Local Anesthesia Drugs Market Size, Share & Trends Analysis Report By Drug (Bupivacaine, Ropivacaine, Lidocaine), By Application (Injectable, Surface Anesthetic), By Region, And Segment Forecasts, 2024 - 2030

Local Anesthesia Drugs Market Trends

The global local anesthesia drugs market size was valued at USD 4.01 billion in 2023 and is projected to grow at a CAGR of 3.6% from 2024 to 2030. The rise in the geriatric population, who are more prone to chronic diseases and surgeries, is a significant driver contributing to the growth of the market. For instance, according to an article published by the World Health Organization in October 2022, the proportion of the population above 60 years of age is expected to reach 22% by 2050. In addition, an increase in surgical procedures such as cosmetic surgeries, plastic surgeries, and dental procedures globally are further expected to foster market growth.

The development of advanced technologies in drug delivery is anticipated to boost the market growth. Local anesthetic drug delivery systems, such as lipid-based, have been an effective treatment option in pain management. It has its application in various treatments such as third molar extractions, cesarean sections, mastectomies, and open-heart surgeries.

The low systemic toxicity and greater efficacy of non-conventional local anesthetics have led to the development of nanotechnology-based delivery approaches. The rising demographic changes are driving people to focus on aesthetic value and expect minimally invasive, painless, and effective procedures to improve their looks and self-confidence. For instance, according to a report published by the Aesthetic Society in 2022, total aesthetic procedures increased by 14% in 2022.

Drugs such as ropivacaine, mepivacaine, and tetracaine are used for such procedures. For the dermatologic procedures, topical anesthetics are used. Topical lidocaine Eutectic Mixture of Local Anesthetics (EMLA) is the most commonly used topical anesthetic. Cryoanesthesia is also used to cool the area and relieve pain. Therefore, the increasing number of aesthetic procedures is expected to impact the market positively.

Other advancements include local anesthesia being used for zygomatic implants. For instance, in 2023, according to the Journal of Oral Medicine and Oral Surgery, 54 zygomatic implant placements under local anesthesia were performed in 25 patients between 2019 and 2022. All these factors have contributed significantly to adopting and accepting the use of local anesthetic drugs for various treatment-related procedures.

Section 505(b) of the Federal Food, Drug, and Cosmetic Act (FD&C Act) has proposed guidance to assist sponsors in developing local anesthetic drug products and to produce postoperative analgesia for a prolonged duration, for which submission of a new drug application (NDA) is required. These guidelines and regulations have impacted the market and production of local anesthetic drugs in a positive way.

Drug Insights

Lidocaine dominated the market and accounted for a market share of 28.7% in 2023. It can be attributed to the extensive use of injectable and topical anesthetics. For instance, according to the study published in January 2023 by the National Center for Biotechnology Information (NCBI), research was conducted where lidocaine transdermal patches were used to reduce the pain intensity in neuropathic cancer patients, already been treated with opioid treatment. Lidocaine, which is a local anesthetic drug, has been used as part of multimodal pain management strategies to reduce opioid use and avoid possible side effects.

Ropivacaine is expected to register the fastest CAGR during the forecast period. It can be attributed to the favorable safety profile and longer duration of action compared to other local anesthetics such as bupivacaine and prilocaine. For instance, according to the World Journal of Hernia and Abdominal Wall Surgery, in 2024, research was conducted where ropivacaine was used to demonstrate safety and efficacy in open inguinal hernia repair. It is used as a part of multimodal pain management strategies, which is expected to contribute to the growth of the local anesthetic drugs market.

Application Insights

Injectables accounted for the largest market revenue share of 59.5% in 2023. It can be attributed to their increasing use in surgical procedures. Computer-based local anesthetic delivery and vibrotactile devices are expected to contribute to the demand for these drugs in surgical procedures. For instance, according to an article published by the Drug Delivery journal in 2023, Exparel is a local anesthetic formed by the DepoFoam technology using bupivacaine liposome suspension for injection. Such developments are likely to boost the market growth.

In February 2024, PK Med, a biotechnology company, received the U.S. FDA approval to advance its Phase II clinical trials for PKM-01, an injectable gout treatment of the company. The trial is expected to evaluate the effectiveness of three doses of PKM-01, which offers a combined treatment of controlled-release colchicine and the anesthetic ropivacaine. The development of such injectable treatment options is further expected to drive market growth.

Surface anesthetic is expected to register the fastest CAGR during the forecast period. It is attributed to the advancements in drug delivery systems. It is used to numb the skin, subcutaneous tissue, and peripheral nerves for invasive or surgical procedures. It offers improved potency, onset, and duration of action compared to other traditional lidocaine and bupivacaine drugs. Surface anesthetic is also used during cataract surgery. Thus, the various applications of surface anesthetic have boosted this segment’s growth in the local anesthetic market.

Regional Insights

North America local anesthetic drugs market dominated with a market share of 35.4% in 2023. It is attributed to the high prevalence of chronic diseases, growing geriatric population, high per capita income, improved access to healthcare, and development of infrastructure in this region. For instance, according to the NCBI, more than 53% of the geriatric population has periodontitis disorders. The greatest risk factor for dental diseases is aging, which is anticipated to impact the North America local anesthesia drugs market.

U.S. Local Anesthesia Drugs Market Trends

The U.S. local anesthesia drugs market dominated the global market with a share of 29.4% in 2023. It is attributed to the increase in the aging population, and the rise in surgical procedures for dental, plastic, and cosmetic surgeries. The rising awareness for oral hygiene has boosted this market to grow. For instance, according to the report of the American Dental Association's Health Policy Institute in 2023, about 3,616 patients visited for dental checkups. Thus, these factors have been contributing to drive the market’s growth.

Asia Pacific Local Anesthetic Drugs Market Trends

Asia Pacific local anesthetic drugs market was identified as a lucrative region in 2023. It is attributed to the rising geriatric population, rise in chronic disease, advancement in surgical procedures, and lower use of opioid-based drugs. For instance, according to the World Economic Forum, in 2023, it was stated that more than 1 in 10 people in Japan are aged 80 or over. Thereby, the prevalence of chronic diseases would increase the surgical procedures and usage of local anesthesia. Thus boosting the market’s growth.

Europe local anesthesia drugs Market Trends

Europe local anesthesia drugs market is anticipated to witness significant growth over the forecast period. It is attributed to the increase in cosmetic surgeries, growing use of local anesthetics in post-operative and advancement in surgical procedures pain management. For instance, in 2022, around 60 thousand eyelid surgeries were performed in Germany, owing to people becoming aware of common face and head cosmetic procedures. Thereby, helping the local anesthesia drugs market to grow positively in this region.

MEA Local Anesthesia Drugs Market Trends

MEA local anesthesia drugs market is anticipated to witness significant growth in local anesthesia drugs market. Though it holds a low market share value but is in greater demand due to growing public awareness. Demographic shifts in the Middle East and Africa, such as urbanization and lifestyle changes, rise in chronic diseases may also contribute to the growing demand for local anesthesia drugs, thereby increasing the market growth in this region.

Key Local Anesthesia Drugs Company Insights

Some of the key companies in the local anesthesia drugs market include Johnson & Johnson Services Inc, Pfizer Inc., AstraZeneca plc, Novartis AG. These companies are growing their market revenue by launching new products, collaborations and adopting various other strategies.

• Pfizer Inc. is a pharmaceutical and biomedical company that also engages in the production of local anesthesia drugs. It distributes more than 315 drugs in the U.S., along with anesthetic agents like bupivacaine and lidocaine, for pain management procedures. Its contribution to anesthesia drugs has spurred its market revenue share to grow.

• Teva Pharmaceutical Industries Ltd is a global generic drug manufacturer, including a wide range of local anesthetic agents. Products include lidocaine patches, lidocaine injections, and other generic versions of branded local anesthetics like bupivacaine. It is a major supplier of generic local anesthesia drugs worldwide, benefiting from the growing demand for these products driven by the increasing number of surgical procedures globally, thereby increasing the market share revenue of the company.

Recent Developments

• In April 2024, Baxter International Inc. expanded its pharmaceuticals portfolio with five product launches in the U.S. One such product launch includes, ropivacaine hydrochloride injection, which is a single-dose infusion bag and ready-to-use that produces local or regional anesthesia for surgery and acute pain management.

• In April 2023, FFF Enterprises Inc. announced that it had entered an exclusive partnership with Sintetica US to provide Lidocaine Hydrochloride Injection and to mark its presence globally.

• In December 2021, Hikima Pharmaceuticals PLC announced the launch of Bupivacaine HCl Injection, which is used in surgery, dental and oral surgery procedures, diagnostic and therapeutic procedures, and obstetrical procedures.

Local Anesthesia Drugs Market Report Scope

Global Local Anesthesia Drugs Market Report Segmentation

This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2018 to 2030. For this study, Grand View Research has segmented the local anesthesia drugs market report based on drug, application, and region.

• Drug Outlook (Revenue, USD Million, 2018 - 2030)

  • Bupivacaine

  • Ropivacaine

  • Lidocaine

  • Chloroprocaine

  • Prilocaine

  • Benzocaine

  • Others

• Application Outlook (Revenue, USD Million, 2018 - 2030)

  • Injectable

  • Surface Anesthetic

• Regional Outlook (Revenue, USD Million; 2018 - 2030)

  • North America

    • U.S.

    • Canada

    • Mexico

  • Europe

    • UK

    • Germany

    • France

    • Italy

    • Spain

    • Denmark

    • Sweden

    • Norway

  • Asia Pacific

    • Japan

    • China

    • India

    • Australia

    • South Korea

    • Thailand

  • Latin America

    • Brazil

    • Argentina

  • MEA

    • South Africa

    • Saudi Arabia

    • UAE

    • Kuwait