The global neglected tropical disease (NTD) treatment market size was valued at USD 1.2 billion in 2018 and is expected to grow at a CAGR of 5.5% over the forecast period. Formal recognition of NTDs in the Sustainable Development Goals (SDG), a United Nations Development Programme, as a global target is anticipated to fuel the market growth.
Rise in the number of programs to tackle NTDs is expected to positively impact the market. For instance, in 2000, WHO launched Global Programme to Eliminate Lymphatic Filariasis (GPELF) with a target of eliminating the disease by 2020. This program aims to prevent the spread of transmission and to alleviate suffering of those already affected by the disease.
Furthermore, the U.S. Agency for International Development (USAID) started a neglected tropical diseases (NTD) program in 2006, majorly focusing on eliminating or controlling blinding trachoma, lymphatic filariasis, schistosomiasis, and three soil transmitted helminths through administration of effective and safe medicines.
The NTD program has expanded its support to 31 countries in Asia, Latin America and Africa. In addition, it has provided more than 2.6 billion treatments and leveraged more than USD 22.3 billion in donated medicines.
Based on disease, the NTD treatment market has been classified into dengue, rabies, trachoma, Buruli ulcer, yaws, leprosy, Chagas disease, human African trypanosomiasis (sleeping sickness), leishmaniases, soil-transmitted helminthiases, and others.
Dengue held the largest segment share in 2018 owing to its increasing prevalence. According to data published in the WHO, around 390 million dengue infections are observed per year globally.
Furthermore, on the basis of studies published in the Epidemiological Update Dengue by the WHO and Pan American Health Organization, in 2018, 16 countries and territories in America reported an increase in dengue cases nationally in comparison to 2017 cases. Moreover, in the first 6 weeks of 2019, there were around 99,998 dengue cases reported in America which accounts for 10.2 cases per 100,000 population including 28 deaths.
Buruli ulcer is estimated to be the fastest growing segment over the forecast period owing to rising awareness of the disease. For instance, Global Buruli Ulcer Initiative (GBUI), a partnership initiative of WHO, Member states, donors, research & academic institutions, non-governmental organizations and others, is dedicated to raise awareness of Buruli ulcer.
The initiative aims to obtain commitments from policymakers, governments and donors for support & development of health systems of endemic countries and for research and control in order to improve access to early diagnosis and treatment.
Based on product type, the market is segmented into drugs and vaccines. In 2018, drugs were anticipated to be the largest product type segment owing to its cost effectiveness and patient compliance especially for oral drug formulations.
Vaccines were estimated to witness fastest growth over the forecast period due to presence of pipeline products. For instance, Takeda Pharmaceutical Company Limited is developing vaccine for dengue, TAK-003 which is currently under phase III clinical trials. The clinical development program consists of 5 phase III trials which includes DEN-304, DEN-305, DEN-314, DEN-301, and DEN-315.
In addition, Merck & Co. Inc., is developing a vaccine for dengue, V180, which is currently under Phase I clinical trial in the U.S. & Australia and is likely to target dengue-endemic Latin America and Asia Pacific regions.
NTDs are endemic to around 150 countries and have affected people across the globe. Asia Pacific dominated the neglected tropical disease treatment market in 2018 and is expected to contribute around 31% of the revenue share. High prevalence of NTDs in the region, continuous increase in the GDP rate, and presence of a huge target population is anticipated to support the market growth.
However, over the forecast period, Latin America is anticipated to witness the fastest growth. Rising awareness and untapped potential for treatment of patients with NTDs in Latin American countries regarding ways of tackling NTDs are expected to accelerate the growth of this regional market.
MEA held the second largest regional share in 2018 owing to increasing burden of neglected tropical diseases in this region. According to the statistics published in the Uniting to Combat NTDs in 2017, more than 600 million people are affected with NTDs in Africa.
Some of the key players in this market include F. Hoffmann-La Roche Ltd, Bayer AG, GlaxoSmithKline plc, Novartis AG, Pfizer, Inc., Eisai Co. Ltd., Sanofi, Astellas Pharma, Takeda Pharmaceutical Company Limited and Gilead Sciences.
New product development, collaborations and partnerships are some of the common strategies adopted by key players in the market. For instance, Eisai Co. Ltd. is developing E1224 (Fosravuconazole) for the treatment of Chagas disease and is currently under phase II clinical trial.
Base year for estimation
Actual estimates/Historical data
2015 - 2017
2019 - 2026
Revenue in USD Million & CAGR from 2018 to 2026
North America, Europe, Asia Pacific, Latin America, MEA
Revenue forecast, company share, competitive landscape, growth factors, and trends
U.S., Canada, U.K., Germany, Japan, China, India, Indonesia, Singapore, Philippines, Brazil, Mexico, Argentina, Colombia, Bolivia, South Africa, Saudi Arabia, UAE, Nigeria, Ghana, Zimbabwe
15% free customization scope (equivalent to 5-analyst working days)
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This report forecasts revenue growth at global, regional & country levels and provides an analysis on the industry trends in each of the sub-segments from 2015 to 2026. For the purpose of this study, Grand View Research has segmented the global neglected tropical disease treatment market on the basis of disease, product type and region:
Disease Outlook (Revenue, USD Million, 2015 - 2026)
Human African Trypanosomiasis (Sleeping Sickness)
Product Type Outlook (Revenue, USD Million, 2015 - 2026)
Regional Outlook (Revenue, USD Million, 2015 - 2026)
Middle East & Africa
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Multiple therapeutic regimens are being followed across the globe in attempts to come up with a reliable treatment for Covid-19. One line of treatment includes the use of hydroxychloroquine, while a second treatment line focuses to use antiviral drugs used in the disease management of HIV. Both these approaches have surged demand from advanced antivirals and antimalarial drugs. This impacts the drug manufacturers as an off label indication for these drug classes has to be worked upon. At the moment, the WHO has not prescribed any of these approaches, neither they have commented if one is better than the other. The report will account for Covid19 as a key market contributor.