Mesenchymal Stem Cells Market Size, Share & Trends Report

Mesenchymal Stem Cells Market Size, Share & Trends Analysis Report By Product & Services, By Workflow, By Type, By Source Of Isolation, By Indication, By Application, By Region, And Segment Forecasts, 2023 - 2030

  • Report ID: GVR-4-68039-361-1
  • Number of Pages: 150
  • Format: Electronic (PDF)
  • Historical Range: 2018 - 2021
  • Industry: Healthcare

Research Methodology

A three-pronged approach was followed for deducing the mesenchymal stem cells market estimates and forecasts. The process has three steps: information procurement, analysis, and validation. The whole process is cyclical, and steps repeat until the estimates are validated. The three steps are explained in detail below:

Information procurement: Information procurement is one of the most extensive and important stages in our research process, and quality data is critical for accurate analysis. We followed a multi-channel data collection process for mesenchymal stem cells market to gather the most reliable and current information possible.

  • We buy access to paid databases such as Hoover’s and Factiva for company financials, industry information, white papers, industry journals, SME journals, and more.
  • We tap into Grand View’s proprietary database of data points and insights from active and archived monitoring and reporting.
  • We conduct primary research with industry experts through questionnaires and one-on-one phone interviews.
  • We pull from reliable secondary sources such as white papers and government statistics, published by organizations like WHO, NGOs, World Bank, etc., Key Opinion Leaders (KoL) publications, company filings, investor documents, and more.
  • We purchase and review investor analyst reports, broker reports, academic commentary, government quotes, and wealth management publications for insightful third-party perspectives.

Analysis: We mine the data collected to establish baselines for forecasting, identify trends and opportunities, gain insight into consumer demographics and drivers, and so much more. We utilized different methods of mesenchymal stem cells market data depending on the type of information we’re trying to uncover in our research.

  • Market Research Efforts: Bottom-up Approach for estimating and forecasting demand size and opportunity, top-down Approach for new product forecasting and penetration, and combined approach of both Bottom-up and Top-down for full coverage analysis.

  • Value-Chain-Based Sizing & Forecasting: Supply-side estimates for understanding potential revenue through competitive benchmarking, forecasting, and penetration modeling.

  • Demand-side estimates for identifying parent and ancillary markets, segment modeling, and heuristic forecasting.

  • Qualitative Functional Deployment (QFD) Modelling for market share assessment.

Market formulation and validation: We mine the data collected to establish baselines for forecasting, identify trends and opportunities, gain insight into consumer demographics and drivers, and so much more. We utilize different methods of data analysis depending on the type of information we’re trying to uncover in our research.

  • Market Formulation: This step involves the finalization of market numbers. This step on an internal level is designed to manage outputs from the Data Analysis step.

  • Data Normalization: The final market estimates and forecasts are then aligned and sent to industry experts, in-panel quality control managers for validation.

  • This step also entails the finalization of the report scope and data representation pattern.

  • Validation: The process entails multiple levels of validation. All these steps run in parallel, and the study is forwarded for publishing only if all three levels render validated results.

Mesenchymal Stem Cells Market Categorization:

The mesenchymal stem cells market was categorized into seven segments, namely products and services (Products, Services), workflow (Cell Sourcing & Isolation, Culture & Cryopreservation, Differentiation, Characterization), type (Autologous, Allogeneic), source of isolation (Bone Marrow, Cord Blood, Peripheral Blood, Fallopian Tube, Fetal Liver, Lung, Adipose Tissues), indication (Bone And Cartilage Repair, Cardiovascular Disease, Inflammatory And Immunological Diseases, Liver Diseases, Cancer, GvHD), application (Disease Modelling, Drug Development & Discovery, Stem Cell Banking, Tissue Engineering, Toxicology Studies), and regions (North America, Europe, Asia Pacific, Latin America, Middle East & Africa).

Segment Market Methodology:

The mesenchymal stem cells market was segmented into products and services, workflow, type, source of isolation, indication, application, and regions. The demand at a segment level was deduced using a funnel method. Concepts like the TAM, SAM, SOM, etc., were put into practice to understand the demand. We at GVR deploy three methods to deduce market estimates and determine forecasts. These methods are explained below:

Market research approaches: Bottom-up

  • Demand estimation of each product across countries/regions summed up to from the total market.

  • Variable analysis for demand forecast.

  • Demand estimation via analyzing paid database, and company financials either via annual reports or paid database.

  • Primary interviews for data revalidation and insight collection.

Market research approaches: Top-down

  • Used extensively for new product forecasting or analyzing penetration levels.

  • Tool used invoice product flow and penetration models Use of regression multi-variant analysis for forecasting Involves extensive use of paid and public databases.

  • Primary interviews and vendor-based primary research for variable impact analysis.

Market research approaches: Combined

  • This is the most common method. We apply concepts from both the top-down and bottom-up approaches to arrive at a viable conclusion.

Regional Market Methodology:

The mesenchymal stem cells market was analyzed at a regional level. The global was divided into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa, keeping in focus variables like consumption patterns, export-import regulations, consumer expectations, etc. These regions were further divided into twenty-three countries, namely, the U.S.; Canada; Germany; the UK; France; Italy; Spain; Denmark; Sweden; Norway; China; Japan; India; South Korea; Australia; Thailand; Brazil; Mexico, Argentina; South Africa; Saudi Arabia, UAE; Kuwait.

All three above-mentioned market research methodologies were applied to arrive at regional-level conclusions. The regions were then summed up to form the global market.

Mesenchymal stem cells market companies & financials:

The mesenchymal stem cells market was analyzed via companies operating in the sector. Analyzing these companies and cross-referencing them to the demand equation helped us validate our assumptions and conclusions. Key market players analyzed include:

  • Thermo Fisher Scientific, Inc. manufactures & provides laboratory reagents, equipment, analytical instruments, consumables, & diagnostic products. The company operates through numerous brands like Thermo Scientific, Applied Biosystems, Fisher Scientific, Invitrogen, and Unity Lab Services. It functions through four reportable segments: specialty diagnostics, life sciences solutions, analytical instruments, and laboratory products & services. Clinical next-generation sequencing, biosciences, bioproduction, and genetic sciences are four businesses involved in the life sciences solutions segment. The biosciences segment offers products, such as cell culture media, reagents, consumables, & instruments, which help customers conduct medical & biological research and discover new vaccines & drugs. End-user industries include pharmaceutical & biotechnology companies, clinical diagnostics laboratories, hospitals, government agencies, and research institutes.

  • Axol Bioscience Ltd,  functions in the biotechnology industry and is considered one of the major players in the stem cells market. It has a robust portfolio of products & services, providing different cells, iPSC-derived lines, iPSC services, & technical expertise for iPSC-based systems. Its portfolio comprises media and reagents required for various cell processes. The company functions in various countries, such as China, Japan, Indonesia, Malaysia, India, Taiwan, and Korea, through its distributors.

  • STEMCELL Technologies, it is a Canadian biotechnology business that supports research in life sciences. The company offers cell isolation products, cell culture media & supplements, primary & cultured cells, matrices, cytokines, substrates for immunology, stem cells, regenerative medicine, cancer, & cell therapy research. It offers contract research services, custom solutions, instrument services, and training programs for cell-related activities. The company operates in various regions, such as North America, Europe, and Asia. It has a robust distributor network through which it operates in around 25 countries.

  • Merck KGaA is a German multinational company that provides healthcare solutions & materials. It functions through three sectors: healthcare, life sciences, and performance materials. The company works in North America, Europe, Asia, Latin America, Oceania, and Africa. It provides products related to the biopharma industry, consumer health, biosimilars, and life sciences. In November 2015, Merck declared the acquisition of Sigma-Aldrich Co. LLC, which now works as its subsidiary.

  • Lonza is a global supplier of biopharmaceuticals and offers products related to bio research, consumer care, agro ingredients, pharmaceutical & biotechnology, water treatment, industrial solutions, and wood protection. The company’s market is segmented into pharma & biotech and specialty ingredients. Lonza has operations in North America, Europe, Asia, and other countries, with more than 100 sites & offices across the globe. The company focused on reorganizing its Emerging Technologies business in 2017, owing to rapid growth in global cell & gene therapies research.

  • PromoCell GmbH is a biotechnology company with a cell biology & cell culture product portfolio. The products include stem cells, human primary cells, blood cells, and optimized products for 3D cell culture & cancer. The company also offers mesenchymal stem cells. Its products are used in in-depth cell culture analysis. The company has a global presence with operations in more than 50 countries. In addition, the company offers over 100 ISO-certified training courses through PromoCell Academy.

  • Cyagen is a global company of custom-engineered rat & mouse models. The company also offers a wide range of stem cell products, such as cell lines, media, and differentiation kits that are used for research purposes. It has proficiency in ready-to-use Knockout (KO) catalog models, custom genetically modified rodent models, tailor-made DNA vectors, research-use viruses, and the production of research-use stem cells accompanied with related culture reagents. Cyagen works in the Asia region through its offices in Japan & China.

  • Celprogen Inc. is an American biotechnology company involved in the development of research & therapeutic products based on stem cells. The company’s biological products are often used for regenerative medicine in areas such as oncology, cardiology, neurology, and diabetes. It has an extensive portfolio of biological products, including cancer stem cells, stem cells, iPCs & media. The company offers novel therapeutic and molecular diagnostics product development solutions for in vitro diagnostics, pharmaceuticals, biotechnology, and academic partnerships for drug discovery. Celprogen operates through three core divisions—therapeutic, life sciences, and devices.

  • Cellcolabs is a biotechnology company. The company offers Mesenchymal stem cells (MSCs) for preclinical and clinical applications. It produces its MSC according to the GMP standards & regulations for the GMP line and the GMP-like process for the research grade line. The company can also provide custom-made MSC products. The company offers its products through its distributors like ARP, Atlantis Bioscience, CliniSciences, 2BScientific, and BIOZOL.

  • Stemedica Cell Technologies, Inc. is a clinical-stage biopharmaceutical company dedicated to developing & commercializing progenitor cells, protein, and combination therapies to treat various disorders. The company’s first lead drug candidate is ischemia-tolerant mesenchymal stem cells (itMSCs), an allogeneic progenitor cell therapy under investigation for the treatment of ischemic stroke & Alzheimer’s disease. The company’s second drug candidate is ischemia-tolerant neural progenitor cells (itNSCs), an allogeneic cell therapy under investigation for treating spinal cord injury. Furthermore, the company has pipeline MSCs for various conditions like chronic heart failure, acute myocardial infarction, and traumatic brain injury, among others. Its manufacturing facilities comply with Current Good Manufacturing Practices (cGMP).

Value chain-based sizing & forecasting

Supply Side Estimates

  • Company revenue estimation via referring to annual reports, investor presentations, and Hoover’s.

  • Segment revenue determination via variable analysis and penetration modeling.

  • Competitive benchmarking to identify market leaders and their collective revenue shares.

  • Forecasting via analyzing commercialization rates, pipelines, market initiatives, distribution networks, etc.

Demand side estimates

  • Identifying parent markets and ancillary markets

  • Segment penetration analysis to obtain pertinent

  • revenue/volume

  • Heuristic forecasting with the help of subject matter experts

  • Forecasting via variable analysis

Mesenchymal Stem Cells Market Report Objectives:

  • Understanding market dynamics (in terms of drivers, restraints, & opportunities) in the countries.

  • Understanding trends & variables in the individual countries & their impact on growth and using analytical tools to provide high-level insights into the market dynamics and the associated growth pattern.

  • Understanding market estimates and forecasts (with the base year as 2022, historic information from 2018 to 2021, and forecast from 2023 to 2030). Regional estimates & forecasts for each category are available and are summed up to form the global market estimates.

Mesenchymal Stem Cells Market Report Assumptions:

  • The report provides market value for the base year 2022 and a yearly forecast till 2030 in terms of revenue/volume or both. The market for each of the segment outlooks has been provided on region & country basis for the above-mentioned forecast period.

  • The key industry dynamics, major technological trends, and application markets are evaluated to understand their impact on the demand for the forecast period. The growth rates were estimated using correlation, regression, and time-series analysis.

  • We have used the bottom-up approach for market sizing, analyzing key regional markets, dynamics, & trends for various products and end-users. The total market has been estimated by integrating the country markets.

  • All market estimates and forecasts have been validated through primary interviews with the key industry participants.

  • Inflation has not been accounted for to estimate and forecast the market.

  • Numbers may not add up due to rounding off.

  • Europe consists of EU-8, Central & Eastern Europe, along with the Commonwealth of Independent States (CIS).

  • Asia Pacific includes South Asia, East Asia, Southeast Asia, and Oceania (Australia & New Zealand).

  • Latin America includes Central American countries and the South American continent

  • Middle East includes Western Asia (as assigned by the UN Statistics Division) and the African continent.

Primary Research

GVR strives to procure the latest and unique information for reports directly from industry experts, which gives it a competitive edge. Quality is of utmost importance to us, therefore every year we focus on increasing our experts’ panel. Primary interviews are one of the critical steps in identifying recent market trends and scenarios. This process enables us to justify and validate our market estimates and forecasts to our clients. With more than 8,000 reports in our database, we have connected with some key opinion leaders across various domains, including healthcare, technology, consumer goods, and the chemical sector. Our process starts with identifying the right platform for a particular type of report, i.e., emails, LinkedIn, seminars, or telephonic conversation, as every report is unique and requires a differentiated approach.

We send out questionnaires to different experts from various regions/ countries, which is dependent on the following factors:

  • Report/Market scope: If the market study is global, we send questionnaires to industry experts across various regions, including North America, Europe, Asia Pacific, Latin America, and MEA.

  • Market Penetration: If the market is driven by technological advancements, population density, disease prevalence, or other factors, we identify experts and send out questionnaires based on region or country dominance.

The time to start receiving responses from industry experts varies based on how niche or well-penetrated the market is. Our reports include a detailed chapter on the KoL opinion section, which helps our clients understand the perspective of experts already in the market space.

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