologies and supporting overall market growth.

Product Insights

The reagents & consumables segment dominated the market, with the largest revenue share of 71.49% in 2025, driven by recurring demand for routine blood typing and compatibility testing across blood banks and diagnostic laboratories. For instance, in March 2025, Grifols S.A. partnered with Inpeco to enhance automated transfusion workflows, which rely heavily on a steady supply of reagents and consumables for high-throughput testing. This reflects the recurring consumption pattern for these products, supporting sustained dominance in the segment. In addition, increasing blood donation volumes and rising adoption of automated systems are further driving the demand for consumables, reinforcing the segment’s leading position in the market.

Services segment is projected to grow at the fastest CAGR over the forecast period, fueled by increasing outsourcing of blood typing, testing, and laboratory management services, along with rising demand for specialized diagnostic support. For instance, in May 2024, Thermo Fisher Scientific collaborated with New York Blood Center Enterprises to co-develop advanced blood genotyping solutions, along with integrated data analysis and support services. This reflects the growing demand for integrated service offerings, including software, analytics, and technical support, thereby contributing to the expansion of the services segment.

Techniques Insights

PCR-based and Microarray-based segment dominated the market with the largest revenue share of 52.04% in 2025 due to their high accuracy, sensitivity, and ability to detect rare and complex blood group antigens. These methods enable extended antigen profiling beyond conventional serological techniques, improving transfusion safety. For instance, in May 2024, Thermo Fisher Scientific launched the Applied Biosystems Axiom BloodGenomiX Array, a microarray-based platform that enables high-throughput genotyping of over 260 antigens across multiple blood group systems. This highlights the increasing adoption of advanced molecular techniques, supporting segment growth.

Assay-based techniques segment is anticipated to witness strong growth over the forecast period due to increasing adoption of automated and standardized testing methods for routine blood grouping and antibody screening. These techniques offer faster turnaround time, ease of use, and cost-effectiveness compared to advanced molecular methods, making them suitable for high-volume laboratories and blood banks. Additionally, rising demand for reliable serological testing in emergency and point-of-care settings is supporting segment growth. Continuous advancements in gel card and solid-phase assays, along with increasing blood donation and transfusion activities, are further contributing to the expansion of this segment.

Test Type Insights

The antibody screening segment dominated the market accounting for 38.91% revenue share in 2025, due to its essential role in detecting unexpected antibodies that may lead to transfusion reactions. This test is routinely performed before blood transfusions, surgeries, and during pregnancy to ensure compatibility and patient safety. For instance, in April 2026, advanced automated blood screening systems were introduced at AIIMS Mangalagiri to enhance detection accuracy and reduce turnaround time. Additionally, increasing adoption of automated immunohematology analyzers, rising transfusion volumes, and growing focus on transfusion safety are further contributing to the sustained growth of the antibody screening segment.

The HLA typing segment is projected to grow at a CAGR of 13.8% over the forecast period, driven by the increasing number of organ and stem cell transplants, which require precise human leukocyte antigen matching to prevent rejection. Rising awareness of transplant compatibility and advancements in molecular typing techniques, including PCR and next-generation sequencing, are improving accuracy and outcomes. Additionally, growing adoption of HLA typing in disease association studies and personalized medicine is supporting segment growth. Increasing investments in transplant infrastructure and expanding donor registries globally are further contributing to the rising demand for HLA typing services.

Regional Insights

North America blood group typing market dominated the global market and accounted for 44.85% share in 2025 due to advanced healthcare infrastructure, high adoption of automated and molecular diagnostics, and strong regulatory frameworks. The region benefits from a well-established network of blood banks and high awareness of transfusion safety. The increasing prevalence of chronic diseases, such as cancer and blood disorders, continues to drive transfusion demand. Additionally, technological advancements, including molecular typing and automation, are widely adopted across laboratories. The presence of key players such as Thermo Fisher Scientific and Bio-Rad Laboratories further supports market growth. Favorable reimbursement policies and continuous investments in healthcare innovation also contribute to sustained demand for advanced blood typing solutions.

U.S. Blood Group Typing Market Trends

The blood group typing industry in the U.S. represents the largest share in North America, driven by high healthcare spending and strong regulatory oversight. The country performs a large number of surgeries, transplants, and transfusions annually, increasing the demand for accurate blood typing. According to the American Red Cross, millions of blood units are collected each year, all of which require mandatory typing and screening. The U.S. also leads in adopting molecular typing and automation technologies. Additionally, the presence of advanced research institutions and diagnostic companies supports continuous innovation in transfusion medicine, further strengthening the market landscape.

Europe Blood Group Typing Market Trends

Europe represents a mature blood group typing industry characterized by strong regulatory standards and widespread adoption of advanced transfusion practices. Countries across the region emphasize blood safety and quality, supported by well-established healthcare systems and national blood services. Increasing demand for blood due to aging populations and rising chronic disease prevalence is contributing to market growth. The adoption of automated analyzers and molecular typing methods is increasing across laboratories. Regional organizations such as the European Blood Alliance promote best practices in blood transfusion and donor management, further supporting market expansion. Continuous focus on research and innovation also enhances the adoption of advanced blood typing technologies.

The blood group typing market in UK is supported by a centralized and highly regulated healthcare system. The NHS Blood and Transplant plays a key role in managing blood donation, testing, and distribution across the country. Increasing demand for transfusions due to surgeries, cancer treatments, and chronic diseases is driving the need for accurate blood typing. The UK is also adopting advanced technologies, including automated systems and molecular typing, to improve efficiency and safety. Strong regulatory oversight ensures adherence to high-quality standards, while ongoing investments in healthcare infrastructure support the adoption of innovative diagnostic solutions.

The blood group typing market in Germany is growing over the forecast period, driven by advanced healthcare infrastructure and strong emphasis on diagnostic quality. The country has a well-developed network of hospitals and blood banks, supporting high volumes of blood collection and transfusion. Increasing adoption of automated and molecular blood typing technologies is enhancing diagnostic accuracy and efficiency. Germany also benefits from strong regulatory compliance and healthcare funding. Organizations such as the German Red Cross play a significant role in blood collection and transfusion services. The presence of established diagnostic companies further contributes to technological advancements and market growth.

Asia Pacific Blood Group Typing Market Trends

Asia Pacific blood group typing industry is experiencing rapid growth due to expanding healthcare infrastructure, rising population, and increasing awareness of blood donation. Countries such as India and China are witnessing growing demand for transfusions owing to higher incidence of chronic diseases and trauma cases. Government initiatives aimed at improving blood bank networks and diagnostic capabilities are supporting market expansion. Additionally, increasing adoption of automated and molecular typing technologies is enhancing testing efficiency. The region also benefits from a large patient pool and improved access to healthcare services, making it a key growth area for market players.

The blood group typing market in Japan is driven by advanced healthcare systems and a rapidly aging population, which increases the demand for transfusions. The country emphasizes high standards for blood safety and quality, leading to widespread adoption of advanced diagnostic technologies. Organizations such as the Japanese Red Cross Society manage blood donation and transfusion services efficiently. Japan is also at the forefront of adopting automation and molecular typing methods, ensuring accurate and rapid testing. Continuous technological innovation and strong regulatory frameworks support the steady growth of the market.

The blood group typing market in China is witnessing significant growth due to expanding healthcare infrastructure and increasing government focus on improving diagnostic services. Rising incidence of chronic diseases and increasing surgical procedures are driving transfusion demand. The country is also strengthening its blood donation systems and regulatory standards. Increasing adoption of automated and molecular typing technologies is improving testing accuracy and efficiency. Additionally, domestic and international companies are expanding their presence in China to capitalize on growing opportunities, supported by the country’s large population and improving healthcare access.

Latin America Blood Group Typing Market Trends

Latin America blood group typing industry is experiencing gradual growth, supported by improving healthcare systems and increasing awareness of blood donation. Countries such as Brazil and Mexico are investing in strengthening blood bank infrastructure and transfusion services. Rising prevalence of chronic diseases and trauma cases is increasing the demand for blood typing. However, limited access to advanced technologies in some regions remains a challenge. Governments and healthcare organizations are focusing on improving diagnostic capabilities and ensuring safe transfusion practices, which are expected to support market growth over time.

Middle East & Africa Blood Group Typing Market Trends

The MEA blood group typing industry is growing due to improving healthcare infrastructure and increasing investment in diagnostic services. Countries in the Middle East are focusing on modernizing blood banks and adopting advanced technologies, while Africa is witnessing gradual improvements in transfusion services. Rising incidence of chronic diseases and trauma cases is driving demand for blood typing. Additionally, initiatives by organizations such as the World Health Organization to improve blood safety and donation practices are supporting market development. Despite challenges such as limited resources in some regions, ongoing investments are expected to enhance market growth.

Key Blood Group Typing Company Insights

The blood group typing market is moderately fragmented, with the presence of both multinational corporations and regional players competing across product segments. Despite fragmentation, competition remains intense due to ongoing technological advancements and increasing demand for accurate transfusion diagnostics. Key companies operating in this market include Grifols S.A., Merck KGaA, Bio-Rad Laboratories, Inc., Immucor, Inc., Novacyt Group, Danaher Corporation, Agena Bioscience, Inc., Ortho Clinical Diagnostics, and Quotient, Ltd. These players focus on product innovation, automation, and strategic collaborations to strengthen their market position and expand global reach.

Competitive Benchmarking

Recent Developments

• In May 2024, Thermo Fisher Scientific launched the Applied Biosystems Axiom BloodGenomiX Array, a high-throughput genotyping solution capable of detecting over 260 antigens across 38 blood group systems. The platform supports extended and rare blood group identification with ~99.89% concordance, improving transfusion accuracy. It integrates advanced software for automated data analysis, reducing manual intervention and enhancing workflow efficiency in laboratories.

• In January 2025, Haemonetics Corporation completed the sale of its whole blood assets to GVS S.p.A for USD 67.1 million. The deal includes blood collection, processing, and filtration technologies, along with a manufacturing facility in California. This allows Haemonetics to focus on core business areas while enabling GVS to expand its blood-related product portfolio.

• In January 2026, FDA 510(k) Class II automated blood grouping systems were cleared for use in immunohematology workflows. These systems perform ABO and Rh typing, antigen phenotyping, antibody detection, and compatibility testing. They integrate automated sample handling, centrifugation, and software-based interpretation of agglutination results, improving accuracy and reducing manual errors. Additionally, these platforms support high-throughput, hands-free operations, enhancing efficiency in blood banks and strengthening overall transfusion safety.

• In June 2025, Bio-Rad Laboratories, Inc. completed the acquisition of Stilla Technologies, a developer of next-generation digital PCR systems. The acquisition was finalized on June 30, 2025, following a binding offer earlier that year. This strategic move strengthened Bio-Rad’s molecular diagnostics capabilities, supporting advanced genetic analysis applications, including blood group typing and transfusion diagnostics.

Blood Group Typing Market Report Scope

Global Blood Group Typing Market Report Segmentation

This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2021 to 2033. For this study, Grand View Research has segmented the global blood group typing market report based on product, techniques, test type, and region:

• Product Outlook (Revenue, USD Million, 2021 - 2033)

  • Consumables

  • Instruments

  • Services

• Techniques Outlook (Revenue, USD Million, 2021 - 2033)

  • PCR-based and Microarray Techniques

  • Assay-based Techniques

  • Massively Parallel Sequencing Techniques

  • Other Techniques

• Test Type Outlook (Revenue, USD Million, 2021 - 2033)

  • Antibody Screening

  • HLA Typing

  • Cross-matching Tests

  • ABO Blood Tests

  • Antigen Typing

• Regional Outlook (Revenue, USD Million, 2021 - 2033)

  • North America

    • U.S.

    • Canada

    • Mexico

  • Europe

    • UK

    • Germany

    • France

    • Italy

    • Spain

    • Denmark

    • Sweden

    • Norway

  • Asia Pacific

    • Japan

    • China

    • India

    • Australia

    • South Korea

    • Thailand

  • Latin America

    • Brazil

    • Argentina

  • Middle East & Africa

    • South Africa

    • Saudi Arabia

    • UAE

    • Kuwait

Delivered Customizations

This report has been delivered with the following In-depth customizations