GVR Report cover Brain PET-MRI Systems Market Size, Share & Trends Report

Brain PET-MRI Systems Market Size, Share & Trends Analysis Report By Phase (Clinical, Pre-clinical), By Product (Traditional System, Helium Free System), By End Use, By Region, And Segment Forecasts, 2020 - 2027

  • Report ID: GVR-4-68038-851-0
  • Number of Pages: 140
  • Format: Electronic (PDF)
  • Historical Range: 2016 - 2018
  • Industry: Healthcare

Report Overview

The global brain PET-MRI systems market size was valued at USD 281.1 million in 2019 and is expected to grow at a compound annual growth rate (CAGR) of 5.1% from 2020 to 2027. Positron emission tomography (PET) is majorly used for neurological applications due to its advantage of providing high-resolution and 3-dimensional imaging of functional, physiologic, and molecular targets. Despite its advantage of covering and imaging the whole brain, the images captured by PET technology lacked spatial resolution, had low sensitivity, insufficient attenuation, and needed to scatter correction. Therefore, to overcome these problems, PET devices are combined with other imaging devices mainly magnetic resonance imaging (MRI) for accurate correspondence to the anatomic structures and to pathologic changes.

U.S. brain PET-MRI systems market size

Integration of MRI with PET is considered one of the most effective hybrid imaging systems in the field of neurology. MRI effectiveness in imaging the morphology of the brain and presence of MRI modalities for assessing physiologic and metabolic parameters like perfusion, edema, vascular supply, and functional activation is expected to contribute to its adoption along with PET systems. Therefore, combined information from MRI and PET hybrid imaging system helps in enhanced diagnosis of neurological disorders.

Brain PET-MRI systems have opened new opportunities in multiparametric neuroimaging by simultaneously observing the physiological and biochemical processes of the brain. Therefore, the installation of the device in various medical settings is increasing. As per an article by NCBI, by March 2017, approximately 30 PET-MRI scanners were installed in the U.S. Additionally, companies are conducting studies to understand the effectiveness of MRI-PET scanners on animals as well as humans.

Usage of brain PET-MRI systems for preclinical imaging is gradually increasing, which in turn is creating an opportunity for players to enter this market. In September 2016, Aspect Imaging partnered with Seoul National University to launch Preclinical PET-MRI Complete Solution at World Molecular Imaging Congress (WMIC) in New York. This system was formed combining Aspect Imaging’s M7 compact MRI and SNU novel PET insert “SimPET”. Commercial availability of this device is helping scientists to conduct research in different fields including neurology.

Despite various advantages provided by brain PET-MRI systems in the field of neurology, the development of this device involves various challenges. The three major challenges faced while combining PET MRI units are- placing PET system with photomultiplier tubes (PMTs) into a high magnetic field, proper construction of PET-MRI system, and developing attenuation maps for PET images. PET detector elements create issues around the magnetic field and hence impact the device performance. Currently, measures are being taken to limit this issue. These measures involve usage of optical fibers to guide away light from the magnetic field, usage of avalanche photodiode devices (APDs) instead of PMT, and protecting PMT from the magnetic field. Therefore, challenges faced in developing an effective PET-MRI system may impact market growth.

Phase Insights

The pre-clinical brain PET-MRI systems segment accounted for the largest revenue share of 55.6% in 2019 due to the large number of pre-clinical studies conducted on this device for understanding its efficiency in diagnosing neurological disorders. Additionally, market players are developing pre-clinical brain PET-MRI systems to enter the brain PET-MRI systems market or to maintain a position in the market. Aspect Imaging; Bruker; Mediso Ltd.; MR Solutions; and Cubresa Inc. are some of the market players developing pre-clinical PET-MRI devices for neurology.

Players are forming alliances to expand the reach of their pre-clinical brain PET-MRI systems. In September 2018, Aspect Imaging formed an alliance with Brightonix Imaging for offering SimPET insert to preclinical MRI researchers. This offered insert is compatible with MRI machines having 16 cm to 40 cm bore size and 3.0 T to 11.74 T field strength. The usage of this pre-clinical PET-MRI system is anticipated to help researchers in various fields such as neurology, cardiology, and oncology.

Clinical brain PET-MRI systems are expected to experience the fastest growth of 6.6% during the forecast period. An increasing number of clinical trials for neurological disorders are expected to contribute to segment growth. Over 299 clinical trial studies of brain PET-MRI systems for neurological orders are currently being conducted. Additionally, pre-clinical brain PET-MRI systems are getting effective results in diagnosing neurological disorders and hence are entering into the clinical phase. The positive result of these clinical trial studies is expected to lead to the launch of PET-MRI devices for neurology, which in turn will enhance the growth of the overall market. Additionally, few major players such as Siemens Healthcare has launched PET-MRI system for its usage in various clinical applications mainly neurology. Therefore, an increasing number of clinical studies and the launch of brain PET-MRI systems is expected to boost the market growth.

Product Insights

Traditional PET-MRI held the largest revenue share of 60.8% in 2019 due to the growing development of these devices by the market players. Players such as Siemens Healthcare, GE Healthcare, and Bruker have come up with traditional brain PET-MRI systems that consume helium to cool the magnet. Usage of helium in these MRI machines complicates its functionality and creates problems during its installation. This, in turn, is expected to impact the growth of the segment during the forecast period.

Helium-free brain PET-MRI systems are expected to grow at the fastest rate of 5.6% during the forecast period. The associated cost of helium gets deducted during the development and usage of these devices, which in turn is expected to impact its adoption. Moreover, to overcome the complications associated with traditional brain PET-MRI systems, market players are focusing on enhancing the development of helium-free brain PET-MRI systems. Market players such as MR Solutions and GE Healthcare are focusing on developing helium-free MRI machines, which, later can be integrated with PET systems to develop a helium-free PET-MRI machine. Currently, these players are developing pre-clinical helium-free brain PET-MRI systems to understand its effectiveness in the field of neurology.

MR Solutions came up with a dual field 3T/7T PET-MR scanner which was helium-free for molecular research. Universities and institutes such as Mallinckrodt Institute of Radiology (MIR) at Washington University School of Medicine installed this device to conduct various research in the field of oncology, cardiology, and neurology. In September 2019, this helium-free system by MR Solutions was discussed at the World Molecular Imaging Congress, to understand its usage in pre-clinical research. Additionally, the company has also strengthened its distribution network in Japan, Korea, Australia, and China to increase the adoption of helium-free brain PET-MRI systems. Therefore, the growing focus of market players to develop and study helium-free brain PET-MRI systems will lead to its commercial usage and hence will impact the market growth.

End-use Insights

Hospitals held the largest revenue share of 42.2% in 2019 mainly due to an increasing number of neurological disorders. Around, 500,000 cases of multiple sclerosis, brain tumor, and amyotrophic lateral sclerosis are diagnosed annually. This increase in neurological cases is creating the demand for its diagnosis. Therefore, hospitals are installing brain PET-MRI systems frequently to enhance the diagnosis of neurological disorders. In July 2018, the PET-MRI scanner was installed at Toronto General Hospital for the diagnosis of cancer, cardiac disorders, and neurological disorders. Additionally, in February 2013, Apollo Hospitals launched PET-MRI SUITE at Indraprastha Apollo Hospitals. This suite will accommodate brain PET-MRI systems from various companies to diagnose neurology and cardiology diseases.

Global brain PET-MRI systems market share

Diagnostic imaging centers are expected to experience the fastest growth rate of 5.4% during the forecast period. Patients with neurological disorders prefer diagnostic imaging centers to avoid long wait times and additional costs associated with hospitals. Furthermore, these imaging centers focus on providing enhanced diagnosing by installing advanced hybrid imaging devices such as brain PET-MRI systems. House of Diagnostics center has been established in India which primarily focuses on providing PET-MRI scan services. The services included under PET-MRI scan involves brain PET-MRI, whole-body FDG PET MRI, DOTA whole-body PET MRI, head and neck FDG PET MRI, whole-body FDG PET MRI for cancer screening, and breast only FDG PET MRI. Therefore, the growing focus of diagnostic imaging centers to inflate PET-MRI services for different applications such as neurology is expected to propel segment growth during the forecast period.

Other segment is also expected to grow at a significant rate during the forecast period. Research centers, universities, and institutes are installing mainly pre-clinical PET-MRI system for conducting research on animals to understand the effectiveness of the device in diagnosing neurological disorders. Market players are forming alliances with universities and institutes to launch their device and to increase its reach. In September 2016, Aspect Imaging partnered with Seoul National University’s Department of Nuclear Medicine to commercially present simultaneous preclinical PET-MRI complete solution at the 2016 World Molecular Imaging Congress (WMIC). This commercially available system will help the researchers and scientists to study various fields such as oncology, cardiology, and neurology. Therefore, growing research on brain PET-MRI systems is expected to boost the segment growth.

Regional Insights

Asia Pacific held the largest revenue share of 24.2% in 2019 owing to the increasing adoption of advanced diagnostic machines in research centers and universities established in the region. Rising demand for diagnostic systems from countries including India, Japan, and China is anticipated to drive the market in the region over the forecast period.

North America held a significant revenue share of 24.0% in 2019 largely due to the growing prevalence of neurological disorders in the region. As per the American Neurological Association, the most prevalent neurological disorders recorded in the U.S. include Alzheimer's disease, stroke, traumatic brain injury, epilepsy, multiple sclerosis, and Parkinson's disease. In 2017, the prevalence of Alzheimer's disease in the U.S. was 5.3 million, which is expected to increase during the forecast period. Therefore, to provide a proper diagnosis for neurological disorders, market players are providing brain PET-MRI systems in the U.S. In September 2015, Bruker introduced BioSpec 3T PET-MRI at World Molecular Imaging Congress (WMIC) 2015.

Europe accounted for a decent revenue share in the market in 2019. Growing awareness regarding hybrid imaging in the region is expected to drive the adoption of brain PET-MRI systems in the region for applications such as neurology. ESHIMT (European Society for Hybrid, Molecular, and Translational Imaging) is a non-profit organization in Europe that promotes and coordinates the activities happening in the field of hybrid imaging. Additionally, this non-profit organization conducts various training and educational programs for scientists, technologists, and physicists for advanced hybrid imaging technologies.

Key Companies & Market Share Insights

The market players are undergoing collaborations and partnerships to expand their product portfolio and to increase the reach of their offerings. In February 2019, Cubresa announced a distribution agreement with Worldwide Technology (S.H.) Co., Ltd. to distribute NuPET preclinical imaging products in China. This partnership will enhance the research of brain PET-MRI systems in the field of neurology, cardiology, and oncology in China.

Market players are engaged in various alliances to enter the market in China and India. In January 2019, Cubresa, a company which develops PET inserts for MRI, has formed a joint venture along with private investors and the GaoXin Group. Together they have formed the Sino-Canadian Health Engineering Research Institute (SCHERI). The main aim of this venture is to develop clinical products using advanced BrainPET insert by Cubresa. This insert can be installed into 3T and 1.5T MRI systems for clinical use in the field of neurology. Therefore, initiatives taken by the market players to develop brain PET-MRI and to increase its reach in the APAC region is expected to drive the market growth. Some of the prominent players in the brain PET-MRI systems market include:

  • Siemens Healthineers AG

  • Koninklijke Philips N.V.

  • GE Healthcare

  • Bruker

  • Mediso Ltd.

  • MR Solutions

  • Cubresa Inc.

  • Aspect Imaging

Brain PET-MRI Systems Market Report Scope

Report Attribute


Market size value in 2020

USD 294.9 million

Revenue forecast in 2027

USD 417.7 million

Growth Rate

CAGR of 5.1% from 2020 to 2027

Base year for estimation


Historical data

2016 - 2018

Forecast period

2020 - 2027

Quantitative units

Volume in Units, Revenue in USD million and CAGR from 2020 to 2027

Report coverage

Revenue forecast, company ranking, competitive landscape, growth factors, and trends

Segments covered

Phase, product, end use, region

Regional scope

North America; Europe; Asia Pacific; Latin America; MEA

Country scope

U.S.; Canada; U.K.; Germany; France; Italy; Spain; Russia; Netherlands; Switzerland; Turkey; Poland; China; India; Japan; Thailand; South Korea; Indonesia; Taiwan; Hong Kong; Philippines; Malaysia; Mexico; Brazil; Colombia; Argentina; Chile; South Africa; Saudi Arabia; UAE; Iran; Qatar

Key companies profiled

Siemens Healthineers AG; Koninklijke Philips N.V.; GE Healthcare; Bruker; Mediso Ltd.; MR Solutions; Cubresa Inc.; Aspect Imaging

Customization scope

Free report customization (equivalent up to 8 analysts working days) with purchase. Addition or alteration to country, regional & segment scope.

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Segments Covered in the Report

This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2016 to 2027. For the purpose of this study, Grand View Research has segmented the global brain PET-MRI systems market report on the basis of phase, product, end use, and region:

  • Phase Outlook (Volume, Units; Revenue, USD Million, 2016 - 2027)

    • Clinical

    • Pre-clinical

  • Product Outlook (Volume, Units; Revenue, USD Million, 2016 - 2027)

    • Traditional PET-MRI systems

    • Helium-free PET-MRI systems

  • End-use Outlook (Volume, Units; Revenue, USD Million, 2016 - 2027)

    • Hospitals

    • Diagnostic imaging centers

    • Others

  • Regional Outlook (Volume, Units; Revenue, USD Million, 2016 - 2027)

    • North America

      • U.S.

      • Canada

    • Europe

      • Germany

      • U.K.

      • France

      • Italy

      • Spain

      • Russia

      • Netherlands

      • Switzerland

      • Turkey

      • Poland

    • Asia Pacific

      • China

      • Japan

      • India

      • Thailand

      • South Korea

      • Indonesia

      • Taiwan

      • Hong Kong

      • Philippines

      • Malaysia

    • Latin America

      • Brazil

      • Mexico

      • Argentina

      • Colombia

      • Chile

    • Middle East & Africa

      • South Africa

      • Saudi Arabia

      • UAE

      • Iran

      • Qatar

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