GVR Report cover Human Immunodeficiency Virus Therapeutics Market Size, Share & Trends Report

Human Immunodeficiency Virus Therapeutics Market Size, Share & Trends Analysis Report By Drug Class (Nucleoside-Analog Reverse Transcriptase Inhibitors (NRTIs), Non-NRTIs, Entry & Fusion, Protease), And Segment Forecasts, 2018 - 2025

  • Report ID: GVR-1-68038-210-5
  • Number of Pages: 75
  • Format: Electronic (PDF)
  • Historical Range: 2014 - 2015
  • Industry: Healthcare

Industry Insights

The global Human Immunodeficiency Virus (HIV)-1 therapeutics market was valued at USD 13.5 billion in the year 2015 and is estimated to grow at a CAGR of 1.4% from 2016 to 2025. The market growth can be linked to the surging incidence rate of HIV-1 infection, which unlike the death rate from this viral infection, has not changed substantially over the years as per the Institute for Health Metrics and Evaluation.

This is one of the most challenging diseases the world has ever experienced. Approximately 35 million people across the globe are affected by it. However, among this population, only half the patient number has access to antiretroviral treatments for disease management. Among the two strains of the human immunodeficiency virus, HIV-1 is more prominent and accounts for around 95% of all the infections worldwide.

U.S. HIV-1 therapeutics market revenue, by drug class, 2014 - 2025 (USD Billion)

U.S. HIV-1 therapeutics market

The number of people contracting this viral infection is rapidly increasing worldwide. The disease has mostly affected the developing and underdeveloped countries on a larger scale due to the lack of adequate prevention measures and treatment facilities. Although there is no permanent cure for this infection at present, it can be controlled with proper medical care and drug therapy.

Medical treatment for this debilitating disease enables patients to live a normal life by reducing the intensity of the disease and increasing the survival time. Patients are rapidly diagnosed at present due to technological advancements in point-of-care testing for HIV. Thus, enabling early interventions to prevent disease progression to an advanced stage

The factors responsible for the growing prevalence rate include unprotected sex, contaminated needles or syringes, and majorly the lack of awareness about the mode of transmission. A vital factor driving the HIV-1 market growth is the concerted efforts of the government and various NGOs to provide at-risk individuals with greater accessibility to disease testing and treatment for infected persons.

Several companies, such as Cipla, Inc. and Gilead Sciences, Inc., have also adopted patient education programs to reduce the adverse consequences of the infection. The future growth of this market largely depends upon the unmet diagnostic and treatment needs present in the African and Asian countries.

Drug Classes Insights

On the basis of drug classes, the HIV-1 therapeutics market is segmented into six classes, namely, NRTIs, Non-NRTIs, entry and fusion inhibitors, protease inhibitors, integrase inhibitors, and coreceptor antagonists. Most of the anti-retroviral drugs belong to the NRTIs group, thus rendering it the largest class of drugs.

HIV-1 Therapeutics market, by drug class, 2015

HIV-1 Therapeutics market

In 2015, the NRTIs segment accounted for over 40% of the market share. NRTIs inhibit reverse transcriptase activity and ultimately arrest viral replication. Generally, the anti-retroviral regimen employed to treat HIV patients involves a combination of anti-retroviral agents belonging to different drug classes, wherein the primary goal is to reduce the viral load. Currently, more than 20 drugs approved by the U.S. Food and Drug Administration (FDA) are commercially available.

Regional Insights

North America was the largest HIV-1 therapeutics market in 2015 owing to the high treatment expense, increasing prevalence, and the introduction of drugs with improved efficacy such as Complera by Gilead Sciences, Inc. In 2016, North America and Europe together rare accounting for a high prevalence of 2.4 million people suffering from this infection.

Nearly 5.1 million people in Asia Pacific and more than 1.6 million people in the Latin American region are living with this infection. The African market is expected to be one of the fastest-growing markets, growing at a CAGR of over 2% during the forecast period. The African countries are vastly affected with more than 25 million people infected, which accounted for 71% of the global count in 2015.

Competitive insights

Gilead Sciences, Inc. is the leader in the sector offering a vast anti-retroviral portfolio followed by ViiV Healthcare. ViiV Healthcare is a joint venture by GlaxoSmithKline, Pfizer, and Shionogi. These companies transferred their HIV Assets to ViiV Healthcare as a part of their expansion strategy to attain a higher market share.

Furthermore, the additional key players in the global HIV-1 therapeutics industry include AbbVie, Inc.(U.S.), Merck & Co., Inc. (U.S.), Bristol-Myers Squibb Company (U.S.), Boehringer Ingelheim GmbH (Germany), Genentech, Inc. (U.S.), Cipla, Inc. (India), etc.

Report Scope



Base year for estimation


Actual estimates/Historic data

2014 - 2015

Forecast period

2016 - 2025

Market representation

Revenue in USD Million & CAGR from 2016 to 2025

Regional scope

North America, Europe, Asia Pacific, Latin America & MEA

Country scope

U.S., Canada, UK, Germany, Japan, China, India, Brazil, Mexico, South Africa

Report coverage             

Revenue forecast, company share, competitive landscape, growth factors and trends

15% free customization scope(equivalent to 5 analyst working days)

If you need specific market information, which is not currently within the scope of the report, we will provide it to you as a part of customization

Segments Covered in the Report

This report forecasts revenue growth at global, regional & country levels and provides an analysis of the latest trends and opportunities in each of the sub-segments from 2014 to 2025. For the purpose of this study, Grand View Research has segmented the HIV-1 therapeutics market on the basis of drug class, and region:

  • Drug Class Outlook (USD Million; 2014 - 2025)

    • Nucleoside-Analog Reverse Transcriptase Inhibitors (NRTIs)

    • Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs)

    • Entry and Fusion Inhibitors

    • Protease Inhibitors (PIs)

    • Integrase Inhibitors

    • Coreceptor Antagonists

  • Regional Outlook (Revenue, USD Million; 2014 - 2025)

    • North America

      • The U.S.

      • Canada

    • Europe

      • Germany

      • U.K.

    • Asia Pacific

      • China

      • Japan

      • India

    • Latin America

      • Mexico

      • Brazil

    • MEA

      • South Africa

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